node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | IFT88 | ENSBTAP00000022763 | ENSBTAP00000073403 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Intraflagellar transport 88. | 0.404 |
ALB | LGALS4 | ENSBTAP00000022763 | ENSBTAP00000021701 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Galectin-4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (By similarity). | 0.694 |
ALB | PMEL | ENSBTAP00000022763 | ENSBTAP00000005250 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | Melanocyte protein PMEL; Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures (By similarity). | 0.534 |
CCZ1 | RABGEF1 | ENSBTAP00000004259 | ENSBTAP00000005011 | Vacuolar fusion protein CCZ1 homolog; Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. | Rab5 GDP/GTP exchange factor; Rab effector protein acting as linker between gamma-adaptin and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. | 0.760 |
CCZ1 | YKT6 | ENSBTAP00000004259 | ENSBTAP00000000341 | Vacuolar fusion protein CCZ1 homolog; Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.638 |
CPLANE2 | EVI5 | ENSBTAP00000018903 | ENSBTAP00000040066 | Ciliogenesis and planar polarity effector 2. | Ecotropic viral integration site 5. | 0.413 |
CPLANE2 | EVI5L | ENSBTAP00000018903 | ENSBTAP00000049706 | Ciliogenesis and planar polarity effector 2. | Ecotropic viral integration site 5 like. | 0.586 |
CPLANE2 | IFT88 | ENSBTAP00000018903 | ENSBTAP00000073403 | Ciliogenesis and planar polarity effector 2. | Intraflagellar transport 88. | 0.504 |
CPLANE2 | INTU | ENSBTAP00000018903 | ENSBTAP00000017038 | Ciliogenesis and planar polarity effector 2. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.977 |
CPLANE2 | RAB23 | ENSBTAP00000018903 | ENSBTAP00000007050 | Ciliogenesis and planar polarity effector 2. | RAB23, member RAS oncogene family. | 0.709 |
CPLANE2 | TBC1D30 | ENSBTAP00000018903 | ENSBTAP00000061347 | Ciliogenesis and planar polarity effector 2. | TBC1 domain family member 30. | 0.547 |
EVI5 | CPLANE2 | ENSBTAP00000040066 | ENSBTAP00000018903 | Ecotropic viral integration site 5. | Ciliogenesis and planar polarity effector 2. | 0.413 |
EVI5L | CPLANE2 | ENSBTAP00000049706 | ENSBTAP00000018903 | Ecotropic viral integration site 5 like. | Ciliogenesis and planar polarity effector 2. | 0.586 |
EVI5L | INTU | ENSBTAP00000049706 | ENSBTAP00000017038 | Ecotropic viral integration site 5 like. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.566 |
EVI5L | RAB23 | ENSBTAP00000049706 | ENSBTAP00000007050 | Ecotropic viral integration site 5 like. | RAB23, member RAS oncogene family. | 0.486 |
IFT88 | ALB | ENSBTAP00000073403 | ENSBTAP00000022763 | Intraflagellar transport 88. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] | 0.404 |
IFT88 | CPLANE2 | ENSBTAP00000073403 | ENSBTAP00000018903 | Intraflagellar transport 88. | Ciliogenesis and planar polarity effector 2. | 0.504 |
IFT88 | INTU | ENSBTAP00000073403 | ENSBTAP00000017038 | Intraflagellar transport 88. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.511 |
IFT88 | PMEL | ENSBTAP00000073403 | ENSBTAP00000005250 | Intraflagellar transport 88. | Melanocyte protein PMEL; Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures (By similarity). | 0.752 |
IFT88 | RAB23 | ENSBTAP00000073403 | ENSBTAP00000007050 | Intraflagellar transport 88. | RAB23, member RAS oncogene family. | 0.426 |