ATP binding cassette subfamily A member 1.

Uncharacterized protein.

ATP binding cassette subfamily A member 1.

ATP binding cassette subfamily G member 1.

ATP binding cassette subfamily A member 1.

ATP binding cassette subfamily G member 5.

ATP binding cassette subfamily A member 1.

Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.

ATP binding cassette subfamily A member 1.

Cytochrome P450, family 8, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.

ATP binding cassette subfamily A member 1.

Oxysterols receptor LXR-alpha; Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubi [...]

ATP binding cassette subfamily A member 1.

Bile acid receptor; Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA). Plays a essential role in BA homeostasis through the regulation of genes involved in BA synthesis, conjugation and enterohepatic circulation. Also regulates lipid and glucose homeostasis and is involved innate immune response. The FXR-RXR heterodimer binds predominantly to farnesoid X receptor response elements (FXREs) containing two inverted repeats of the consensus sequence 5'-AGGTCA-3' in wh [...]

ATP binding cassette subfamily A member 1.

Nuclear receptor subfamily 1 group I member 2.

ATP binding cassette subfamily A member 1.

Peroxisome proliferative activated receptor, alpha isoform 1.

ATP binding cassette subfamily A member 1.

Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]

Uncharacterized protein.

ATP binding cassette subfamily A member 1.

Uncharacterized protein.

ATP binding cassette subfamily G member 1.

Uncharacterized protein.

Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.

Uncharacterized protein.

Uncharacterized protein; Belongs to the cytochrome P450 family.

Uncharacterized protein.

Nuclear receptor subfamily 1 group I member 2.

Uncharacterized protein.

Nuclear receptor subfamily 1 group I member 3.

ATP binding cassette subfamily B member 11.

ATP binding cassette subfamily G member 5.

ATP binding cassette subfamily B member 11.

Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.

ATP binding cassette subfamily B member 11.

Uncharacterized protein; Belongs to the cytochrome P450 family.

ATP binding cassette subfamily B member 11.

Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.