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AK8 AK8 LOC100125266 LOC100125266 NFS1 NFS1 NTPCR NTPCR LOC528262 LOC528262 LOC516378 LOC516378 AK2 AK2 ALPI ALPI AK4 AK4 AK7 AK7 ACP1-2 ACP1-2 THTPA THTPA LOC101906254 LOC101906254 AK1 AK1 ALPL ALPL AK5 AK5 TPK1 TPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AK8Adenylate kinase 8; Belongs to the adenylate kinase family. (498 aa)
LOC100125266Intestinal-type alkaline phosphatase; Belongs to the alkaline phosphatase family. (533 aa)
NFS1NFS1 protein. (457 aa)
NTPCRCancer-related nucleoside-triphosphatase homolog; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency (By similarity). (190 aa)
LOC528262Uncharacterized protein; Belongs to the alkaline phosphatase family. (529 aa)
LOC516378Uncharacterized protein; Belongs to the alkaline phosphatase family. (531 aa)
AK2Adenylate kinase 2, mitochondrial, N-terminally processed; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (234 aa)
ALPIAlkaline phosphatase. (533 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates (By similarity). Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor (By similarity). Also displays broad nucleoside diphosphate kinase activity (By similarity). Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK (By similarity). Plays a protective role in the cellular r [...] (223 aa)
AK7Adenylate kinase 7. (724 aa)
ACP1-2Low molecular weight phosphotyrosine protein phosphatase; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (194 aa)
THTPAThiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). Belongs to the ThTPase family. (272 aa)
LOC101906254Uncharacterized protein; Belongs to the alkaline phosphatase family. (519 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (230 aa)
ALPLAlkaline phosphatase, tissue-nonspecific isozyme; This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi); Belongs to the alkaline phosphatase family. (524 aa)
AK5Adenylate kinase isoenzyme 5; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity. (562 aa)
TPK1Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate (By similarity). (243 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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