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livF livF lptB lptB AMJ39814.1 AMJ39814.1 livH livH braC braC secA secA spo0A_1 spo0A_1 AMJ40090.1 AMJ40090.1 secY secY kdpE_1 kdpE_1 appA appA luxS_1 luxS_1 agrB_1 agrB_1 AMJ40807.1 AMJ40807.1 AMJ40906.1 AMJ40906.1 AMJ40907.1 AMJ40907.1 czcS czcS saeR saeR AMJ41053.1 AMJ41053.1 AMJ41054.1 AMJ41054.1 yxlF_2 yxlF_2 AMJ41102.1 AMJ41102.1 AMJ41103.1 AMJ41103.1 AMJ41133.1 AMJ41133.1 kdpE_2 kdpE_2 agrB_2 agrB_2 ffh ffh luxS_2 luxS_2 kdpE_3 kdpE_3 ftsY ftsY spo0A_2 spo0A_2 pabA pabA trpE trpE secE secE ribD ribD phoR_6 phoR_6 yidC yidC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
livFHigh-affinity branched-chain amino acid transport ATP-binding protein LivF. (237 aa)
lptBLipopolysaccharide export system ATP-binding protein LptB. (280 aa)
AMJ39814.1Leucine/isoleucine/valine transporter permease subunit; Belongs to the binding-protein-dependent transport system permease family. (362 aa)
livHHigh-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
braCLeucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor. (410 aa)
secAProtein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (857 aa)
spo0A_1Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (263 aa)
AMJ40090.1Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (80 aa)
secYProtein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (421 aa)
kdpE_1KDP operon transcriptional regulatory protein KdpE. (233 aa)
appAOligopeptide-binding protein AppA precursor. (533 aa)
luxS_1S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (154 aa)
agrB_1Accessory protein regulator protein B. (190 aa)
AMJ40807.1Sensory histidine kinase DcuS. (423 aa)
AMJ40906.1Hypothetical protein. (140 aa)
AMJ40907.1Hypothetical protein. (151 aa)
czcSSensor protein CzcS precursor. (454 aa)
saeRResponse regulator SaeR. (219 aa)
AMJ41053.1ABC-2 family transporter protein. (250 aa)
AMJ41054.1ABC-2 family transporter protein. (241 aa)
yxlF_2Putative ABC transporter ATP-binding protein YxlF. (234 aa)
AMJ41102.1Hypothetical protein. (141 aa)
AMJ41103.1Hypothetical protein. (158 aa)
AMJ41133.1Preprotein translocase subunit YajC. (154 aa)
kdpE_2KDP operon transcriptional regulatory protein KdpE. (232 aa)
agrB_2Accessory protein regulator protein B. (188 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (446 aa)
luxS_2S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (161 aa)
kdpE_3KDP operon transcriptional regulatory protein KdpE. (231 aa)
ftsYSignal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (499 aa)
spo0A_2Stage 0 sporulation protein A. (270 aa)
pabAAminodeoxychorismate/anthranilate synthase component 2. (187 aa)
trpEAnthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (487 aa)
secEProtein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. (85 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa)
phoR_6Phosphate regulon sensor protein PhoR. (426 aa)
yidCMembrane protein insertase YidC. (353 aa)
Your Current Organism:
Anaerotignum propionicum
NCBI taxonomy Id: 991789
Other names: A. propionicum DSM 1682, Anaerotignum propionicum DSM 1682, Clostridium propionicum ATCC 25522
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