STRINGSTRING
ADZ69260.1 ADZ69260.1 coaA coaA ADZ68458.1 ADZ68458.1 ADZ68471.1 ADZ68471.1 coaE coaE ADZ68510.1 ADZ68510.1 ADZ68594.1 ADZ68594.1 ADZ68650.1 ADZ68650.1 folK folK ADZ68696.1 ADZ68696.1 ADZ68744.1 ADZ68744.1 pdxK pdxK aroK aroK ADZ68822.1 ADZ68822.1 ADZ68846.1 ADZ68846.1 ADZ68848.1 ADZ68848.1 phnN phnN ADZ68889.1 ADZ68889.1 ADZ68908.1 ADZ68908.1 ADZ68971.1 ADZ68971.1 ackA ackA ADZ69177.1 ADZ69177.1 xylB xylB ADZ69190.1 ADZ69190.1 degS degS pyk pyk ADZ69295.1 ADZ69295.1 ADZ69307.1 ADZ69307.1 pgk pgk pal pal ADZ69376.1 ADZ69376.1 ADZ69377.1 ADZ69377.1 ADZ69420.1 ADZ69420.1 ADZ69434.1 ADZ69434.1 ADZ69435.1 ADZ69435.1 glpK glpK ADZ69524.1 ADZ69524.1 ADZ69562.1 ADZ69562.1 prs prs ADZ69631.1 ADZ69631.1 tdk tdk ADZ69671.1 ADZ69671.1 ADZ69797.1 ADZ69797.1 ADZ69812.1 ADZ69812.1 ADZ69828.1 ADZ69828.1 thiM thiM ADZ69907.1 ADZ69907.1 ADZ69927.1 ADZ69927.1 ADZ69939.1 ADZ69939.1 ADZ69980.1 ADZ69980.1 ADZ69987.1 ADZ69987.1 ispE ispE ppdK ppdK ADZ70043.1 ADZ70043.1 ADZ70080.1 ADZ70080.1 nadK nadK adk adk ADZ70236.1 ADZ70236.1 thiL thiL ADZ70362.1 ADZ70362.1 ADZ70455.1 ADZ70455.1 pyrH pyrH ADZ70547.1 ADZ70547.1 tmk tmk ADZ70728.1 ADZ70728.1 ADZ70733.1 ADZ70733.1 ADZ70792.1 ADZ70792.1 ADZ70797.1 ADZ70797.1 ppk ppk ndk ndk gmk gmk ADZ71005.1 ADZ71005.1 ADZ71075.1 ADZ71075.1 ADZ71103.1 ADZ71103.1 cysC cysC ADZ71223.1 ADZ71223.1 ADZ71249.1 ADZ71249.1 ADZ71321.1 ADZ71321.1 ADZ71323.1 ADZ71323.1 ADZ71335.1 ADZ71335.1 ADZ71371.1 ADZ71371.1 ADZ71425.1 ADZ71425.1 coxC coxC ADZ71447.1 ADZ71447.1 ADZ71468.1 ADZ71468.1 ADZ71476.1 ADZ71476.1 ADZ71539.1 ADZ71539.1 ADZ71627.1 ADZ71627.1 ADZ71641.1 ADZ71641.1 ADZ71644.1 ADZ71644.1 ADZ71661.1 ADZ71661.1 ADZ71703.1 ADZ71703.1 thrB thrB ADZ71806.1 ADZ71806.1 ADZ71807.1 ADZ71807.1 lpxK lpxK ADZ71845.1 ADZ71845.1 ADZ71856.1 ADZ71856.1 ribC ribC ADZ71879.1 ADZ71879.1 ADZ71882.1 ADZ71882.1 ADZ71927.1 ADZ71927.1 ADZ71934.1 ADZ71934.1 ADZ71963.1 ADZ71963.1 ADZ72004.1 ADZ72004.1 anmK-2 anmK-2 ADZ72050.1 ADZ72050.1 argB argB tdcD tdcD rbsK rbsK glk glk ADZ72226.1 ADZ72226.1 ADZ72330.1 ADZ72330.1 ADZ72446.1 ADZ72446.1 proB proB cmk cmk ADZ72617.1 ADZ72617.1 ADZ72620.1 ADZ72620.1 ADZ72621.1 ADZ72621.1 ADZ72622.1 ADZ72622.1 ADZ72682.1 ADZ72682.1 ADZ72686.1 ADZ72686.1 ADZ72712.1 ADZ72712.1 ADZ72746.1 ADZ72746.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ69260.1PAS protein. (652 aa)
coaAPantothenate kinase. (321 aa)
ADZ68458.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (438 aa)
ADZ68471.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (773 aa)
coaEdephospho-CoA kinase protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa)
ADZ68510.1Putative phosphotransferase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (261 aa)
ADZ68594.1Putative cAMP-dependent kinase protein. (167 aa)
ADZ68650.1Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S). (671 aa)
folK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. (167 aa)
ADZ68696.1Tetraacyldisaccharide 4'-kinase; Belongs to the UPF0434 family. (63 aa)
ADZ68744.1DNA primase (bacterial type). (345 aa)
pdxKPyridoxine kinase protein; Belongs to the pyridoxine kinase family. (295 aa)
aroKShikimate kinase, 3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (209 aa)
ADZ68822.1Polyphosphate kinase 2 superfamily. (302 aa)
ADZ68846.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (1140 aa)
ADZ68848.1Putative aliphatic amidase expression-regulating protein. (432 aa)
phnNPhosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (197 aa)
ADZ68889.1Sugar kinase, ribokinase family. (306 aa)
ADZ68908.1Aspartokinase; Belongs to the aspartokinase family. (416 aa)
