STRINGSTRING
acsA acsA ADZ68608.1 ADZ68608.1 acs acs ADZ68888.1 ADZ68888.1 pyk pyk ADZ69333.1 ADZ69333.1 pgk pgk ADZ69337.1 ADZ69337.1 ADZ69418.1 ADZ69418.1 fbp fbp ADZ69442.1 ADZ69442.1 pdhA pdhA ADZ69512.1 ADZ69512.1 ADZ69513.1 ADZ69513.1 ADZ69520.1 ADZ69520.1 ADZ69522.1 ADZ69522.1 pgi pgi ppdK ppdK tpiA tpiA eno eno ADZ70743.1 ADZ70743.1 pdhB pdhB ADZ70745.1 ADZ70745.1 pdhA-3 pdhA-3 glpX glpX ADZ71567.1 ADZ71567.1 ADZ71949.1 ADZ71949.1 ADZ72096.1 ADZ72096.1 ADZ72097.1 ADZ72097.1 glk glk ADZ72506.1 ADZ72506.1 pckA pckA ADZ72646.1 ADZ72646.1 gpmA gpmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
acsAAcetate-CoA ligase, AMP-dependent; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
ADZ68608.1Putative acetyl-coenzyme A synthetase (AcsA-like). (546 aa)
acsAMP-dependent synthetase and ligase. (545 aa)
ADZ68888.1Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system, putative. (262 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
ADZ69333.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (376 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
ADZ69337.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
ADZ69418.1Fructose-bisphosphate aldolase 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
fbpFructose-1,6-bisphosphatase I. (354 aa)
ADZ69442.1Alcohol dehydrogenase GroES-like protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
pdhAPyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (366 aa)
ADZ69512.1Pyruvate dehydrogenase (Acetyl-transferring) E1 component, beta subunit. (326 aa)
ADZ69513.1Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes. (365 aa)
ADZ69520.1AMP-dependent synthetase and ligase. (593 aa)
ADZ69522.1Probable pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase. (411 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (541 aa)
ppdKPyruvate phosphate dikinase (Pyruvate, orthophosphate dikinase); Belongs to the PEP-utilizing enzyme family. (887 aa)
tpiATriosephosphate isomerase 1; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa)
ADZ70743.1Dihydrolipoyl dehydrogenase. (480 aa)
pdhBDihydrolipoamide acetyltransferase protein. (308 aa)
ADZ70745.1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (458 aa)
pdhA-3Pyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (350 aa)
glpXFructose 1,6-bisphosphatase II. (331 aa)
ADZ71567.1Acetyl-CoA synthetase (Acetate-CoA ligase). (519 aa)
ADZ71949.1Aldehyde dehydrogenase 2B4; Belongs to the aldehyde dehydrogenase family. (491 aa)
ADZ72096.1Aldose 1-epimerase subfamily; Converts alpha-aldose to the beta-anomer. (336 aa)
ADZ72097.1Phosphoglucomutase/phosphomannomutase, C-terminal domain family. (499 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (348 aa)
ADZ72506.1Pyruvate dehydrogenase (Acetyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (784 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa)
ADZ72646.1Dihydrolipoamide dehydrogenase protein. (467 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (206 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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