(42 nodes) Proton-transporting V-type ATPase complex, and Pyrophosphate hydrolysis network (Capra hircus)

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Your Input:
	ATP6V1E2	ATPase H+ transporting V1 subunit E2. (226 aa)
	ATP6AP1	ATPase H+ transporting accessory protein 1. (468 aa)
	PPA2	Uncharacterized protein. (342 aa)
	ATP6V1F	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	ATP4B	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	RNASEK	Ribonuclease K. (141 aa)
	ATP6V1G3	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	ENSCHIP00000008002	Uncharacterized protein. (112 aa)
	ATP6V0E2	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	CNST	Consortin, connexin sorting protein. (721 aa)
	ENSCHIP00000009480	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	LIM2	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
	ATP6AP2	Uncharacterized protein. (361 aa)
	ENSCHIP00000011940	Uncharacterized protein. (245 aa)
	ATP6V0A2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
	ATP6V1B1	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
	ATP6V1G1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	PPA1	Pyrophosphatase (inorganic) 1. (289 aa)
	ATP6V1H	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
	ENSCHIP00000016240	Uncharacterized protein. (67 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
	LHPP	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. (270 aa)
	ATP6V1C2	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
	ATP6V0B	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
	ATP6V0D1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	ATP6V1C1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
	ATP4A	Sodium/potassium-transporting ATPase subunit alpha. (1034 aa)
	ATP6V1D	Uncharacterized protein. (237 aa)
	LOC102185906	Uncharacterized protein. (239 aa)
	ATP6V1A	ATPase H+ transporting V1 subunit A. (618 aa)
	ENSCHIP00000022631	Uncharacterized protein. (89 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
	ATP6V0D2	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	ATP6V1E1	ATPase H+ transporting V1 subunit E1. (226 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	ATP12A	Sodium/potassium-transporting ATPase subunit alpha. (1074 aa)
	ATP6V0E1	Uncharacterized protein. (81 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
	ATP6V1G2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
	ENSCHIP00000030469	Uncharacterized protein. (160 aa)
	ATP6AP1L	Uncharacterized protein. (381 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP12A	ATP4A	ENSCHIP00000027379	ENSCHIP00000021447	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.903
ATP12A	ATP4B	ENSCHIP00000027379	ENSCHIP00000005282	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.999
ATP12A	ATP6AP1L	ENSCHIP00000027379	ENSCHIP00000032370	Sodium/potassium-transporting ATPase subunit alpha.	Uncharacterized protein.	0.637
ATP12A	ATP6V0A1	ENSCHIP00000027379	ENSCHIP00000028440	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.427
ATP12A	ATP6V0A2	ENSCHIP00000027379	ENSCHIP00000012401	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.627
ATP12A	ATP6V0A4	ENSCHIP00000027379	ENSCHIP00000029174	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.556
ATP12A	ATP6V0C	ENSCHIP00000027379	ENSCHIP00000026913	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.524
ATP12A	ATP6V0D2	ENSCHIP00000027379	ENSCHIP00000025490	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.555
ATP12A	ATP6V1E2	ENSCHIP00000027379	ENSCHIP00000001438	Sodium/potassium-transporting ATPase subunit alpha.	ATPase H+ transporting V1 subunit E2.	0.448
ATP12A	ATP6V1G3	ENSCHIP00000027379	ENSCHIP00000006434	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.543
ATP12A	LHPP	ENSCHIP00000027379	ENSCHIP00000016791	Sodium/potassium-transporting ATPase subunit alpha.	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.	0.952
ATP12A	PPA1	ENSCHIP00000027379	ENSCHIP00000015694	Sodium/potassium-transporting ATPase subunit alpha.	Pyrophosphatase (inorganic) 1.	0.930
ATP12A	PPA2	ENSCHIP00000027379	ENSCHIP00000004053	Sodium/potassium-transporting ATPase subunit alpha.	Uncharacterized protein.	0.926
ATP12A	TCIRG1	ENSCHIP00000027379	ENSCHIP00000025034	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.429
ATP4A	ATP12A	ENSCHIP00000021447	ENSCHIP00000027379	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.903
ATP4A	ATP4B	ENSCHIP00000021447	ENSCHIP00000005282	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.999
ATP4A	ATP6V0A1	ENSCHIP00000021447	ENSCHIP00000028440	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.517
ATP4A	ATP6V0A2	ENSCHIP00000021447	ENSCHIP00000012401	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.599
ATP4A	ATP6V0A4	ENSCHIP00000021447	ENSCHIP00000029174	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.434
ATP4A	ATP6V0C	ENSCHIP00000021447	ENSCHIP00000026913	Sodium/potassium-transporting ATPase subunit alpha.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.442