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| | RPL4 | Ribos_L4_asso_C domain-containing protein. (434 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa) |
| | ATP6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) |
| | ENSCHIP00000000289 | Uncharacterized protein. (93 aa) |
| | ENSCHIP00000000375 | Ribos_L4_asso_C domain-containing protein. (362 aa) |
| | EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (120 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | LOC102189615 | Galectin. (186 aa) |
| | SNRNP25 | Small nuclear ribonucleoprotein U11/U12 subunit 25. (123 aa) |
| | ENSCHIP00000001287 | Uncharacterized protein. (70 aa) |
| | MUC13 | Uncharacterized protein. (679 aa) |
| | H1-0 | H1 histone family member 0. (194 aa) |
| | LIN7A | Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa) |
| | TMEM54 | Transmembrane protein 54. (226 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | ACTBL2 | Actin beta like 2. (376 aa) |
| | LOC102191395 | FAD-binding PCMH-type domain-containing protein. (479 aa) |
| | VWA5B2 | Von Willebrand factor A domain containing 5B2. (1254 aa) |
| | ENSCHIP00000003756 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (72 aa) |
| | DDI1 | DNA damage inducible 1 homolog 1. (459 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (419 aa) |
| | ELP6 | Elongator acetyltransferase complex subunit 6. (266 aa) |
| | MEPCE | Methylphosphate capping enzyme. (687 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | DHRS3 | Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | ENSCHIP00000004646 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (124 aa) |
| | NRIP1 | Nuclear receptor interacting protein 1. (1156 aa) |
| | LOC102176799 | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | BEST2 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (512 aa) |
| | ZG16 | Zymogen granule protein 16. (167 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (933 aa) |
| | LOC102184087 | Galectin. (342 aa) |
| | CCDC62 | Uncharacterized protein. (396 aa) |
| | TRMO | tRNA methyltransferase O. (436 aa) |
| | FAM3D | Family with sequence similarity 3 member D. (223 aa) |
| | EDEM2 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa) |
| | TOR4A | Torsin family 4 member A. (406 aa) |
| | PLA2G12B | Phospholipase A2 group XIIB. (195 aa) |
| | TMC4 | Transmembrane channel-like protein. (684 aa) |
| | FAU | Ubiquitin-like domain-containing protein. (81 aa) |
| | PPP1R14D | Uncharacterized protein. (144 aa) |
| | PCDH18 | Protocadherin 18. (1134 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (116 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa) |
| | PFDN1 | Prefoldin subunit 1. (122 aa) |
| | TRAPPC11 | Trafficking protein particle complex 11. (1159 aa) |
| | LOC102190770 | Ribos_L4_asso_C domain-containing protein. (406 aa) |
| | AQP8 | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (490 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | TRAPPC9 | Trafficking protein particle complex 9. (1008 aa) |
| | HAUS7 | HAUS augmin like complex subunit 7. (366 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | SLC19A2 | Solute carrier family 19 member 2. (495 aa) |
| | GALNT12 | Polypeptide N-acetylgalactosaminyltransferase. (579 aa) |
| | PGAP3 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (319 aa) |
| | ACTB | Uncharacterized protein. (375 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (275 aa) |
| | RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) |
| | CXXC1 | CXXC finger protein 1. (663 aa) |
| | CYB5R1 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa) |
| | SAAL1 | Serum amyloid A like 1. (473 aa) |
| | SETDB2 | SET domain bifurcated histone lysine methyltransferase 2. (700 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). (367 aa) |
| | LMO2 | LIM domain only 2. (224 aa) |
| | REG4 | Regenerating family member 4. (158 aa) |
| | RGS1 | Regulator of G protein signaling 1. (209 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (888 aa) |
| | FXYD2 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (75 aa) |
| | LOC102185870 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa) |
| | ZNF217 | Zinc finger protein 217. (963 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa) |
| | TMEM104 | Transmembrane protein 104. (495 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | FAM83E | Family with sequence similarity 83 member E. (494 aa) |
| | ENSCHIP00000015207 | Ubiquitin-like domain-containing protein. (78 aa) |
| | LOC102180084 | Uncharacterized protein; Belongs to the actin family. (319 aa) |
| | TRABD2B | TraB domain containing 2B. (521 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa) |
| | LPCAT4 | Lysophosphatidylcholine acyltransferase 4. (524 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | IL10 | Interleukin 10. (177 aa) |
| | SPDEF | SAM pointed domain containing ETS transcription factor. (330 aa) |
