STRINGSTRING
ADZ70506.1 ADZ70506.1 ADZ70505.1 ADZ70505.1 nuoK nuoK nuoI1 nuoI1 nuoH1 nuoH1 ADZ70499.1 ADZ70499.1 cydA cydA nuoE nuoE ADZ70385.1 ADZ70385.1 ADZ71226.1 ADZ71226.1 ADZ69991.1 ADZ69991.1 ADZ68625.1 ADZ68625.1 ADZ69710.1 ADZ69710.1 fdxH fdxH ADZ69698.1 ADZ69698.1 ADZ69602.1 ADZ69602.1 fumC fumC norE norE norB norB ADZ68692.1 ADZ68692.1 ADZ68626.1 ADZ68626.1 sdhB sdhB sdhA sdhA ADZ70062.1 ADZ70062.1 ADZ69994.1 ADZ69994.1 mdh mdh sucC sucC sucD sucD sucA sucA ADZ72605.1 ADZ72605.1 ADZ72343.1 ADZ72343.1 ADZ71904.1 ADZ71904.1 ADZ71896.1 ADZ71896.1 coxA coxA ADZ71816.1 ADZ71816.1 ADZ71771.1 ADZ71771.1 ADZ71749.1 ADZ71749.1 ADZ71729.1 ADZ71729.1 ADZ71634.1 ADZ71634.1 ccoP ccoP ADZ71451.1 ADZ71451.1 glcB glcB ADZ71381.1 ADZ71381.1 ADZ71002.1 ADZ71002.1 cydB cydB ADZ71208.1 ADZ71208.1 ubiE ubiE ADZ70895.1 ADZ70895.1 ADZ70810.1 ADZ70810.1 ADZ70739.1 ADZ70739.1 ADZ70600.1 ADZ70600.1 fdsA fdsA gltA gltA nuoN nuoN
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ70506.1Proton-translocating NADH-quinone oxidoreductase, chain M subfamily. (506 aa)
ADZ70505.1Proton-translocating NADH-quinone oxidoreductase, chain L subfamily. (662 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
nuoI1NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (162 aa)
nuoH1NADH dehydrogenase superfamily; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (349 aa)
ADZ70499.1NADH-quinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (687 aa)
cydAPutative transmembrane cytochrome D ubiquinol oxidase subunit I. (516 aa)
nuoENADH-quinone oxidoreductase, E subunit subfamily, putative. (378 aa)
ADZ70385.1Hypothetical protein. (120 aa)
ADZ71226.1Cytochrome B561. (193 aa)
ADZ69991.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
ADZ68625.1Succinate dehydrogenase, hydrophobic membrane anchor protein, putative. (127 aa)
ADZ69710.1Formate dehydrogenase, gamma subunit. (222 aa)
fdxHFormate dehydrogenase, beta subunit. (302 aa)
ADZ69698.1Cytochrome B561. (166 aa)
ADZ69602.1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (422 aa)
fumCPutative Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
norENorE protein involved in nitric oxide reduction (Cytochrome c oxidase subunit III-like protein). (184 aa)
norBNitric oxide reductase, large subunit. (456 aa)
ADZ68692.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
ADZ68626.1Succinate dehydrogenase, cytochrome b556 subunit. (132 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (608 aa)
ADZ70062.1Hypothetical protein. (204 aa)
ADZ69994.1Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (762 aa)
mdhMalate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
sucCSuccinate--CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (302 aa)
sucAOxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (995 aa)
ADZ72605.1Conserved hypothetical signal peptide protein. (126 aa)
ADZ72343.1Cytochrome B561. (176 aa)
ADZ71904.1Cysteine-rich domain of 2-hydroxy-acid oxidase GlcF-like protein. (258 aa)
ADZ71896.1Glycolate oxidase iron-sulfur subunit. (449 aa)
coxAPutative cytochrome C oxidase polypeptide I transmembrane protein; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (531 aa)
ADZ71816.1Putative cytochrome c oxidase subunit iii transmembrane protein. (290 aa)
ADZ71771.1Electrotransfer ubiquinone oxidoreductase protein; Accepts electrons from ETF and reduces ubiquinone. (557 aa)
ADZ71749.1Methyltransferase type 11. (224 aa)
ADZ71729.1Methyltransferase domain family. (364 aa)
ADZ71634.1Cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (551 aa)
ccoPCytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (292 aa)
ADZ71451.1Putative transglutaminase-like cysteine peptidase protein. (198 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (720 aa)
ADZ71381.1NADH-Ubiquinone/plastoquinone (Complex I), domain protein. (508 aa)
ADZ71002.1Putative cytochrome b. (220 aa)
cydBPutative transmembrane cytochrome bd-II oxidase subunit II. (402 aa)
ADZ71208.1Trimethylamine methyltransferase subfamily; Belongs to the trimethylamine methyltransferase family. (513 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (306 aa)
ADZ70895.1Citrate synthase. (265 aa)
ADZ70810.1Molybdopterin oxidoreductase domain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (720 aa)
ADZ70739.1Cyclase/dehydrase superfamily. (157 aa)
ADZ70600.1Hypothetical protein. (290 aa)
fdsAFormate dehydrogenase, alpha subunit protein. (959 aa)
gltACitrate synthase, chromosomal; Belongs to the citrate synthase family. (430 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (480 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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