STRINGSTRING
DNAJC24 DNAJC24 SAV1 SAV1 OGA OGA ENSCHIP00000009843 ENSCHIP00000009843 IL6 IL6 THAP7 THAP7 FGFRL1 FGFRL1 LRRC74B LRRC74B FJX1 FJX1 TNFSF13B TNFSF13B MCOLN1 MCOLN1 HBM HBM ENSCHIP00000002714 ENSCHIP00000002714 FLT3 FLT3 POLR2H POLR2H CD247 CD247 LRRC74A LRRC74A APEH APEH AFF1 AFF1 LOC102186117 LOC102186117 TNF TNF BANF2 BANF2 PIK3IP1 PIK3IP1 AQP5 AQP5 KLHDC4 KLHDC4 ENSCHIP00000006185 ENSCHIP00000006185 RBL1 RBL1 MDM4 MDM4 CD4 CD4 DOCK10 DOCK10 BCO2 BCO2 ALG14 ALG14 NUDT14 NUDT14 SAMD8 SAMD8 IZUMO4 IZUMO4 KLRK1 KLRK1 SERINC3 SERINC3 PTK7 PTK7 DOCK9 DOCK9 ENSCHIP00000033677 ENSCHIP00000033677 LATS1 LATS1 MARCHF4 MARCHF4 FIP1L1 FIP1L1 GOLGA1 GOLGA1 DOCK11 DOCK11 RBL2 RBL2 CNTN6 CNTN6 IL1B IL1B TOM1 TOM1 SLC22A5 SLC22A5 NTRK1 NTRK1 CRBN CRBN LOC108633874 LOC108633874 NUDT4 NUDT4 BANF1 BANF1 AGXT2 AGXT2 DTX4 DTX4 CST7 CST7 UBP1 UBP1 SLC22A4 SLC22A4 TF TF MAP2K7 MAP2K7 LOC102170799 LOC102170799 NPTN NPTN ITGA9 ITGA9 DLAT DLAT FGFR1OP2 FGFR1OP2 MLN MLN LOC102190507 LOC102190507 CACNG7 CACNG7 ILK ILK CACNG5 CACNG5 ENSCHIP00000016631 ENSCHIP00000016631 SLC38A4 SLC38A4 BCL2 BCL2 FAM20B FAM20B BRD9 BRD9 RBM22 RBM22 TNFSF11 TNFSF11 SLC22A1 SLC22A1 RARA RARA DOCK8 DOCK8 ITGA2B ITGA2B BPIFA2 BPIFA2 RUNX1T1 RUNX1T1 CEP83 CEP83 ITIH4 ITIH4 YY1 YY1 SHMT1 SHMT1 LOC108633873 LOC108633873
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNAJC24DnaJ heat shock protein family (Hsp40) member C24. (148 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
OGAO-GlcNAcase. (916 aa)
ENSCHIP000000098432-oxoacid_dh domain-containing protein. (521 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
THAP7THAP domain containing 7. (308 aa)
FGFRL1Fibroblast growth factor receptor like 1. (526 aa)
LRRC74BLeucine rich repeat containing 74B. (374 aa)
FJX1Four-jointed box kinase 1. (437 aa)
TNFSF13BTumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa)
MCOLN1Mucolipin 1. (580 aa)
HBMHemoglobin subunit mu; Belongs to the globin family. (145 aa)
ENSCHIP00000002714Uncharacterized protein. (81 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
CD247CD247 molecule. (166 aa)
LRRC74ALeucine rich repeat containing 74A. (494 aa)
APEHAcylaminoacyl-peptide hydrolase. (730 aa)
AFF1AF4/FMR2 family member 1. (1227 aa)
LOC102186117FAD-binding PCMH-type domain-containing protein. (441 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
BANF2Barrier to autointegration factor 2. (90 aa)
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (261 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
KLHDC4Kelch domain containing 4. (568 aa)
ENSCHIP00000006185Uncharacterized protein. (76 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
CD4CD4 molecule. (455 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2146 aa)
BCO2Beta-carotene oxygenase 2. (575 aa)
ALG14ALG14 UDP-N-acetylglucosaminyltransferase subunit. (173 aa)
NUDT14Nudix hydrolase 14. (222 aa)
SAMD8Sterile alpha motif domain containing 8. (478 aa)
IZUMO4IZUMO family member 4. (212 aa)
KLRK1Killer cell lectin like receptor K1. (208 aa)
SERINC3Serine incorporator 3. (472 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2064 aa)
ENSCHIP00000033677RanBP2-type domain-containing protein. (336 aa)
LATS1Large tumor suppressor kinase 1. (1145 aa)
MARCHF4Membrane associated ring-CH-type finger 4. (409 aa)
FIP1L1Fip1 domain-containing protein. (568 aa)
GOLGA1Golgin A1. (768 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2087 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
CNTN6Contactin 6. (1032 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (510 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
CRBNCereblon. (444 aa)
LOC108633874Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family. (142 aa)
NUDT4Nudix hydrolase domain-containing protein. (180 aa)
BANF1Barrier to autointegration factor 1. (89 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
CST7Cystatin F. (134 aa)
UBP1Upstream binding protein 1. (538 aa)
SLC22A4Solute carrier family 22 member 4. (553 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (558 aa)
LOC102170799BPI1 domain-containing protein. (274 aa)
NPTNNeuroplastin. (361 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
FGFR1OP2FGFR1 oncogene partner 2. (253 aa)
MLNMotilin. (115 aa)
LOC102190507Uncharacterized protein. (139 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
ILKIntegrin linked kinase. (452 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
ENSCHIP00000016631HARE-HTH domain-containing protein. (59 aa)
SLC38A4Solute carrier family 38 member 4. (547 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
FAM20BFAM20B glycosaminoglycan xylosylkinase. (409 aa)
BRD9Bromodomain containing 9. (577 aa)
RBM22RNA binding motif protein 22. (420 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (316 aa)
SLC22A1Solute carrier family 22 member 1. (563 aa)
RARARetinoic acid receptor alpha. (462 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2091 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1030 aa)
BPIFA2BPI1 domain-containing protein. (259 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (603 aa)
CEP83Centrosomal protein 83. (700 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (909 aa)
YY1YY1 transcription factor. (415 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
LOC108633873GLOBIN domain-containing protein; Belongs to the globin family. (142 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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