STRINGSTRING
ADZ70469.1 ADZ70469.1 ADZ68970.1 ADZ68970.1 ADZ68976.1 ADZ68976.1 ADZ69152.1 ADZ69152.1 ADZ69219.1 ADZ69219.1 fadD3 fadD3 accD accD fabA fabA fabB fabB ADZ68503.1 ADZ68503.1 ADZ68557.1 ADZ68557.1 ADZ68572.1 ADZ68572.1 ADZ68607.1 ADZ68607.1 ADZ68649.1 ADZ68649.1 tspO tspO ADZ68744.1 ADZ68744.1 ispG ispG accA accA gpsA gpsA mccA mccA ADZ68969.1 ADZ68969.1 ADZ69316.1 ADZ69316.1 ADZ69323.1 ADZ69323.1 ADZ69499.1 ADZ69499.1 ADZ69507.1 ADZ69507.1 ADZ69523.1 ADZ69523.1 ADZ69587.1 ADZ69587.1 ADZ69609.1 ADZ69609.1 ADZ69608.1 ADZ69608.1 ADZ69638.1 ADZ69638.1 ADZ69753.1 ADZ69753.1 murG murG lpxC lpxC lcfA lcfA ADZ69913.1 ADZ69913.1 ADZ70037.1 ADZ70037.1 ispE ispE ADZ70209.1 ADZ70209.1 plsY plsY ADZ70284.1 ADZ70284.1 ADZ70316.1 ADZ70316.1 acpS acpS plsX plsX fabH fabH ADZ70363.1 ADZ70363.1 htrB htrB ADZ70428.1 ADZ70428.1 cls cls idi idi ADZ70453.1 ADZ70453.1 ADZ70471.1 ADZ70471.1 uppS uppS ADZ70523.1 ADZ70523.1 dxr dxr lpxD lpxD fabZ fabZ lpxA lpxA ADZ70530.1 ADZ70530.1 lpxB lpxB ADZ70580.1 ADZ70580.1 kdsA kdsA ADZ70660.1 ADZ70660.1 ADZ70665.1 ADZ70665.1 ADZ70669.1 ADZ70669.1 ispDF ispDF lipA lipA ADZ70741.1 ADZ70741.1 glmU glmU ADZ70827.1 ADZ70827.1 acpP acpP ADZ70830.1 ADZ70830.1 ADZ70844.1 ADZ70844.1 ADZ70938.1 ADZ70938.1 ADZ70941.1 ADZ70941.1 ADZ71026.1 ADZ71026.1 ADZ71152.1 ADZ71152.1 psd psd ADZ71278.1 ADZ71278.1 ADZ71292.1 ADZ71292.1 ADZ71441.1 ADZ71441.1 ADZ71447.1 ADZ71447.1 cysQ cysQ ADZ71497.1 ADZ71497.1 ADZ71498.1 ADZ71498.1 ADZ71583.1 ADZ71583.1 fadB fadB ADZ71678.1 ADZ71678.1 ADZ71707.1 ADZ71707.1 dxs dxs fabI fabI ispH ispH ADZ71806.1 ADZ71806.1 lpxK lpxK ADZ71831.1 ADZ71831.1 ADZ71862.1 ADZ71862.1 ADZ71866.1 ADZ71866.1 yciA yciA ADZ71883.1 ADZ71883.1 ADZ71970.1 ADZ71970.1 ADZ71971.1 ADZ71971.1 ADZ71972.1 ADZ71972.1 ADZ71973.1 ADZ71973.1 ADZ72232.1 ADZ72232.1 ADZ72241.1 ADZ72241.1 ADZ72242.1 ADZ72242.1 ADZ72342.1 ADZ72342.1 ADZ72609.1 ADZ72609.1 ADZ72686.1 ADZ72686.1 ADZ72696.1 ADZ72696.1 kdsB kdsB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ADZ70469.1Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
ADZ68970.1AMP-dependent synthetase and ligase. (549 aa)
ADZ68976.1Methylitaconate delta2-delta3-isomerase. (370 aa)
ADZ69152.1Acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (77 aa)
ADZ69219.1Putative 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family. (484 aa)
fadD3AMP-dependent synthetase and ligase. (661 aa)
accDAcetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (299 aa)
fabABeta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (168 aa)
fabB3-oxoacyl-(Acyl-carrier-protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa)
ADZ68503.1Oxidoreductase, short chain dehydrogenase/reductase family. (270 aa)
ADZ68557.13-hydroxyacyl-CoA dehydrogenase, C-terminal domain family. (293 aa)
ADZ68572.11-acyl-sn-glycerol-3-phosphate acyltransferase protein. (269 aa)
ADZ68607.1Hypothetical protein. (371 aa)
ADZ68649.1Geranyltranstransferase protein; Belongs to the FPP/GGPP synthase family. (303 aa)
tspOTSPO-like protein. (148 aa)
ADZ68744.1DNA primase (bacterial type). (345 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (425 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (335 aa)
mccACarboxyl transferase domain, putative. (535 aa)
ADZ68969.13-hydroxyacyl-CoA dehydrogenase (Hdb-1). (308 aa)
ADZ69316.1AMP-dependent synthetase and ligase. (544 aa)
ADZ69323.1Putative NAD(P)H quinone oxidoreductase, PIG3 family. (333 aa)
ADZ69499.1Carboxyl transferase domain protein. (533 aa)
ADZ69507.1Acyl-CoA synthetase (AMP-forming) / AMP-acid ligase. (650 aa)
ADZ69523.1Protein containing GCN5-related N-acetyltransferase domain. (81 aa)
ADZ69587.1N-terminal double-transmembrane domain protein. (937 aa)
ADZ69609.1MaoC-like dehydratase. (162 aa)
ADZ69608.1MaoC-like dehydratase, putative. (152 aa)
ADZ69638.1CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (190 aa)
ADZ69753.1Hypothetical protein. (497 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (372 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (318 aa)
lcfAAMP-dependent synthetase and ligase. (557 aa)
ADZ69913.1UDP-2,3-diacylglucosamine hydrolase protein. (268 aa)
ADZ70037.1Farnesyl pyrophosphate synthetase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (336 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (311 aa)
ADZ70209.1Carboxyl transferase domain, putative. (510 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (216 aa)
ADZ70284.1Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
ADZ70316.1Thioesterase family protein. (149 aa)
