STRINGSTRING
ADZ68505.1 ADZ68505.1 acsA acsA ADZ68608.1 ADZ68608.1 glyA-3 glyA-3 ADZ68641.1 ADZ68641.1 ADZ68642.1 ADZ68642.1 ADZ68692.1 ADZ68692.1 ADZ68784.1 ADZ68784.1 ADZ68790.1 ADZ68790.1 ADZ68792.1 ADZ68792.1 acs acs ADZ68883.1 ADZ68883.1 purU purU ADZ69295.1 ADZ69295.1 ADZ69402.1 ADZ69402.1 gph gph cbbS cbbS rbcL rbcL ADZ69520.1 ADZ69520.1 fdnG fdnG ADZ69708.1 ADZ69708.1 fdxH fdxH ADZ69710.1 ADZ69710.1 ADZ69725.1 ADZ69725.1 eda eda ADZ70203.1 ADZ70203.1 ADZ70209.1 ADZ70209.1 ADZ70214.1 ADZ70214.1 gph1 gph1 ADZ70298.1 ADZ70298.1 glyA glyA amiF amiF glnA3 glnA3 ADZ70510.1 ADZ70510.1 gltA gltA ADZ70552.1 ADZ70552.1 fdsB fdsB fdsA fdsA fdsD fdsD ADZ70664.1 ADZ70664.1 ADZ70743.1 ADZ70743.1 ADZ70877.1 ADZ70877.1 ADZ70895.1 ADZ70895.1 ADZ70939.1 ADZ70939.1 gph-2 gph-2 ADZ71404.1 ADZ71404.1 mutA mutA glcB glcB ADZ71567.1 ADZ71567.1 ADZ71666.1 ADZ71666.1 ADZ71708.1 ADZ71708.1 ADZ71797.1 ADZ71797.1 gcvPA gcvPA gcvH gcvH ADZ71801.1 ADZ71801.1 ADZ71862.1 ADZ71862.1 ADZ71866.1 ADZ71866.1 ADZ71896.1 ADZ71896.1 ADZ71898.1 ADZ71898.1 ADZ71899.1 ADZ71899.1 ADZ71945.1 ADZ71945.1 ADZ71947.1 ADZ71947.1 ADZ71957.1 ADZ71957.1 ipuC ipuC kynB kynB ADZ72646.1 ADZ72646.1 mdh mdh ADZ72689.1 ADZ72689.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ68505.1D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative. (328 aa)
acsAAcetate-CoA ligase, AMP-dependent; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
ADZ68608.1Putative acetyl-coenzyme A synthetase (AcsA-like). (546 aa)
glyA-3Serine hydroxymethyltransferase. (439 aa)
ADZ68641.1Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
ADZ68642.1Acetoacetyl-CoA reductase subfamily. (242 aa)
ADZ68692.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
ADZ68784.1Dehydrogenase with MaoC-like domain/dehydrogenase with MaoC-like domain. (350 aa)
ADZ68790.1Crotonyl-CoA reductase, putative. (431 aa)
ADZ68792.1Methylmalonyl-CoA mutase MeaA-like protein. (660 aa)
acsAMP-dependent synthetase and ligase. (545 aa)
ADZ68883.1Acyl-CoA dehydrogenase, C-terminal domain protein. (562 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa)
ADZ69295.1Putative hydroxypyruvate reductase; Putative glycerate kinase. (431 aa)
ADZ69402.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (319 aa)
gphPhosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (228 aa)
cbbSRibulose bisphosphate carboxylase small chain. (129 aa)
rbcLRibulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (485 aa)
ADZ69520.1AMP-dependent synthetase and ligase. (593 aa)
fdnGFormate dehydrogenase, major subunit. (165 aa)
ADZ69708.1Formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (813 aa)
fdxHFormate dehydrogenase, beta subunit. (302 aa)
ADZ69710.1Formate dehydrogenase, gamma subunit. (222 aa)
ADZ69725.1Acetyl-CoA C-acyltransferase 8. (425 aa)
eda2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase subfamily. (212 aa)
ADZ70203.1Haloacid dehalogenase-like hydrolase, putative. (226 aa)
ADZ70209.1Carboxyl transferase domain, putative. (510 aa)
ADZ70214.1Propionyl-CoA carboxylase alpha chain. (670 aa)
