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| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa) |
| | SYCN | Syncollin. (134 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (480 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | NME6 | Nucleoside diphosphate kinase. (186 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | TNS4 | Tensin 4. (694 aa) |
| | ACTG1 | Actin gamma 1. (376 aa) |
| | KCNK3 | Potassium channel subfamily K member. (399 aa) |
| | STAB2 | Stabilin 2. (2530 aa) |
| | ITGA10 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1178 aa) |
| | DEPDC7 | DEP domain containing 7. (511 aa) |
| | MSTO1 | Misato mitochondrial distribution and morphology regulator 1. (572 aa) |
| | REN | Renin; Belongs to the peptidase A1 family. (403 aa) |
| | MYLK | Myosin light chain kinase. (1887 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (532 aa) |
| | LOC102180495 | Tr-type G domain-containing protein. (435 aa) |
| | LOC102180084 | Uncharacterized protein; Belongs to the actin family. (319 aa) |
| | RUNX2 | RUNX family transcription factor 2. (585 aa) |
| | ENSCHIP00000015612 | Uncharacterized protein. (289 aa) |
| | KLHDC1 | Kelch domain containing 1. (406 aa) |
| | KCNMB1 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa) |
| | TCEANC | Transcription elongation factor A N-terminal and central domain containing. (394 aa) |
| | MYL12A | Myosin light chain 12A. (178 aa) |
| | RSL24D1 | Ribosomal L24 domain containing 1. (163 aa) |
| | ASGR1 | Asialoglycoprotein receptor 1. (286 aa) |
| | EEF1A2 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa) |
| | CRISPLD1 | Cysteine rich secretory protein LCCL domain containing 1. (500 aa) |
| | INTS4 | Integrator complex subunit 4. (964 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (453 aa) |
| | ENSCHIP00000016659 | Tr-type G domain-containing protein. (120 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1766 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | LAS1L | LAS1 like, ribosome biogenesis factor. (757 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (517 aa) |
| | PDE8A | Phosphodiesterase. (832 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (377 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (337 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (360 aa) |
| | DENND1A | DENN domain containing 1A. (1024 aa) |
| | ELN | Uncharacterized protein. (504 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (700 aa) |
| | ANGPT4 | Angiopoietin 4. (498 aa) |
| | KCNN3 | Potassium calcium-activated channel subfamily N member 3. (713 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa) |
| | COL6A3 | Collagen type VI alpha 3 chain. (3111 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | FAM13C | Family with sequence similarity 13 member C. (601 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (240 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | ALB | Serum albumin. (608 aa) |
| | PECAM1 | Platelet and endothelial cell adhesion molecule 1. (739 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (584 aa) |
| | PRRC2B | Proline rich coiled-coil 2B. (1467 aa) |
| | SH2D2A | SH2 domain containing 2A. (420 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | PDZD11 | PDZ domain-containing protein. (140 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (335 aa) |
| | AFM | Afamin. (604 aa) |
| | STOML1 | Stomatin like 1. (398 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) |
| | SPARC | Osteonectin. (303 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | GCG | Glucagon. (180 aa) |
| | FBN1 | Fibrillin 1. (2860 aa) |
| | PDSS1 | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (429 aa) |
| | P4HA3 | Prolyl 4-hydroxylase subunit alpha 3. (544 aa) |
| | LOC102169209 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (355 aa) |
| | NOX4 | NADPH oxidase 4. (578 aa) |
| | EPHB4 | EPH receptor B4. (993 aa) |
| | FN1 | Fibronectin 1. (2478 aa) |
| | LOC102174895 | Uncharacterized protein. (735 aa) |
| | HCN2 | Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (904 aa) |
| | GOLGA3 | Golgin A3. (1496 aa) |
| | TBC1D8B | TBC1 domain family member 8B. (1120 aa) |
| | CALD1 | Caldesmon 1. (535 aa) |
| | APOE | Apolipoprotein E. (326 aa) |
| | DROSHA | Drosha ribonuclease III. (1371 aa) |
| | KCNK9 | Potassium channel subfamily K member. (374 aa) |
| | POGK | Pogo transposable element derived with KRAB domain. (604 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | RGS5 | Regulator of G protein signaling 5. (181 aa) |
| | CD47 | CD47 molecule. (321 aa) |
| | LOC102177186 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | ZRANB1 | Zinc finger RANBP2-type containing 1. (734 aa) |
| | WDR41 | WD repeat domain 41. (459 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (542 aa) |
| | PDE8B | Phosphodiesterase. (885 aa) |
| | EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) |
| | PDE5A | Phosphodiesterase. (865 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (763 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | LUM | Lumican. (342 aa) |