acpS4''''-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (149 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (354 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
ADZ70363.1Hypothetical protein. (424 aa)
htrBLipid A biosynthesis lauroyl acyltransferase. (359 aa)
ADZ70428.1Lipid A biosynthesis-like protein. (104 aa)
clsPhospholipase D active site motif domain protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (499 aa)
idiIsopentenyl-diphosphate delta-isomerase, type 1. (175 aa)
ADZ70453.1Tiorf33 protein. (390 aa)
ADZ70471.1Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
uppSIsoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (231 aa)
ADZ70523.1Phosphatidate cytidylyltransferase; Belongs to the CDS family. (284 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (350 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (267 aa)
ADZ70530.1Phosphatidate cytidyltransferase. (282 aa)
lpxBGlycosyl transferase, family 19; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (398 aa)
ADZ70580.1Enoyl-CoA hydratase / short chain enoyl-CoA hydratase. (266 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (347 aa)
ADZ70660.1Possible acid-CoA ligase. (543 aa)
ADZ70665.1Bacterial lipid A biosynthesis acyltransferase superfamily. (295 aa)
ADZ70669.1CDP-alcohol phosphatidyltransferase family; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (238 aa)
ispDF2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (410 aa)
lipALipoyl synthase 1; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (324 aa)
ADZ70741.1Thioesterase superfamily protein. (142 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (451 aa)
ADZ70827.13-oxoacyl-(Acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (422 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
ADZ70830.1Malonyl CoA-acyl carrier protein transacylase (MCT). (337 aa)
ADZ70844.1Putative transmembrane protein. (190 aa)
ADZ70938.1Putative bifunctional anaerobic fatty acid oxidation complex protein (FadJ/fadB-like): enoyl-CoA hydratase/epimerase/isomerase (N-terminal); 3-hydroxyacyl-CoA dehydrogenase (C-terminal). (460 aa)
ADZ70941.1AMP-dependent synthetase and ligase. (604 aa)
ADZ71026.1Hypothetical conserved membrane protein. (524 aa)
ADZ71152.1CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (295 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (234 aa)
ADZ71278.1FldA-like protein. (344 aa)
ADZ71292.1AMP-dependent synthetase and ligase. (612 aa)
ADZ71441.1Oxidoreductase, short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
ADZ71447.1Exopolysaccharide transport protein family. (766 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (284 aa)
ADZ71497.1Malonyl-CoA decarboxylase protein. (456 aa)
ADZ71498.1AMP-dependent synthetase and ligase. (504 aa)
ADZ71583.1Putative trifunctional protein; Belongs to the enoyl-CoA hydratase/isomerase family. (691 aa)
fadB3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; Belongs to the enoyl-CoA hydratase/isomerase family. (738 aa)
ADZ71678.1CDP-alcohol phosphatidyltransferase superfamily; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (202 aa)
ADZ71707.1Putative ACYL-COA synthetase ligase protein; alkK-like protein. (543 aa)
dxs1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
fabIOxidoreductase, short chain dehydrogenase/reductase family. (278 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (341 aa)
ADZ71806.1Putative Diacylglycerol kinase catalytic domain protein. (315 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (343 aa)
ADZ71831.1RNA polymerase sigma factor; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (431 aa)
ADZ71862.1Probable maoC-like dehydratase. (133 aa)
ADZ71866.1Dehydrogenase with MaoC-like domain. (150 aa)
yciAThioesterase family protein. (138 aa)
ADZ71883.1Glycosyl transferase, family 39. (506 aa)
ADZ71970.1MaoC-like dehydratase, putative. (124 aa)
ADZ71971.1Chain A, (R)-Hydratase; Similar to A. caviae protein; involved in Pha Biosynthesis. (131 aa)
ADZ71972.1O-succinylbenzoic acid-CoA ligase, putative. (514 aa)
ADZ71973.1Enoyl-CoA hydratase/isomerase family protein. (257 aa)
ADZ72232.1AMP-dependent synthetase and ligase. (547 aa)
ADZ72241.1Hypothetical protein. (459 aa)
ADZ72242.1Hypothetical protein. (108 aa)
ADZ72342.1Acyl carrier protein. (83 aa)
ADZ72609.1Hypothetical protein. (115 aa)
ADZ72686.1Hypothetical protein. (319 aa)
ADZ72696.1Putative acetyltransferase protein. (163 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (278 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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