gph1Hydrolase, haloacid dehalogenase-like family. (235 aa)
ADZ70298.1Alpha/beta hydrolase fold-3 domain protein. (283 aa)
glyASerine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (449 aa)
amiFFormamidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (339 aa)
glnA3Glutamine synthetase 1. (469 aa)
ADZ70510.1Lactoylglutathione lyase. (134 aa)
gltACitrate synthase, chromosomal; Belongs to the citrate synthase family. (430 aa)
ADZ70552.1ATP synthase subunit E. (157 aa)
fdsBNADH dehydrogenase (Quinone). (525 aa)
fdsAFormate dehydrogenase, alpha subunit protein. (959 aa)
fdsDFormate dehydrogenase protein, delta subunit. (77 aa)
ADZ70664.1HpcH/HpaI aldolase/citrate lyase family, putative; Belongs to the HpcH/HpaI aldolase family. (346 aa)
ADZ70743.1Dihydrolipoyl dehydrogenase. (480 aa)
ADZ70877.16-phosphogluconate dehydrogenase, NAD-binding protein. (298 aa)
ADZ70895.1Citrate synthase. (265 aa)
ADZ70939.1Acetyl-CoA C-acetyltransferase; Putative 3-ketoacyl-CoA thiolase (Fatty oxidation complex beta subunit) (Beta-ketothiolase) (Acetyl-CoA acyltransferase) (FadA-like); Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
gph-2Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (227 aa)
ADZ71404.1Methylmalonyl-CoA mutase N-terminal domain subfamily. (721 aa)
mutAMethylmalonyl-CoA mutase, small subunit. (663 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (720 aa)
ADZ71567.1Acetyl-CoA synthetase (Acetate-CoA ligase). (519 aa)
ADZ71666.1Acetyl-CoA C-acetyltransferase; Putative 3-ketoacyl-CoA thiolase (Fatty oxidation complex beta subunit) (Beta-ketothiolase) (Acetyl-CoA acyltransferase) (FadA-like); Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ADZ71708.1Haloacid dehalogenase-like hydrolase, putative. (248 aa)
ADZ71797.1Glycine dehydrogenase subunit 2. (530 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvHGlycine decarboxylase complex H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
ADZ71801.1Aminomethyltransferase. (379 aa)
ADZ71862.1Probable maoC-like dehydratase. (133 aa)
ADZ71866.1Dehydrogenase with MaoC-like domain. (150 aa)
ADZ71896.1Glycolate oxidase iron-sulfur subunit. (449 aa)
ADZ71898.1Glycolate oxidase subunits GlcE. (405 aa)
ADZ71899.1ATPase, E1-E2 type. (498 aa)
ADZ71945.1Glutamine synthetase, putative. (461 aa)
ADZ71947.1Glutamine synthetase, catalytic domain, putative. (464 aa)
ADZ71957.1Thiolase, N-terminal domain subfamily, putative; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
ipuCGlutamine synthetase, catalytic domain, putative. (455 aa)
kynBKynurenine formamidase, KynB; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (211 aa)
ADZ72646.1Dihydrolipoamide dehydrogenase protein. (467 aa)
mdhMalate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
ADZ72689.1Aminotransferase, class V superfamily. (393 aa)
Your Current Organism:
Polymorphum gilvum
NCBI taxonomy Id: 991905
Other names: P. gilvum SL003B-26A1, Polymorphum gilvum SL003B-26A1, Polymorphum gilvum str. SL003B-26A1, Polymorphum gilvum strain SL003B-26A1, proteobacterium SL003B-26A1
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