(29 nodes) Arginine and proline metabolism network (Polymorphum gilvum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	ADZ69158.1	Hydantoinase B/oxoprolinase family protein. (595 aa)
	ADZ69159.1	5-oxoprolinase (ATP-hydrolyzing). (696 aa)
	ADZ69214.1	Creatininase subfamily. (269 aa)
	ADZ69224.1	Amidohydrolase family, putative. (449 aa)
	proC	Pyrroline-5-carboxylate reductase protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
	aatA	Aminotransferase, classes I and II superfamily. (399 aa)
	speE	Spermidine synthase 1; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (290 aa)
	speH	S-adenosylmethionine decarboxylase proenzyme, putative; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (172 aa)
	ADZ69717.1	FAD dependent oxidoreductase, putative. (439 aa)
	ADZ69739.1	Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (406 aa)
	ADZ69943.1	Putative oxidoreductase protein. (435 aa)
	ADZ70725.1	Aminotransferase, class IV superfamily. (287 aa)
	ADZ70886.1	Amidohydrolase family, putative. (425 aa)
	ADZ71064.1	Peptidase, M24 family. (423 aa)
	ADZ71087.1	Agmatinase, putative; Belongs to the arginase family. (319 aa)
	ADZ71422.1	Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (376 aa)
	ADZ71456.1	FAD dependent oxidoreductase, putative. (385 aa)
	ADZ71551.1	Creatininase. (272 aa)
	ADZ71574.1	FAD dependent oxidoreductase. (391 aa)
	ADZ71575.1	Ferredoxin. (84 aa)
	ADZ71576.1	BFD domain protein (2Fe-2S)-binding domain protein. (444 aa)
	ADZ71948.1	Aminotransferase, class III superfamily; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	ADZ71949.1	Aldehyde dehydrogenase 2B4; Belongs to the aldehyde dehydrogenase family. (491 aa)
	ADZ72122.1	Proline dehydrogenase family; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1042 aa)
	ADZ72249.1	5-oxoprolinase (ATP-hydrolyzing). (683 aa)
	ADZ72251.1	5-oxoprolinase (ATP-hydrolyzing). (578 aa)
	ADZ72261.1	Betaine-aldehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family. (475 aa)
	proB	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa)
	proA	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (426 aa)

Your Current Organism:

Polymorphum gilvum

NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADZ69158.1	ADZ69159.1	SL003B_0728	SL003B_0729	Hydantoinase B/oxoprolinase family protein.	5-oxoprolinase (ATP-hydrolyzing).	0.999
ADZ69158.1	ADZ69224.1	SL003B_0728	SL003B_0794	Hydantoinase B/oxoprolinase family protein.	Amidohydrolase family, putative.	0.900
ADZ69158.1	ADZ70886.1	SL003B_0728	SL003B_2461	Hydantoinase B/oxoprolinase family protein.	Amidohydrolase family, putative.	0.900
ADZ69158.1	ADZ72249.1	SL003B_0728	SL003B_3829	Hydantoinase B/oxoprolinase family protein.	5-oxoprolinase (ATP-hydrolyzing).	0.999
ADZ69158.1	ADZ72251.1	SL003B_0728	SL003B_3830	Hydantoinase B/oxoprolinase family protein.	5-oxoprolinase (ATP-hydrolyzing).	0.919
ADZ69159.1	ADZ69158.1	SL003B_0729	SL003B_0728	5-oxoprolinase (ATP-hydrolyzing).	Hydantoinase B/oxoprolinase family protein.	0.999
ADZ69159.1	ADZ69224.1	SL003B_0729	SL003B_0794	5-oxoprolinase (ATP-hydrolyzing).	Amidohydrolase family, putative.	0.900
ADZ69159.1	ADZ70886.1	SL003B_0729	SL003B_2461	5-oxoprolinase (ATP-hydrolyzing).	Amidohydrolase family, putative.	0.900
ADZ69159.1	ADZ72249.1	SL003B_0729	SL003B_3829	5-oxoprolinase (ATP-hydrolyzing).	5-oxoprolinase (ATP-hydrolyzing).	0.915
ADZ69159.1	ADZ72251.1	SL003B_0729	SL003B_3830	5-oxoprolinase (ATP-hydrolyzing).	5-oxoprolinase (ATP-hydrolyzing).	0.999
ADZ69214.1	ADZ69224.1	SL003B_0784	SL003B_0794	Creatininase subfamily.	Amidohydrolase family, putative.	0.963
ADZ69214.1	ADZ70886.1	SL003B_0784	SL003B_2461	Creatininase subfamily.	Amidohydrolase family, putative.	0.908
ADZ69214.1	ADZ71064.1	SL003B_0784	SL003B_2641	Creatininase subfamily.	Peptidase, M24 family.	0.901
ADZ69214.1	ADZ71551.1	SL003B_0784	SL003B_3129	Creatininase subfamily.	Creatininase.	0.971
ADZ69224.1	ADZ69158.1	SL003B_0794	SL003B_0728	Amidohydrolase family, putative.	Hydantoinase B/oxoprolinase family protein.	0.900
ADZ69224.1	ADZ69159.1	SL003B_0794	SL003B_0729	Amidohydrolase family, putative.	5-oxoprolinase (ATP-hydrolyzing).	0.900
ADZ69224.1	ADZ69214.1	SL003B_0794	SL003B_0784	Amidohydrolase family, putative.	Creatininase subfamily.	0.963
ADZ69224.1	ADZ70886.1	SL003B_0794	SL003B_2461	Amidohydrolase family, putative.	Amidohydrolase family, putative.	0.927
ADZ69224.1	ADZ71551.1	SL003B_0794	SL003B_3129	Amidohydrolase family, putative.	Creatininase.	0.927
ADZ69224.1	ADZ72249.1	SL003B_0794	SL003B_3829	Amidohydrolase family, putative.	5-oxoprolinase (ATP-hydrolyzing).	0.900

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