STRINGSTRING
gshB gshB cysK1 cysK1 metX metX asd asd ADZ68908.1 ADZ68908.1 ADZ68978.1 ADZ68978.1 ADZ69075.1 ADZ69075.1 ADZ69132.1 ADZ69132.1 ADZ69360.1 ADZ69360.1 ADZ69361.1 ADZ69361.1 ADZ69427.1 ADZ69427.1 mtnA mtnA mtnP mtnP ilvE-2 ilvE-2 aatA aatA speE speE speH speH ADZ69735.1 ADZ69735.1 ADZ69831.1 ADZ69831.1 cysE cysE ADZ72758.1 ADZ72758.1 ADZ70367.1 ADZ70367.1 metC metC ADZ70436.1 ADZ70436.1 ADZ70440.1 ADZ70440.1 ADZ70562.1 ADZ70562.1 ADZ70881.1 ADZ70881.1 ADZ70892.1 ADZ70892.1 ADZ71019.1 ADZ71019.1 ADZ71082.1 ADZ71082.1 ilvE ilvE ADZ71200.1 ADZ71200.1 ADZ71221.1 ADZ71221.1 ADZ71247.1 ADZ71247.1 ADZ71401.1 ADZ71401.1 metZ metZ ADZ71912.1 ADZ71912.1 ADZ72008.1 ADZ72008.1 ADZ72539.1 ADZ72539.1 ADZ72604.1 ADZ72604.1 ahcY ahcY mdh mdh metK metK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
gshBGlutathione synthetase protein; Belongs to the prokaryotic GSH synthase family. (314 aa)
cysK1Cysteine synthase A. (320 aa)
metXHomoserine O-acetyltransferase (Homoserine O-trans-acetylase) (Homoserine transacetylase) (HTA); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (407 aa)
asdAspartate-B-semialdehyde dehydrogenase protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
ADZ68908.1Aspartokinase; Belongs to the aspartokinase family. (416 aa)
ADZ68978.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (325 aa)
ADZ69075.1Conjugation factor synthetase; TraI. (203 aa)
ADZ69132.1Conjugation factor synthetase; TraI. (187 aa)
ADZ69360.1Phosphoserine aminotransferase protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (390 aa)
ADZ69361.1Aspartyl/glutamyl tRNA amidotransferase subunit C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
ADZ69427.1S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT). (384 aa)
mtnA5-methylthioribose-1-phosphate isomerase (MTNA); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (367 aa)
mtnPPutative 5'-methylthioadenosine phosphorylase (MtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (287 aa)
ilvE-2Putative branched-chain amino acid transferase (IlvE-like); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (299 aa)
aatAAminotransferase, classes I and II superfamily. (399 aa)
speESpermidine synthase 1; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (290 aa)
speHS-adenosylmethionine decarboxylase proenzyme, putative; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (172 aa)
ADZ69735.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1242 aa)
ADZ69831.1D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative. (414 aa)
cysESerine O-acetyltransferase, putative. (272 aa)
ADZ72758.1DNA methylase, C-5 cytosine-specific family. (418 aa)
ADZ70367.1O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase subfamily. (429 aa)
metCCystathionine beta-lyase protein. (394 aa)
ADZ70436.1Thiosulfate sulfurtransferase, Rhodanese-like protein. (280 aa)
ADZ70440.1Cysteine synthase A. (344 aa)
ADZ70562.1Putative Thiosulfate sulfurtransferase (Rhodanese-like protein). (284 aa)
ADZ70881.1Amidohydrolase:Amidohydrolase-like protein. (451 aa)
ADZ70892.1Amidohydrolase. (484 aa)
ADZ71019.1Modification methylase DdeI. (480 aa)
ADZ71082.1Homoserine dehydrogenase. (433 aa)
ilvEBranched-chain amino acid aminotransferase 1. (326 aa)
ADZ71200.1Methyltransferase protein. (318 aa)
ADZ71221.1Malate/L-sulfolactate dehydrogenase multifunction enzyme, putative; Belongs to the LDH2/MDH2 oxidoreductase family. (344 aa)
ADZ71247.1Rhodanese-like domain protein. (307 aa)
ADZ71401.1Aminotransferase, class IV superfamily. (285 aa)
metZO-succinylhomoserine (Thiol)-lyase protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (404 aa)
ADZ71912.1Putative glutamate--cysteine ligase protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (457 aa)
ADZ72008.1L-serine dehydratase protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa)
ADZ72539.1Phage DNA methyltransferase. (329 aa)
ADZ72604.1Methionine synthase, vitamin-B12 independent. (377 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (462 aa)
mdhMalate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
metKS-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (390 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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