STRINGSTRING
CRLF2 CRLF2 CSF2RA CSF2RA IL5 IL5 SOCS1 SOCS1 LOC108633243 LOC108633243 JAK2 JAK2 IL2RG IL2RG CSF3R CSF3R IFNA IFNA JAK3 JAK3 IL2RA IL2RA STAT1 STAT1 IL13RA1 IL13RA1 LOC108636629 LOC108636629 SOCS3 SOCS3 IL5RA IL5RA CSF2RB CSF2RB IL15RA IL15RA JAK1 JAK1 IL10RA IL10RA IL7 IL7 IL13RA2 IL13RA2 IFNGR1 IFNGR1 CSF3 CSF3 IRF9 IRF9 STAT2 STAT2 IFNG IFNG IL2RB IL2RB IL10 IL10 IFNGR2 IFNGR2 LOC102190507 LOC102190507 IFNAR1 IFNAR1 LOC102182821 LOC102182821 TYK2 TYK2 IL4 IL4 IL10RB IL10RB IFNAR2 IFNAR2 IL13 IL13 STAT3 STAT3 IL4R IL4R IL7R IL7R STAT4 STAT4 STAT5B STAT5B STAT5A STAT5A IL21 IL21 IL21R IL21R IFNLR1 IFNLR1 IL15 IL15 IL2 IL2 STAT6 STAT6 SOCS2 SOCS2 CSF2 CSF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRLF2Cytokine receptor like factor 2. (378 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (425 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (129 aa)
SOCS1Suppressor of cytokine signaling 1. (219 aa)
LOC108633243Uncharacterized protein. (186 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL2RGFibronectin type-III domain-containing protein. (378 aa)
CSF3RColony stimulating factor 3 receptor. (840 aa)
IFNAUncharacterized protein. (189 aa)
JAK3Tyrosine-protein kinase. (1138 aa)
IL2RAInterleukin 2 receptor subunit alpha. (285 aa)
STAT1Signal transducer and activator of transcription. (834 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (424 aa)
LOC108636629Uncharacterized protein. (186 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
IL5RAInterleukin 5 receptor subunit alpha. (395 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (890 aa)
IL15RASushi domain-containing protein. (277 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
IL7Interleukin 7. (181 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (380 aa)
IFNGR1Interferon gamma receptor 1. (500 aa)
CSF3Colony stimulating factor 3. (226 aa)
IRF9Interferon regulatory factor 9. (470 aa)
STAT2Signal transducer and activator of transcription. (851 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
IL2RBInterleukin 2 receptor subunit beta. (596 aa)
IL10Interleukin 10. (177 aa)
IFNGR2Interferon gamma receptor 2. (355 aa)
LOC102190507Uncharacterized protein. (139 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (560 aa)
LOC102182821Uncharacterized protein. (207 aa)
TYK2Tyrosine-protein kinase. (1186 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
IL10RBInterleukin 10 receptor subunit beta. (317 aa)
IFNAR2Uncharacterized protein. (534 aa)
IL13Interleukin 13. (131 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
IL4RInterleukin 4 receptor. (805 aa)
IL7RInterleukin 7 receptor. (459 aa)
STAT4Signal transducer and activator of transcription. (797 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (157 aa)
IL21RInterleukin 21 receptor. (531 aa)
IFNLR1Interferon lambda receptor 1. (523 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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