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COX1 COX1 SPINK7 SPINK7 SCNM1 SCNM1 TAGLN TAGLN LOC102180084 LOC102180084 CAAP1 CAAP1 CLDND1 CLDND1 VBP1 VBP1 ATP4A ATP4A EFCAB7 EFCAB7 IL36A IL36A LOC102186941 LOC102186941 GAPDH GAPDH ATP12A ATP12A CAPN14 CAPN14 USP40 USP40 EPC2 EPC2 CLDN18 CLDN18 ACTL8 ACTL8 MFSD1 MFSD1 ZNF557 ZNF557 ACTG1 ACTG1 ACTB ACTB PPWD1 PPWD1 PPL PPL EIF3H EIF3H FAM76A FAM76A RNF19B RNF19B LOC102176799 LOC102176799 NRIP1 NRIP1 DDI1 DDI1 ACTBL2 ACTBL2 LOC102185728 LOC102185728 MUC13 MUC13 TMPRSS11A TMPRSS11A CYTB CYTB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
SPINK7Serine peptidase inhibitor, Kazal type 7 (putative). (80 aa)
SCNM1Sodium channel modifier 1. (230 aa)
TAGLNTransgelin; Belongs to the calponin family. (201 aa)
LOC102180084Uncharacterized protein; Belongs to the actin family. (319 aa)
CAAP1Caspase activity and apoptosis inhibitor 1. (362 aa)
CLDND1Claudin domain containing 1. (276 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
EFCAB7EF-hand calcium binding domain 7. (629 aa)
IL36AInterleukin-1. (176 aa)
LOC102186941Transmembrane protease serine; Belongs to the peptidase S1 family. (418 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1074 aa)
CAPN14Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (442 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1234 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
ACTL8Actin like 8; Belongs to the actin family. (389 aa)
MFSD1Major facilitator superfamily domain containing 1. (468 aa)
ZNF557Uncharacterized protein. (402 aa)
ACTG1Actin gamma 1. (376 aa)
ACTBUncharacterized protein. (375 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (720 aa)
PPLPeriplakin. (1755 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
FAM76AFamily with sequence similarity 76 member A. (307 aa)
RNF19BRBR-type E3 ubiquitin transferase. (735 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
NRIP1Nuclear receptor interacting protein 1. (1156 aa)
DDI1DNA damage inducible 1 homolog 1. (459 aa)
ACTBL2Actin beta like 2. (376 aa)
LOC102185728Transmembrane protease serine; Belongs to the peptidase S1 family. (416 aa)
MUC13Uncharacterized protein. (679 aa)
TMPRSS11ATransmembrane protease serine; Belongs to the peptidase S1 family. (417 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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