node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | GLI2 | ENSBTAP00000036739 | ENSBTAP00000015510 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | GLI family zinc finger 2. | 0.588 |
ACTB | GLI3 | ENSBTAP00000036739 | ENSBTAP00000033519 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | GLI family zinc finger 3. | 0.486 |
ACTB | IFT88 | ENSBTAP00000036739 | ENSBTAP00000073403 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Intraflagellar transport 88. | 0.420 |
ACTB | KRT1 | ENSBTAP00000036739 | ENSBTAP00000055471 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Keratin 1; Belongs to the intermediate filament family. | 0.632 |
ACTB | KRT14 | ENSBTAP00000036739 | ENSBTAP00000036252 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. | 0.544 |
ACTB | LEF1 | ENSBTAP00000036739 | ENSBTAP00000061494 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Lymphoid enhancer binding factor 1. | 0.636 |
ACTB | POLR2A | ENSBTAP00000036739 | ENSBTAP00000065848 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.610 |
ACTB | PTCH1 | ENSBTAP00000036739 | ENSBTAP00000055675 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | SSD domain-containing protein. | 0.571 |
ARL13B | GLI2 | ENSBTAP00000006796 | ENSBTAP00000015510 | ADP ribosylation factor like GTPase 13B. | GLI family zinc finger 2. | 0.716 |
ARL13B | GLI3 | ENSBTAP00000006796 | ENSBTAP00000033519 | ADP ribosylation factor like GTPase 13B. | GLI family zinc finger 3. | 0.814 |
ARL13B | IFT88 | ENSBTAP00000006796 | ENSBTAP00000073403 | ADP ribosylation factor like GTPase 13B. | Intraflagellar transport 88. | 0.951 |
ARL13B | INTU | ENSBTAP00000006796 | ENSBTAP00000017038 | ADP ribosylation factor like GTPase 13B. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.496 |
ARL13B | KIF3A | ENSBTAP00000006796 | ENSBTAP00000035688 | ADP ribosylation factor like GTPase 13B. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.852 |
ARL13B | PTCH1 | ENSBTAP00000006796 | ENSBTAP00000055675 | ADP ribosylation factor like GTPase 13B. | SSD domain-containing protein. | 0.701 |
GLI2 | ACTB | ENSBTAP00000015510 | ENSBTAP00000036739 | GLI family zinc finger 2. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.588 |
GLI2 | ARL13B | ENSBTAP00000015510 | ENSBTAP00000006796 | GLI family zinc finger 2. | ADP ribosylation factor like GTPase 13B. | 0.716 |
GLI2 | GLI3 | ENSBTAP00000015510 | ENSBTAP00000033519 | GLI family zinc finger 2. | GLI family zinc finger 3. | 0.923 |
GLI2 | IFT88 | ENSBTAP00000015510 | ENSBTAP00000073403 | GLI family zinc finger 2. | Intraflagellar transport 88. | 0.819 |
GLI2 | INTU | ENSBTAP00000015510 | ENSBTAP00000017038 | GLI family zinc finger 2. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.504 |
GLI2 | KIF3A | ENSBTAP00000015510 | ENSBTAP00000035688 | GLI family zinc finger 2. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.966 |