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ADZ68474.1 ADZ68474.1 dut dut tdk tdk nrdF nrdF nrdE nrdE ADZ69878.1 ADZ69878.1 pyrG pyrG tmk tmk ADZ70793.1 ADZ70793.1 ADZ70795.1 ADZ70795.1 ndk ndk dcd dcd ADZ71811.1 ADZ71811.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ68474.1Conserved hypothetical membrane protein. (172 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa)
tdkPutative thymidine kinase. (200 aa)
nrdFRibonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (325 aa)
nrdERibonucleotide-diphosphate reductase alpha subunit. (145 aa)
ADZ69878.1Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit. (73 aa)
pyrGCTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (231 aa)
ADZ70793.1Ribonucleotide-diphosphate reductase alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1229 aa)
ADZ70795.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, putative; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1004 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
dcd2'-deoxycytidine 5'-triphosphate deaminase superfamily. (369 aa)
ADZ71811.1Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (205 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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