ADZ68971.1Two-component system sensor protein. (458 aa)
ackAAcetate kinase protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (392 aa)
ADZ69177.1Xyl repressor. (421 aa)
xylBPutative xylulose kinase protein. (481 aa)
ADZ69190.1Probable two-component sensor histidine kinase protein. (601 aa)
degSSignal transduction histidine kinase. (476 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
ADZ69295.1Putative hydroxypyruvate reductase; Putative glycerate kinase. (431 aa)
ADZ69307.1Abc1 protein. (459 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
palOmp16 protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (161 aa)
ADZ69376.1Hypothetical protein. (214 aa)
ADZ69377.1CheA-like signal transduction histidine kinase. (918 aa)
ADZ69420.1Phosphoribulokinase 1. (290 aa)
ADZ69434.1Histidine kinase, putative. (751 aa)
ADZ69435.1Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine. (525 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa)
ADZ69524.1Ribose-phosphate pyrophosphokinase family protein. (323 aa)
ADZ69562.1Type III effector Hrp-dependent outer proteins (Hop). (424 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
ADZ69631.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (464 aa)
tdkPutative thymidine kinase. (200 aa)
ADZ69671.1Phosphotransferase enzyme family, putative. (304 aa)
ADZ69797.1Hypothetical protein. (202 aa)
ADZ69812.1Putative membrane-associated protein; Putative diguanylate cyclase (GGDEF)/phosphodiesterase (EAL), with PAS sensor, signal transduction histidine kinase and methyl-accepting chemotaxis domains; putative membrane-associated protein. (980 aa)
ADZ69828.1Putative Kinase inhibitor YbhB. (148 aa)
thiMHydroxyethylthiazole kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (252 aa)
ADZ69907.1Bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase). (270 aa)
ADZ69927.1Hpt domain protein. (123 aa)
ADZ69939.1Polyphosphate kinase 2 family. (376 aa)
ADZ69980.1Sensor kinase. (849 aa)
ADZ69987.1Kinase, pfkB family. (306 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (311 aa)
ppdKPyruvate phosphate dikinase (Pyruvate, orthophosphate dikinase); Belongs to the PEP-utilizing enzyme family. (887 aa)
ADZ70043.1Cyclic diguanylate phosphodiesterase domain protein. (753 aa)
ADZ70080.1Hpt domain protein. (178 aa)
nadKProbable NAD(+) kinase protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (260 aa)
adkAdenylate kinase (ATP-AMP transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
ADZ70236.1Hypothetical protein. (133 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (332 aa)
ADZ70362.1Probable succinoglycan transport protein. (736 aa)
ADZ70455.1Cobinamide kinase / cobinamide phosphate guanyltransferase superfamily; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (185 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
ADZ70547.1Hypothetical protein. (625 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (231 aa)
ADZ70728.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (723 aa)
ADZ70733.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (379 aa)
ADZ70792.1Response regulator receiver domain protein. (252 aa)
ADZ70797.1Fructokinase PfkB; Belongs to the carbohydrate kinase PfkB family. (298 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (743 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
gmkGuanylate kinase (GMP kinase) protein; Essential for recycling GMP and indirectly, cGMP. (230 aa)
ADZ71005.1Periplasmic sensor signal transduction histidine kinase. (457 aa)
