STRINGSTRING
ADZ68567.1 ADZ68567.1 guaA2 guaA2 apt apt ade ade gpt gpt adk adk ADZ70223.1 ADZ70223.1 ADZ70243.1 ADZ70243.1 cpdA cpdA ADZ70600.1 ADZ70600.1 tatA tatA tatB tatB tatC tatC serS serS surE surE pcm pcm ADZ70626.1 ADZ70626.1 mazG mazG gmk gmk ADZ70851.1 ADZ70851.1 guaA guaA guaB guaB ADZ71520.1 ADZ71520.1 amn amn ADZ71907.1 ADZ71907.1 ADZ72103.1 ADZ72103.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ68567.1Hypoxanthine phosphoribosyltransferase protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (187 aa)
guaA2Class I glutamine amidotransferase domain protein. (251 aa)
aptAdenine phosphoribosyltransferase protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (177 aa)
adeAdenine deaminase 1; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (572 aa)
gptPhosphoribosyl transferase domain, putative; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (169 aa)
adkAdenylate kinase (ATP-AMP transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
ADZ70223.1Ser/Thr protein phosphatase family protein; Belongs to the 5'-nucleotidase family. (670 aa)
ADZ70243.1Adenylate and Guanylate cyclase catalytic domain protein. (413 aa)
cpdASer/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (284 aa)
ADZ70600.1Hypothetical protein. (290 aa)
tatASec-independent protein translocase protein tatA/E-like protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (79 aa)
tatBTwin arginine-targeting protein translocase TatB, putative; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (145 aa)
tatCTwin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (265 aa)
serSSeryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
surE5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa)
pcmL-isoaspartyl protein carboxyl methyltransferase protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (226 aa)
ADZ70626.1M23 peptidase domain protein. (426 aa)
mazGNTP pyrophosphohydrolase protein MazG. (273 aa)
gmkGuanylate kinase (GMP kinase) protein; Essential for recycling GMP and indirectly, cGMP. (230 aa)
ADZ70851.1Hypothetical protein. (285 aa)
guaAGMP synthase-glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. (515 aa)
guaBInosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (502 aa)
ADZ71520.1Probable 5'-nucleotidase (Signal peptide) protein; Belongs to the 5'-nucleotidase family. (537 aa)
amnPurine and other phosphorylase, family 1; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (502 aa)
ADZ71907.1Glutamine amidotransferase class-I. (234 aa)
ADZ72103.1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (331 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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