| | SCPEP1 | Carboxypeptidase; Belongs to the peptidase S10 family. (458 aa) |
| | FAM124B | Family with sequence similarity 124 member B. (461 aa) |
| | ACTBL2 | Actin beta like 2. (376 aa) |
| | MYL6B | Myosin light chain 6B. (211 aa) |
| | BGN | Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa) |
| | DIMT1 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (318 aa) |
| | ENSCHIP00000003677 | Tr-type G domain-containing protein. (438 aa) |
| | LOC108636537 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (441 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | GFOD2 | Glucose-fructose oxidoreductase domain containing 2. (385 aa) |
| | CHST1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | SKIL | c-SKI_SMAD_bind domain-containing protein. (684 aa) |
| | LOC102176799 | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | SELE | Selectin E. (487 aa) |
| | ECSCR | Uncharacterized protein. (253 aa) |
| | HOXA5 | Homeobox A5. (270 aa) |
| | HHIP | Hedgehog interacting protein. (701 aa) |
| | FAP | Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa) |
| | GJA1 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa) |
| | ARMCX1 | Armadillo repeat containing X-linked 1. (453 aa) |
| | ENSCHIP00000001541 | PDZ domain-containing protein. (111 aa) |
| | GKN3P | Gastrokine 3, pseudogene. (181 aa) |
| | VWA2 | Von Willebrand factor A domain containing 2. (775 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (565 aa) |
| | ENSCHIP00000000105 | c-SKI_SMAD_bind domain-containing protein. (664 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa) |
| | DGKE | Diacylglycerol kinase. (564 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | LOC106503207 | Angiotensin-converting enzyme. (722 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | SELP | Selectin P. (771 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (389 aa) |
| | HCN1 | Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (877 aa) |
| | ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1256 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | TIMP2 | TIMP metallopeptidase inhibitor 2. (220 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (291 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | LYVE1 | Lymphatic vessel endothelial hyaluronan receptor 1. (322 aa) |
| | RBFOX3 | RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (373 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | P2RY2 | Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | LOC102175177 | Uncharacterized protein. (740 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (532 aa) |
| | HILPDA | Hypoxia inducible lipid droplet associated. (71 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (640 aa) |
| | EEF1A1 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa) |
| | KCNU1 | Potassium calcium-activated channel subfamily U member 1. (1143 aa) |
| | GFOD1 | Glucose-fructose oxidoreductase domain containing 1. (429 aa) |
| | MYH11 | Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (476 aa) |
| | THBD | Thrombomodulin. (578 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa) |
| | MRPL1 | Uncharacterized protein. (321 aa) |
| | DNAJC13 | DnaJ heat shock protein family (Hsp40) member C13. (2243 aa) |
| | HCN4 | Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa) |
| | COMMD6 | COMM domain-containing protein. (110 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | POMK | Protein O-mannose kinase. (350 aa) |
| | EDN1 | Endothelin 1. (202 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa) |
| | CAPN8 | Calpain 8; Belongs to the peptidase C2 family. (719 aa) |
| | CALCRL | Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa) |
| | ARHGEF38 | Rho guanine nucleotide exchange factor 38. (778 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) |
| | CSGALNACT2 | Hexosyltransferase. (540 aa) |
| | GPIHBP1 | Uncharacterized protein. (92 aa) |
| | TCTN1 | Tectonic family member 1. (592 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | GFM2 | Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (777 aa) |
| | VWF | Von Willebrand factor. (2819 aa) |
| | TACC2 | Transforming acidic coiled-coil containing protein 2. (2904 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa) |
| | ACTB | Uncharacterized protein. (375 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1365 aa) |
| | HMGA2 | Uncharacterized protein. (104 aa) |
| | PPP1R14A | Protein phosphatase 1 regulatory inhibitor subunit 14A. (149 aa) |
| | SEC23IP | SEC23 interacting protein. (1006 aa) |
| | LAMC1 | Laminin subunit gamma 1. (1608 aa) |
| | SDR39U1 | Short chain dehydrogenase/reductase family 39U member 1. (304 aa) |
| | TMEM225B | Transmembrane protein 225B. (226 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). (367 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | PGM2 | Phosphoglucomutase 2. (629 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1026 aa) |
| | SOX18 | SRY-box transcription factor 18. (393 aa) |
| | LOC102172606 | Uncharacterized protein. (338 aa) |
| | C1QTNF3 | C1q domain-containing protein. (319 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (955 aa) |