| | LOC102185396 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (353 aa) |
| | FERMT1 | Fermitin family member 1. (679 aa) |
| | GPX2 | Glutathione peroxidase 2. (170 aa) |
| | ENSCHIP00000017727 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (59 aa) |
| | C12orf49 | Chromosome 12 open reading frame 49. (214 aa) |
| | LOC106503912 | Galectin. (116 aa) |
| | NLRX1 | NLR family member X1. (973 aa) |
| | ENSCHIP00000018982 | Uncharacterized protein. (248 aa) |
| | MYH7B | Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa) |
| | POLR1A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1703 aa) |
| | LOC102187672 | Galectin. (185 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | PRSS8 | Serine protease 8; Belongs to the peptidase S1 family. (343 aa) |
| | CD177 | CD177 molecule. (441 aa) |
| | NOP2 | SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (823 aa) |
| | LOC102170214 | Ribos_L4_asso_C domain-containing protein. (405 aa) |
| | VSIG2 | V-set and immunoglobulin domain containing 2. (328 aa) |
| | WDR55 | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (382 aa) |
| | LOC106501744 | Ribos_L4_asso_C domain-containing protein. (369 aa) |
| | TMIGD1 | Transmembrane and immunoglobulin domain containing 1. (261 aa) |
| | PCGF2 | Polycomb group ring finger 2. (344 aa) |
| | RAB25 | RAB25, member RAS oncogene family. (213 aa) |
| | LOC102168547 | Beta-2-microglobulin. (124 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | LYPD8 | Uncharacterized protein. (230 aa) |
| | AOC1 | Amine oxidase. (755 aa) |
| | EIF4EBP1 | Uncharacterized protein. (118 aa) |
| | PTPN3 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (905 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1187 aa) |
| | DUS1L | Dihydrouridine synthase 1 like. (511 aa) |
| | COLCA2 | Uncharacterized protein. (169 aa) |
| | LOC108638256 | Galectin. (243 aa) |
| | HTR3C | 5-hydroxytryptamine receptor 3C. (402 aa) |
| | CCHCR1 | Coiled-coil alpha-helical rod protein 1. (866 aa) |
| | LOC102179414 | Uncharacterized protein. (81 aa) |
| | POF1B | POF1B actin binding protein. (612 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CHP2 | Calcineurin like EF-hand protein 2. (196 aa) |
| | TMEM45B | Transmembrane protein 45B. (276 aa) |
| | GNPNAT1 | Glucosamine 6-phosphate N-acetyltransferase. (184 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | FBXL12 | F-box and leucine rich repeat protein 12. (326 aa) |
| | CA7 | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1905 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | ERAL1 | Era like 12S mitochondrial rRNA chaperone 1. (437 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | GSDMB | Gasdermin B. (432 aa) |
| | DROSHA | Drosha ribonuclease III. (1371 aa) |
| | PDZD3 | PDZ domain containing 3. (471 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | ANKZF1 | Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (720 aa) |
| | ETV4 | ETS variant 4. (490 aa) |
| | HEBP2 | Heme binding protein 2. (205 aa) |
| | CRADD | CASP2 and RIPK1 domain containing adaptor with death domain. (199 aa) |
| | BPIFB3 | BPI fold containing family B member 3. (480 aa) |
| | RNF111 | Ring finger protein 111. (986 aa) |
| | VWA5B1 | Von Willebrand factor A domain containing 5B1. (1183 aa) |
| | ENSCHIP00000028548 | Ribos_L4_asso_C domain-containing protein. (373 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (274 aa) |
| | CFL1 | Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (389 aa) |
| | RSAD1 | Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa) |
| | GAL | Galanin and GMAP prepropeptide. (123 aa) |
| | TMEFF2 | Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa) |
| | PLCD3 | Phosphoinositide phospholipase C. (782 aa) |
| | PYY | Peptide YY. (87 aa) |
| | TMBIM1 | Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (255 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (449 aa) |
| | ABCF2 | Uncharacterized protein. (625 aa) |
| | DEF8 | Differentially expressed in FDCP 8 homolog. (447 aa) |
| | SLC16A9 | Solute carrier family 16 member 9. (513 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa) |
| | ENSCHIP00000031738 | Galectin. (224 aa) |
| | SMAGP | Small cell adhesion glycoprotein. (96 aa) |
| | LOC102183269 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa) |
| | JCHAIN | Joining chain of multimeric IgA and IgM. (158 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | PRDM10 | PR/SET domain 10. (1150 aa) |
| | ACTG1 | Actin gamma 1. (376 aa) |
| | NOP14 | NOP14 nucleolar protein. (868 aa) |
| | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa) |
| | MTIF3 | Uncharacterized protein. (373 aa) |
| | MARS1 | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (893 aa) |
| | SLC12A2 | Solute carrier family 12 member 2. (1202 aa) |
| | SLC26A3 | Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa) |
| | ENSCHIP00000033815 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (85 aa) |
