STRINGSTRING
DIMT1 DIMT1 PLAT PLAT GKN3P GKN3P ENSCHIP00000001541 ENSCHIP00000001541 ARMCX1 ARMCX1 GJA1 GJA1 HHIP HHIP HOXA5 HOXA5 SELE SELE ACTBL2 ACTBL2 MYL6B MYL6B BGN BGN GFOD2 GFOD2 LOC102176799 LOC102176799 RBFOX3 RBFOX3 P2RY2 P2RY2 LOC102175177 LOC102175177 CAMK2D CAMK2D HILPDA HILPDA MYB MYB KCNU1 KCNU1 GFOD1 GFOD1 MYH11 MYH11 AGT AGT THBD THBD MRPL1 MRPL1 DNAJC13 DNAJC13 COMMD6 COMMD6 AGTR1 AGTR1 POMK POMK EDN1 EDN1 CAPN8 CAPN8 CALCRL CALCRL TCTN1 TCTN1 CTHRC1 CTHRC1 GFM2 GFM2 NOS3 NOS3 ACTB ACTB TIE1 TIE1 PPP1R14A PPP1R14A SEC23IP SEC23IP SDR39U1 SDR39U1 TCF21 TCF21 PGM2 PGM2 REN REN MYLK MYLK ICAM1 ICAM1 LOC102180084 LOC102180084 RUNX2 RUNX2 ENSCHIP00000015612 ENSCHIP00000015612 KLHDC1 KLHDC1 KCNMB1 KCNMB1 TCEANC TCEANC MYL12A MYL12A RSL24D1 RSL24D1 CRISPLD1 CRISPLD1 INTS4 INTS4 RUNX1 RUNX1 HTR2A HTR2A LAS1L LAS1L ENTPD1 ENTPD1 PDE8A PDE8A ACTA2 ACTA2 DENND1A DENND1A ELN ELN CAPN2 CAPN2 ANGPT4 ANGPT4 KCNN3 KCNN3 SDC4 SDC4 ORMDL2 ORMDL2 ATP2A3 ATP2A3 LIN37 LIN37 ALB ALB PECAM1 PECAM1 CAV1 CAV1 BMPR2 BMPR2 PDZD11 PDZD11 STOML1 STOML1 KCNQ1 KCNQ1 SERPINE1 SERPINE1 MYL9 MYL9 FBN1 FBN1 PDSS1 PDSS1 LOC102169209 LOC102169209 NOX4 NOX4 LOC102174895 LOC102174895 TBC1D8B TBC1D8B CALD1 CALD1 APOE APOE DROSHA DROSHA KCNK9 KCNK9 POGK POGK RPS6KA3 RPS6KA3 GAPDH GAPDH RGS5 RGS5 CD47 CD47 LOC102177186 LOC102177186 CSK CSK WDR41 WDR41 CAMK2B CAMK2B PDE8B PDE8B EIF3K EIF3K PDE5A PDE5A ENOPH1 ENOPH1 RXFP1 RXFP1 SCPEP1 SCPEP1 LOC106503207 LOC106503207 ACTL8 ACTL8 ATP13A3 ATP13A3 FGF5 FGF5 CCN2 CCN2 CAMK2A CAMK2A ATP2A2 ATP2A2 SOX18 SOX18 C1QTNF3 C1QTNF3 HTR2B HTR2B JUP JUP NME6 NME6 APP APP ACTG1 ACTG1 KCNK3 KCNK3 DEPDC7 DEPDC7 MSTO1 MSTO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (318 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (565 aa)
GKN3PGastrokine 3, pseudogene. (181 aa)
ENSCHIP00000001541PDZ domain-containing protein. (111 aa)
ARMCX1Armadillo repeat containing X-linked 1. (453 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
HHIPHedgehog interacting protein. (701 aa)
HOXA5Homeobox A5. (270 aa)
SELESelectin E. (487 aa)
ACTBL2Actin beta like 2. (376 aa)
MYL6BMyosin light chain 6B. (211 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa)
GFOD2Glucose-fructose oxidoreductase domain containing 2. (385 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
RBFOX3RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (373 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
LOC102175177Uncharacterized protein. (740 aa)
CAMK2DProtein kinase domain-containing protein. (532 aa)
HILPDAHypoxia inducible lipid droplet associated. (71 aa)
MYBMYB proto-oncogene, transcription factor. (640 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1143 aa)
GFOD1Glucose-fructose oxidoreductase domain containing 1. (429 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
AGTAngiotensinogen; Belongs to the serpin family. (476 aa)
THBDThrombomodulin. (578 aa)
MRPL1Uncharacterized protein. (321 aa)
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2243 aa)
COMMD6COMM domain-containing protein. (110 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
POMKProtein O-mannose kinase. (350 aa)
EDN1Endothelin 1. (202 aa)
CAPN8Calpain 8; Belongs to the peptidase C2 family. (719 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
TCTN1Tectonic family member 1. (592 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
GFM2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (777 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
ACTBUncharacterized protein. (375 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
PPP1R14AProtein phosphatase 1 regulatory inhibitor subunit 14A. (149 aa)
