17 items (Capra hircus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	POLA1	DNA polymerase. (1468 aa)
	ATAD5	ATPase family AAA domain containing 5. (1894 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	RFC1	Replication factor C subunit 1. (1143 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (147 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	POLA2	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (603 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (131 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
	PRIM2	Uncharacterized protein. (219 aa)
	LIG1	DNA ligase. (915 aa)
	PRIM1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (401 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	FEN1	ENSCHIP00000016824	ENSCHIP00000005017	ATPase family AAA domain containing 5.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.891
ATAD5	LIG1	ENSCHIP00000016824	ENSCHIP00000032333	ATPase family AAA domain containing 5.	DNA ligase.	0.766
ATAD5	PCNA	ENSCHIP00000016824	ENSCHIP00000015091	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
ATAD5	POLA1	ENSCHIP00000016824	ENSCHIP00000016749	ATPase family AAA domain containing 5.	DNA polymerase.	0.800
ATAD5	POLA2	ENSCHIP00000016824	ENSCHIP00000024367	ATPase family AAA domain containing 5.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.830
ATAD5	POLE	ENSCHIP00000016824	ENSCHIP00000003433	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.824
ATAD5	POLE2	ENSCHIP00000016824	ENSCHIP00000028310	ATPase family AAA domain containing 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.779
ATAD5	POLE3	ENSCHIP00000016824	ENSCHIP00000022059	ATPase family AAA domain containing 5.	CBFD_NFYB_HMF domain-containing protein.	0.637
ATAD5	POLE4	ENSCHIP00000016824	ENSCHIP00000028280	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.677
ATAD5	PRIM1	ENSCHIP00000016824	ENSCHIP00000033299	ATPase family AAA domain containing 5.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.730
ATAD5	PRIM2	ENSCHIP00000016824	ENSCHIP00000031577	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.776
ATAD5	RFC1	ENSCHIP00000016824	ENSCHIP00000021706	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.728
ATAD5	RFC2	ENSCHIP00000016824	ENSCHIP00000004939	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.969
ATAD5	RFC3	ENSCHIP00000016824	ENSCHIP00000010064	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.975
ATAD5	RFC4	ENSCHIP00000016824	ENSCHIP00000023106	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.988
ATAD5	RFC5	ENSCHIP00000016824	ENSCHIP00000016842	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.969
FEN1	ATAD5	ENSCHIP00000005017	ENSCHIP00000016824	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ATPase family AAA domain containing 5.	0.891
FEN1	LIG1	ENSCHIP00000005017	ENSCHIP00000032333	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.988
FEN1	PCNA	ENSCHIP00000005017	ENSCHIP00000015091	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
FEN1	POLA1	ENSCHIP00000005017	ENSCHIP00000016749	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA polymerase.	0.949