STRINGSTRING
ADZ69445.1 ADZ69445.1 ADZ68493.1 ADZ68493.1 ADZ68505.1 ADZ68505.1 aroE-2 aroE-2 ADZ68557.1 ADZ68557.1 leuB leuB gpsA gpsA ADZ68969.1 ADZ68969.1 ADZ68975.1 ADZ68975.1 ADZ68978.1 ADZ68978.1 ADZ69189.1 ADZ69189.1 ADZ69211.1 ADZ69211.1 ADZ69295.1 ADZ69295.1 ADZ69361.1 ADZ69361.1 ADZ69442.1 ADZ69442.1 betA betA mdh mdh ADZ72156.1 ADZ72156.1 ADZ72344.1 ADZ72344.1 ADZ71082.1 ADZ71082.1 ADZ71039.1 ADZ71039.1 ADZ70976.1 ADZ70976.1 ADZ70877.1 ADZ70877.1 guaB guaB pdxA pdxA ADZ70696.1 ADZ70696.1 ADZ70656.1 ADZ70656.1 ADZ70653.1 ADZ70653.1 dxr dxr ribD ribD ADZ70338.1 ADZ70338.1 ADZ69994.1 ADZ69994.1 ADZ69991.1 ADZ69991.1 ADZ69894.1 ADZ69894.1 zwf zwf ADZ69831.1 ADZ69831.1 ilvC ilvC murB murB ADZ69561.1 ADZ69561.1 glpD glpD ADZ69474.1 ADZ69474.1 ADZ71773.1 ADZ71773.1 mvaA mvaA fadB fadB aroE aroE ADZ71597.1 ADZ71597.1 ADZ71590.1 ADZ71590.1 ADZ71584.1 ADZ71584.1 ADZ71583.1 ADZ71583.1 hisD hisD ADZ71396.1 ADZ71396.1 ADZ71244.1 ADZ71244.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ69445.1Methanol dehydrogenase large subunit-like protein. (600 aa)
ADZ68493.1Phosphate acetyl/butyryl transferase subfamily, putative. (760 aa)
ADZ68505.1D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative. (328 aa)
aroE-2Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (281 aa)
ADZ68557.13-hydroxyacyl-CoA dehydrogenase, C-terminal domain family. (293 aa)
leuB3-isopropylmalate dehydrogenase 2; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (335 aa)
ADZ68969.13-hydroxyacyl-CoA dehydrogenase (Hdb-1). (308 aa)
ADZ68975.1Probable 3-isopropylmalate dehydrogenase oxidoreductase protein. (351 aa)
ADZ68978.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (325 aa)
ADZ69189.1FAD dependent oxidoreductase, putative. (542 aa)
ADZ69211.1Putative glycerate dehydrogenase (GyaR-like); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
ADZ69295.1Putative hydroxypyruvate reductase; Putative glycerate kinase. (431 aa)
ADZ69361.1Aspartyl/glutamyl tRNA amidotransferase subunit C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
ADZ69442.1Alcohol dehydrogenase GroES-like protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (552 aa)
mdhMalate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
ADZ72156.1Probable 6-phosphogluconate dehydrogenase protein. (288 aa)
ADZ72344.1Bifunctional deaminase-reductase domain protein. (262 aa)
ADZ71082.1Homoserine dehydrogenase. (433 aa)
ADZ71039.1FAD dependent oxidoreductase, putative. (366 aa)
ADZ70976.1dTDP 4-dehydrorhamnose reductase (DTDP-L-rhamnose synthetase); Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (290 aa)
ADZ70877.16-phosphogluconate dehydrogenase, NAD-binding protein. (298 aa)
guaBInosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (502 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase protein; Belongs to the PdxA family. (315 aa)
ADZ70696.1Putative soluble aldose sugar dehydrogenase Asd-like protein. (379 aa)
ADZ70656.1UDP-glucose 6-dehydrogenase protein. (439 aa)
ADZ70653.1UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)
ribDBifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (388 aa)
ADZ70338.13-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase; Belongs to the HIBADH-related family. (296 aa)
ADZ69994.1Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (762 aa)
ADZ69991.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
ADZ69894.1Oxidoreductase, putative. (523 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
ADZ69831.1D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative. (414 aa)
ilvCAcetohydroxy acid isomeroreductase-like protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (317 aa)
ADZ69561.1Predicted dehydrogenase, with NAD(P)-binding Rossmann-fold domain. (314 aa)
glpDFAD dependent oxidoreductase, putative; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (538 aa)
ADZ69474.1Putative 3-hydroxyisobutyrate dehydrogenase. (322 aa)
ADZ71773.1Phosphate acetyl/butyryl transferase subfamily, putative. (765 aa)
mvaA3-hydroxy-3-methylglutaryl-coenzyme A reductase (MvaA); Belongs to the HMG-CoA reductase family. (425 aa)
fadB3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; Belongs to the enoyl-CoA hydratase/isomerase family. (738 aa)
aroEShikimate 5-dehydrogenase/quinate 5-dehydrogenase family protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa)
ADZ71597.1Probable 6-phosphogluconate dehydrogenase protein. (296 aa)
ADZ71590.1L-lactate dehydrogenase (Cytochrome). (384 aa)
ADZ71584.1Oxidoreductase, GMC family. (59 aa)
ADZ71583.1Putative trifunctional protein; Belongs to the enoyl-CoA hydratase/isomerase family. (691 aa)
hisDHistidinol dehydrogenase 1; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa)
ADZ71396.1Gluconate 2-dehydrogenase (Acceptor). (304 aa)
ADZ71244.1Probable 3-hydroxyisobutyrate dehydrogenase protein. (293 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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