Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP3 | EGFR | ENSBTAP00000021099 | ENSBTAP00000070620 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Receptor protein-tyrosine kinase. | 0.799 |
| CASP3 | SHH | ENSBTAP00000021099 | ENSBTAP00000034059 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.606 |
| CASP3 | SMO | ENSBTAP00000021099 | ENSBTAP00000017670 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.418 |
| EGFR | CASP3 | ENSBTAP00000070620 | ENSBTAP00000021099 | Receptor protein-tyrosine kinase. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.799 |
| EGFR | GLI2 | ENSBTAP00000070620 | ENSBTAP00000015510 | Receptor protein-tyrosine kinase. | GLI family zinc finger 2. | 0.433 |
| EGFR | PTCH1 | ENSBTAP00000070620 | ENSBTAP00000055675 | Receptor protein-tyrosine kinase. | SSD domain-containing protein. | 0.581 |
| EGFR | SHH | ENSBTAP00000070620 | ENSBTAP00000034059 | Receptor protein-tyrosine kinase. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.656 |
| EGFR | SMO | ENSBTAP00000070620 | ENSBTAP00000017670 | Receptor protein-tyrosine kinase. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.535 |
| GLI2 | EGFR | ENSBTAP00000015510 | ENSBTAP00000070620 | GLI family zinc finger 2. | Receptor protein-tyrosine kinase. | 0.433 |
| GLI2 | PTCH1 | ENSBTAP00000015510 | ENSBTAP00000055675 | GLI family zinc finger 2. | SSD domain-containing protein. | 0.928 |
| GLI2 | PTCH2 | ENSBTAP00000015510 | ENSBTAP00000033224 | GLI family zinc finger 2. | Patched 2. | 0.834 |
| GLI2 | SHH | ENSBTAP00000015510 | ENSBTAP00000034059 | GLI family zinc finger 2. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.905 |
| GLI2 | SMO | ENSBTAP00000015510 | ENSBTAP00000017670 | GLI family zinc finger 2. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.961 |
| GLI2 | SUFU | ENSBTAP00000015510 | ENSBTAP00000069136 | GLI family zinc finger 2. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.998 |
| PTCH1 | EGFR | ENSBTAP00000055675 | ENSBTAP00000070620 | SSD domain-containing protein. | Receptor protein-tyrosine kinase. | 0.581 |
| PTCH1 | GLI2 | ENSBTAP00000055675 | ENSBTAP00000015510 | SSD domain-containing protein. | GLI family zinc finger 2. | 0.928 |
| PTCH1 | SHH | ENSBTAP00000055675 | ENSBTAP00000034059 | SSD domain-containing protein. | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. | 0.999 |
| PTCH1 | SMO | ENSBTAP00000055675 | ENSBTAP00000017670 | SSD domain-containing protein. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.998 |
| PTCH1 | SUFU | ENSBTAP00000055675 | ENSBTAP00000069136 | SSD domain-containing protein. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.930 |
| PTCH2 | GLI2 | ENSBTAP00000033224 | ENSBTAP00000015510 | Patched 2. | GLI family zinc finger 2. | 0.834 |
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