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ENO3 ENO3 ENO1 ENO1 IDH2 IDH2 ALDOC ALDOC ENO2 ENO2 MDH2 MDH2 ME1 ME1 PGK1 PGK1 PKLR PKLR ALDOA ALDOA PKM PKM ENO4 ENO4 ACTB ACTB DLD DLD IDH1 IDH1 MDH1 MDH1 ALB ALB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENO3Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. (576 aa)
ENO1Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). (500 aa)
IDH2Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (510 aa)
ENO2ENO2 protein. (434 aa)
MDH2Malate dehydrogenase, mitochondrial. (338 aa)
ME1Malic enzyme. (571 aa)
PGK1Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. (417 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (526 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
ENO4Enolase 4. (613 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
IDH1Isocitrate dehydrogenase [NADP] cytoplasmic; May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. (414 aa)
MDH1Malate dehydrogenase, cytoplasmic. (334 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] (607 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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