ADZ71075.1Putative kinase/transcriptional regulator, actin-like ATPase domain (NagC/XylR (ROK) familiy). (298 aa)
ADZ71103.1Putative transcriptional regulator protein. (152 aa)
cysCBifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (650 aa)
ADZ71223.1CHASE2 domain family. (912 aa)
ADZ71249.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (517 aa)
ADZ71321.1Multi-sensor signal transduction histidine kinase. (787 aa)
ADZ71323.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (484 aa)
ADZ71335.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (459 aa)
ADZ71371.1Sensor histidine kinase with a PAS domain. (588 aa)
ADZ71425.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (469 aa)
coxCCarbon monoxide dehydrogenase operon C protein. (430 aa)
ADZ71447.1Exopolysaccharide transport protein family. (766 aa)
ADZ71468.1Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein. (650 aa)
ADZ71476.1Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S). (750 aa)
ADZ71539.1Aminoglycoside phosphotransferase. (328 aa)
ADZ71627.1Response regulator receiver domain protein (CheY-like). (177 aa)
ADZ71641.1Multi-sensor signal transduction histidine kinase. (385 aa)
ADZ71644.1Sensor histidine kinase, putative proline sensor PrlS. (1174 aa)
ADZ71661.1Sel1 repeat family. (1345 aa)
ADZ71703.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (481 aa)
thrBHomoserine kinase type II; Belongs to the pseudomonas-type ThrB family. (321 aa)
ADZ71806.1Putative Diacylglycerol kinase catalytic domain protein. (315 aa)
ADZ71807.1Diguanylate cyclase/phosphodiesterase with PAS/PAC-like protein. (979 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
ADZ71845.1Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor. (1091 aa)
ADZ71856.1Ammonium transporter, putative. (1049 aa)
ribCRiboflavin kinase/FMN adenylyltransferase protein; Belongs to the ribF family. (333 aa)
ADZ71879.1SlyX superfamily. (70 aa)
ADZ71882.1Cyclic nucleotide-binding:Bacterial regulatory protein, Crp. (229 aa)
ADZ71927.1Aminoglycoside phosphotransferase. (529 aa)
ADZ71934.1PAS domain protein. (1231 aa)
ADZ71963.1Branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein. (397 aa)
ADZ72004.1Cyclic diguanylate phosphodiesterase domain protein. (683 aa)
anmK-2Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (358 aa)
ADZ72050.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (496 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
tdcDPropionate kinase/acetate kinase C, anaerobic; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (301 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (348 aa)
ADZ72226.1Putative ABC transporter substrate-binding protein. (408 aa)
ADZ72330.1Exopolysaccharide polymerization/transport protein. (673 aa)
ADZ72446.1Periplasmic sensor signal transduction histidine kinase. (452 aa)
proBGlutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa)
cmkCytidylate kinase (Cytidine monophosphate kinase) protein. (208 aa)
ADZ72617.1Alkaline phosphatase synthesis sensor protein phor. (807 aa)
ADZ72620.1Phosphotransferase system, mannose/fructose-specific component IIA. (150 aa)
ADZ72621.1Serine kinase of the HPr protein, regulates carbohydrat e metabolism. (155 aa)
ADZ72622.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (607 aa)
ADZ72682.1Polyphosphate kinase 2 family. (489 aa)
ADZ72686.1Hypothetical protein. (319 aa)
ADZ72712.1Ribokinase:Carbohydrate kinase, PfkB. (333 aa)
ADZ72746.1Probable ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (526 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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