STRINGSTRING
ENSCHIP00000000105 ENSCHIP00000000105 BMPR1A BMPR1A GDF11 GDF11 TGFB3 TGFB3 SKIL SKIL NOG NOG BMP7 BMP7 BMP5 BMP5 GREM1 GREM1 SMAD1 SMAD1 GDF7 GDF7 CHRD CHRD TGFBR2 TGFBR2 SKI SKI TGFB1 TGFB1 GDF5 GDF5 SMAD6 SMAD6 BMP2 BMP2 ACVR1C ACVR1C ACVR2B ACVR2B ACVR2A ACVR2A SMAD3 SMAD3 SMAD5 SMAD5 BAMBI BAMBI TGFBR3 TGFBR3 FST FST SMAD9 SMAD9 INHBC INHBC SMURF1 SMURF1 GDF2 GDF2 ACVR1B ACVR1B SMAD4 SMAD4 SMAD7 SMAD7 SMAD2 SMAD2 BMPR2 BMPR2 BMP4 BMP4 ZFYVE16 ZFYVE16 TGFBR1 TGFBR1 INHBE INHBE ACVR1 ACVR1 TGFB2 TGFB2 MSTN MSTN INHBB INHBB LTBP1 LTBP1 INHBA INHBA BMP10 BMP10 BMP6 BMP6 SMURF2 SMURF2 ACVRL1 ACVRL1 ZFYVE9 ZFYVE9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCHIP00000000105c-SKI_SMAD_bind domain-containing protein. (664 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF11Growth differentiation factor 11. (406 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
SKILc-SKI_SMAD_bind domain-containing protein. (684 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
GREM1Gremlin. (184 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
GDF7Growth differentiation factor 7. (451 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (957 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
SKISKI proto-oncogene. (729 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GDF5Growth differentiation factor 5. (499 aa)
SMAD6Mothers against decapentaplegic homolog. (497 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (522 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
TGFBR3Transforming growth factor beta receptor 3. (859 aa)
FSTUncharacterized protein. (344 aa)
SMAD9Mothers against decapentaplegic homolog. (461 aa)
INHBCInhibin subunit beta C. (352 aa)
SMURF1E3 ubiquitin-protein ligase. (731 aa)
GDF2Growth differentiation factor 2. (430 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1545 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
INHBEInhibin subunit beta E. (348 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
INHBBInhibin subunit beta B. (408 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1491 aa)
INHBAInhibin beta A subunit. (425 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
SMURF2E3 ubiquitin-protein ligase. (741 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1421 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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