node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCB11 | ALB | ENSBTAP00000043977 | ENSBTAP00000022763 | ATP binding cassette subfamily B member 11. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.472 |
ABCB11 | CYP1A1 | ENSBTAP00000043977 | ENSBTAP00000053212 | ATP binding cassette subfamily B member 11. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.444 |
ABCB11 | UGT1A1 | ENSBTAP00000043977 | ENSBTAP00000036928 | ATP binding cassette subfamily B member 11. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.575 |
ALB | ABCB11 | ENSBTAP00000022763 | ENSBTAP00000043977 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | ATP binding cassette subfamily B member 11. | 0.472 |
ALB | CYP1A1 | ENSBTAP00000022763 | ENSBTAP00000053212 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.680 |
ALB | GSTA1 | ENSBTAP00000022763 | ENSBTAP00000068850 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Glutathione S-transferase. | 0.404 |
ALB | HK1 | ENSBTAP00000022763 | ENSBTAP00000063116 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine (By similarity). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor f [...] | 0.667 |
ALB | HK2 | ENSBTAP00000022763 | ENSBTAP00000053231 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Hexokinase 2. | 0.665 |
ALB | HKDC1 | ENSBTAP00000022763 | ENSBTAP00000044680 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Hexokinase domain containing 1. | 0.662 |
ALB | INS | ENSBTAP00000022763 | ENSBTAP00000069398 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.994 |
ALB | UGT1A1 | ENSBTAP00000022763 | ENSBTAP00000036928 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.693 |
CYP1A1 | ABCB11 | ENSBTAP00000053212 | ENSBTAP00000043977 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | ATP binding cassette subfamily B member 11. | 0.444 |
CYP1A1 | ALB | ENSBTAP00000053212 | ENSBTAP00000022763 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.680 |
CYP1A1 | CYP4A11 | ENSBTAP00000053212 | ENSBTAP00000048143 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.952 |
CYP1A1 | GSTA1 | ENSBTAP00000053212 | ENSBTAP00000068850 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase. | 0.965 |
CYP1A1 | GSTA4 | ENSBTAP00000053212 | ENSBTAP00000063570 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase A4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.925 |
CYP1A1 | GSTM1 | ENSBTAP00000053212 | ENSBTAP00000021896 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 1; Belongs to the GST superfamily. | 0.966 |
CYP1A1 | GSTM1-2 | ENSBTAP00000053212 | ENSBTAP00000062183 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.638 |
CYP1A1 | INS | ENSBTAP00000053212 | ENSBTAP00000069398 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.498 |
CYP1A1 | LOC100295687 | ENSBTAP00000053212 | ENSBTAP00000016866 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Protects against the thiol-mediated metal-catalysed oxidative inactivation of enzymes. Belongs to the GST superfamily. Mu family. | 0.667 |