Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARSE | STS | ENSBTAP00000047083 | ENSBTAP00000062578 | Arylsulfatase E. | Steroid sulfatase. | 0.418 |
| COMT | CYP1A1 | ENSBTAP00000025997 | ENSBTAP00000053212 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.967 |
| COMT | CYP1A2 | ENSBTAP00000025997 | ENSBTAP00000000094 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.600 |
| COMT | CYP1B1 | ENSBTAP00000025997 | ENSBTAP00000057658 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.972 |
| COMT | SULT1A1 | ENSBTAP00000025997 | ENSBTAP00000011388 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Sulfotransferase 1A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk (By similarity). | 0.685 |
| COMT | SULT1E1 | ENSBTAP00000025997 | ENSBTAP00000015862 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Sulfotransferase 1E1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (By similarity). Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine (By similarity). | 0.427 |
| COMT | UGT1A1 | ENSBTAP00000025997 | ENSBTAP00000036928 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.851 |
| CYP1A1 | COMT | ENSBTAP00000053212 | ENSBTAP00000025997 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.967 |
| CYP1A1 | CYP1A2 | ENSBTAP00000053212 | ENSBTAP00000000094 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.939 |
| CYP1A1 | CYP1B1 | ENSBTAP00000053212 | ENSBTAP00000057658 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.932 |
| CYP1A1 | GSTA2 | ENSBTAP00000053212 | ENSBTAP00000043661 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase A2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.437 |
| CYP1A1 | NQO1 | ENSBTAP00000053212 | ENSBTAP00000071181 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | NAD(P)H quinone dehydrogenase 1. | 0.679 |
| CYP1A1 | STS | ENSBTAP00000053212 | ENSBTAP00000062578 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Steroid sulfatase. | 0.919 |
| CYP1A1 | SULT1A1 | ENSBTAP00000053212 | ENSBTAP00000011388 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Sulfotransferase 1A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk (By similarity). | 0.695 |
| CYP1A1 | SULT1E1 | ENSBTAP00000053212 | ENSBTAP00000015862 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Sulfotransferase 1E1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (By similarity). Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine (By similarity). | 0.933 |
| CYP1A1 | UGT1A1 | ENSBTAP00000053212 | ENSBTAP00000036928 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.986 |
| CYP1A2 | COMT | ENSBTAP00000000094 | ENSBTAP00000025997 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.600 |
| CYP1A2 | CYP1A1 | ENSBTAP00000000094 | ENSBTAP00000053212 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.939 |
| CYP1A2 | CYP1B1 | ENSBTAP00000000094 | ENSBTAP00000057658 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.942 |
| CYP1A2 | GSTA2 | ENSBTAP00000000094 | ENSBTAP00000043661 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Glutathione S-transferase A2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.424 |
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