node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HNRNPA1 | HNRNPF | ENSBTAP00000013110 | ENSBTAP00000011658 | Uncharacterized protein. | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | 0.873 |
HNRNPA1 | HNRNPH1 | ENSBTAP00000013110 | ENSBTAP00000074169 | Uncharacterized protein. | Heterogeneous nuclear ribonucleoprotein H1. | 0.891 |
HNRNPA1 | HNRNPL | ENSBTAP00000013110 | ENSBTAP00000031993 | Uncharacterized protein. | Heterogeneous nuclear ribonucleoprotein L. | 0.900 |
HNRNPA1 | HNRNPU | ENSBTAP00000013110 | ENSBTAP00000048368 | Uncharacterized protein. | Heterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). | 0.913 |
HNRNPA1 | PTBP1 | ENSBTAP00000013110 | ENSBTAP00000066720 | Uncharacterized protein. | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). | 0.968 |
HNRNPA1 | RBFOX1 | ENSBTAP00000013110 | ENSBTAP00000069783 | Uncharacterized protein. | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue- specific exons and of differentially spliced exons during erythropoiesis (By similarity). | 0.622 |
HNRNPA1 | SF3A1 | ENSBTAP00000013110 | ENSBTAP00000004398 | Uncharacterized protein. | Splicing factor 3A subunit 1; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes. | 0.443 |
HNRNPA1 | SF3A2 | ENSBTAP00000013110 | ENSBTAP00000062091 | Uncharacterized protein. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.517 |
HNRNPA1 | SRSF1 | ENSBTAP00000013110 | ENSBTAP00000059261 | Uncharacterized protein. | Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] | 0.938 |
HNRNPA1 | SRSF10 | ENSBTAP00000013110 | ENSBTAP00000010616 | Uncharacterized protein. | FUS interacting protein (Serine/arginine-rich) 1. | 0.675 |
HNRNPA1 | SRSF7 | ENSBTAP00000013110 | ENSBTAP00000033048 | Uncharacterized protein. | Serine/arginine-rich splicing factor 7; Required for pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi- sequence specific (By similarity); Belongs to the splicing factor SR family. | 0.885 |
HNRNPA1 | SRSF9 | ENSBTAP00000013110 | ENSBTAP00000016997 | Uncharacterized protein. | Serine and arginine rich splicing factor 9. | 0.824 |
HNRNPA1 | TRA2B | ENSBTAP00000013110 | ENSBTAP00000002225 | Uncharacterized protein. | Transformer-2 protein homolog beta; Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity); Belongs to the splicing factor SR family. | 0.684 |
HNRNPF | HNRNPA1 | ENSBTAP00000011658 | ENSBTAP00000013110 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Uncharacterized protein. | 0.873 |
HNRNPF | HNRNPH1 | ENSBTAP00000011658 | ENSBTAP00000074169 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Heterogeneous nuclear ribonucleoprotein H1. | 0.646 |
HNRNPF | HNRNPL | ENSBTAP00000011658 | ENSBTAP00000031993 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Heterogeneous nuclear ribonucleoprotein L. | 0.847 |
HNRNPF | HNRNPU | ENSBTAP00000011658 | ENSBTAP00000048368 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Heterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). | 0.900 |
HNRNPF | LOC785761 | ENSBTAP00000011658 | ENSBTAP00000062134 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May bind to specific miRNA hairpins. Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1. | 0.808 |
HNRNPF | PTBP1 | ENSBTAP00000011658 | ENSBTAP00000066720 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). | 0.747 |
HNRNPF | RBFOX1 | ENSBTAP00000011658 | ENSBTAP00000069783 | Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity). | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue- specific exons and of differentially spliced exons during erythropoiesis (By similarity). | 0.447 |