STRINGSTRING
SIAH1 SIAH1 ND4 ND4 CACNA1F CACNA1F SAG SAG FGF14 FGF14 RGS20 RGS20 ACTBL2 ACTBL2 RAB27A RAB27A DDI1 DDI1 ENSCHIP00000003813 ENSCHIP00000003813 TMEM215 TMEM215 IMPG1 IMPG1 CCDC9 CCDC9 DHRS3 DHRS3 GABRR1 GABRR1 NRIP1 NRIP1 LOC102176799 LOC102176799 LRIT1 LRIT1 DEPDC1 DEPDC1 TTR TTR CLRN1 CLRN1 IMPG2 IMPG2 VAX2 VAX2 ATOH8 ATOH8 CDH3 CDH3 RBP3 RBP3 GRK7 GRK7 ZC3H11A ZC3H11A TMEM17 TMEM17 CNGB3 CNGB3 GABRR2 GABRR2 ACTB ACTB NDP NDP ARRB1 ARRB1 CNGA1 CNGA1 GJA10 GJA10 ZPR1 ZPR1 FRMPD2 FRMPD2 NR2E3 NR2E3 VSX2 VSX2 SAMD7 SAMD7 LOC102175286 LOC102175286 FGF12 FGF12 ARRB2 ARRB2 LOC102180084 LOC102180084 PDE6G PDE6G ANKRD33 ANKRD33 CNGB1 CNGB1 CYP26B1 CYP26B1 RLBP1 RLBP1 PDE6A PDE6A RHO RHO CALB2 CALB2 LOC108634933 LOC108634933 ARR3 ARR3 LEUTX LEUTX SHROOM2 SHROOM2 STARD3 STARD3 PDE6B PDE6B SLC45A2 SLC45A2 CLCN4 CLCN4 SPARC SPARC CALB1 CALB1 ABCA4 ABCA4 ANKRD33B ANKRD33B ATP1B2 ATP1B2 PDZD3 PDZD3 EFR3A EFR3A GAPDH GAPDH FAM189A1 FAM189A1 GNGT2 GNGT2 CRX CRX CRB3 CRB3 SCAPER SCAPER RPE65 RPE65 NCAN NCAN ANAPC4 ANAPC4 NYX NYX GFAP GFAP OLFML2A OLFML2A CISD2 CISD2 AGL AGL KIFC3 KIFC3 XRCC2 XRCC2 CFL1 CFL1 ACTL8 ACTL8 RGR RGR SLC6A6 SLC6A6 PDGFRB PDGFRB RP1 RP1 GNAT1 GNAT1 NRL NRL RGS16 RGS16 MEGF10 MEGF10 PDGFB PDGFB RORB RORB CERKL CERKL PDE6H PDE6H RPGRIP1 RPGRIP1 RCVRN RCVRN APP APP TNS4 TNS4 ACTG1 ACTG1 RBPMS RBPMS OLFML2B OLFML2B GOLGB1 GOLGB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1929 aa)
SAGS-antigen visual arrestin. (418 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
RGS20Regulator of G protein signaling 20. (374 aa)
ACTBL2Actin beta like 2. (376 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
DDI1DNA damage inducible 1 homolog 1. (459 aa)
ENSCHIP00000003813Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (551 aa)
TMEM215Transmembrane protein 215. (235 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (781 aa)
CCDC9Coiled-coil domain containing 9. (513 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
NRIP1Nuclear receptor interacting protein 1. (1156 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (622 aa)
DEPDC1DEP domain containing 1. (812 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
CLRN1Clarin 1. (232 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1207 aa)
VAX2Ventral anterior homeobox 2. (286 aa)
ATOH8Atonal bHLH transcription factor 8. (315 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (831 aa)
RBP3Retinol binding protein 3. (1286 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (552 aa)
ZC3H11AUncharacterized protein. (786 aa)
TMEM17Transmembrane protein 17. (198 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (767 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
ACTBUncharacterized protein. (375 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
ARRB1Arrestin beta 1. (418 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (676 aa)
GJA10Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (522 aa)
ZPR1ZPR1 zinc finger. (459 aa)
FRMPD2FERM and PDZ domain containing 2. (1379 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (411 aa)
VSX2Visual system homeobox 2. (334 aa)
SAMD7Sterile alpha motif domain containing 7. (449 aa)
LOC102175286Long-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (364 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
ARRB2Arrestin beta 2. (420 aa)
LOC102180084Uncharacterized protein; Belongs to the actin family. (319 aa)
PDE6GPhosphodiesterase 6G. (87 aa)
ANKRD33ANK_REP_REGION domain-containing protein. (268 aa)
CNGB1Cyclic nucleotide-binding domain-containing protein. (1344 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
RLBP1Retinaldehyde binding protein 1. (317 aa)
PDE6APhosphodiesterase. (856 aa)
RHORhodopsin. (348 aa)
CALB2Calbindin 2. (271 aa)
LOC108634933Uncharacterized protein. (2452 aa)
ARR3Arrestin 3. (387 aa)
LEUTXHomeobox domain-containing protein. (279 aa)
SHROOM2Shroom family member 2. (1492 aa)
STARD3StAR related lipid transfer domain containing 3. (454 aa)
PDE6BPhosphodiesterase. (893 aa)
SLC45A2Solute carrier family 45 member 2. (535 aa)
CLCN4Chloride channel protein. (760 aa)
SPARCOsteonectin. (303 aa)
CALB1Calbindin 1. (261 aa)
ABCA4ATP binding cassette subfamily A member 4. (2333 aa)
ANKRD33BAnkyrin repeat domain 33B. (488 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
PDZD3PDZ domain containing 3. (471 aa)
EFR3AEFR3 homolog A. (848 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
FAM189A1Family with sequence similarity 189 member A1. (538 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CRXCone-rod homeobox. (299 aa)
CRB3Crumbs cell polarity complex component 3. (128 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1400 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
NCANNeurocan. (1367 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (805 aa)
NYXNyctalopin. (480 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (428 aa)
OLFML2AOlfactomedin like 2A. (648 aa)
CISD2CDGSH iron sulfur domain 2. (135 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1538 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (945 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa)
ACTL8Actin like 8; Belongs to the actin family. (389 aa)
RGRRetinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (291 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (645 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
RP1RP1 axonemal microtubule associated. (2115 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
NRLNeural retina leucine zipper. (262 aa)
RGS16Regulator of G protein signaling 16. (202 aa)
MEGF10Multiple EGF like domains 10. (1135 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
RORBRAR related orphan receptor B. (468 aa)
CERKLCeramide kinase like. (498 aa)
PDE6HPhosphodiesterase 6H. (83 aa)
RPGRIP1RPGR interacting protein 1. (1216 aa)
RCVRNRecoverin. (202 aa)
APPAmyloid beta precursor protein. (770 aa)
TNS4Tensin 4. (694 aa)
ACTG1Actin gamma 1. (376 aa)
RBPMSRNA binding protein, mRNA processing factor. (197 aa)
OLFML2BOlfactomedin like 2B. (759 aa)
GOLGB1Uncharacterized protein. (3258 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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