SEC23IPSEC23 interacting protein. (1006 aa)
SDR39U1Short chain dehydrogenase/reductase family 39U member 1. (304 aa)
TCF21Transcription factor 21. (179 aa)
PGM2Phosphoglucomutase 2. (629 aa)
RENRenin; Belongs to the peptidase A1 family. (403 aa)
MYLKMyosin light chain kinase. (1887 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
LOC102180084Uncharacterized protein; Belongs to the actin family. (319 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
ENSCHIP00000015612Uncharacterized protein. (289 aa)
KLHDC1Kelch domain containing 1. (406 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (394 aa)
MYL12AMyosin light chain 12A. (178 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
INTS4Integrator complex subunit 4. (964 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (453 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
LAS1LLAS1 like, ribosome biogenesis factor. (757 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (517 aa)
PDE8APhosphodiesterase. (832 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
DENND1ADENN domain containing 1A. (1024 aa)
ELNUncharacterized protein. (504 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
ANGPT4Angiopoietin 4. (498 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (713 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa)
LIN37Lin-37 DREAM MuvB core complex component. (240 aa)
ALBSerum albumin. (608 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (739 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PDZD11PDZ domain-containing protein. (140 aa)
STOML1Stomatin like 1. (398 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
MYL9Myosin light chain 9. (172 aa)
FBN1Fibrillin 1. (2860 aa)
PDSS1Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (429 aa)
LOC102169209Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (355 aa)
NOX4NADPH oxidase 4. (578 aa)
LOC102174895Uncharacterized protein. (735 aa)
TBC1D8BTBC1 domain family member 8B. (1120 aa)
CALD1Caldesmon 1. (535 aa)
APOEApolipoprotein E. (326 aa)
DROSHADrosha ribonuclease III. (1371 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
POGKPogo transposable element derived with KRAB domain. (604 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
RGS5Regulator of G protein signaling 5. (181 aa)
CD47CD47 molecule. (321 aa)
LOC102177186Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
CSKTyrosine-protein kinase. (450 aa)
WDR41WD repeat domain 41. (459 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (542 aa)
PDE8BPhosphodiesterase. (885 aa)
EIF3KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
PDE5APhosphodiesterase. (865 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
RXFP1Relaxin family peptide receptor 1. (763 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (458 aa)
LOC106503207Angiotensin-converting enzyme. (722 aa)
ACTL8Actin like 8; Belongs to the actin family. (389 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1256 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
CCN2Cellular communication network factor 2. (349 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1026 aa)
SOX18SRY-box transcription factor 18. (393 aa)
C1QTNF3C1q domain-containing protein. (319 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
JUPJunction plakoglobin. (745 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
APPAmyloid beta precursor protein. (770 aa)
ACTG1Actin gamma 1. (376 aa)
KCNK3Potassium channel subfamily K member. (399 aa)
DEPDC7DEP domain containing 7. (511 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (572 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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