STRINGSTRING
STAG2 STAG2 KLHL22 KLHL22 TUBGCP3 TUBGCP3 PLK3 PLK3 FAM110A FAM110A POC1A POC1A ENSCHIP00000001650 ENSCHIP00000001650 TBCCD1 TBCCD1 VPS4B VPS4B MAP10 MAP10 CETN1 CETN1 ENSCHIP00000003493 ENSCHIP00000003493 NUMA1 NUMA1 CUL3 CUL3 TNKS TNKS CEP85 CEP85 SMC1A SMC1A NUP62CL NUP62CL BIRC6 BIRC6 IK IK ODF2 ODF2 CDC6 CDC6 NEK2 NEK2 HSF1 HSF1 CDC14C CDC14C CALML5 CALML5 SPOUT1 SPOUT1 BEX4 BEX4 LOC102168398 LOC102168398 SMC6 SMC6 ASPM ASPM LOC102187271 LOC102187271 MAPKBP1 MAPKBP1 RAD21 RAD21 KNTC1 KNTC1 CALM2 CALM2 CALM3 CALM3 SMC3 SMC3 KATNAL1 KATNAL1 VPS4A VPS4A CKAP2L CKAP2L TPT1 TPT1 BCCIP-2 BCCIP-2 LOC102189098 LOC102189098 NUP62 NUP62 RAB11A RAB11A CENPF CENPF TOPORS TOPORS KIF2A KIF2A ENSCHIP00000011450 ENSCHIP00000011450 SGO1 SGO1 DYNC1I1 DYNC1I1 CDK5RAP2 CDK5RAP2 RSKR RSKR CEP89 CEP89 UNC119 UNC119 EFHC1 EFHC1 TPT1-2 TPT1-2 TUBGCP2 TUBGCP2 CDC14A CDC14A AUNIP AUNIP SPDL1 SPDL1 UMOD UMOD SPAST SPAST KAT5 KAT5 CDC25B CDC25B TUBGCP4 TUBGCP4 CEP95 CEP95 UBXN2B UBXN2B CTDP1 CTDP1 BCCIP BCCIP EML1 EML1 BOD1L1 BOD1L1 DLGAP5 DLGAP5 KATNA1 KATNA1 KIF11 KIF11 WDR60 WDR60 BRCC3 BRCC3 PKP4 PKP4 CKAP5 CKAP5 AURKC AURKC ENSCHIP00000020042 ENSCHIP00000020042 ENSCHIP00000020312 ENSCHIP00000020312 AAAS AAAS YPEL YPEL ALPK1 ALPK1 WDR62 WDR62 LOC108634984 LOC108634984 LATS2 LATS2 ENSCHIP00000023367 ENSCHIP00000023367 PSRC1 PSRC1 NEDD9 NEDD9 KATNAL2 KATNAL2 TUBGCP6 TUBGCP6 WDR73 WDR73 RAE1 RAE1 CALM1 CALM1 BOD1 BOD1 MISP MISP UXT UXT ABRAXAS2 ABRAXAS2 ENSCHIP00000024778 ENSCHIP00000024778 GIT1 GIT1 RMDN1 RMDN1 MAD1L1 MAD1L1 RMDN2 RMDN2 GPSM2 GPSM2 EMD EMD PLK1 PLK1 AURKB AURKB ENSCHIP00000026753 ENSCHIP00000026753 MTCL1 MTCL1 MAPRE1 MAPRE1 FBF1 FBF1 PLK4 PLK4 FAM83D FAM83D CSPP1 CSPP1 IKBKG IKBKG CEP19 CEP19 ENSCHIP00000027893 ENSCHIP00000027893 TUBG1 TUBG1 PPP2CA PPP2CA NDE1 NDE1 PLK5 PLK5 TPX2 TPX2 SPAG5 SPAG5 NUBP2 NUBP2 EFCAB3 EFCAB3 KATNA1-2 KATNA1-2 AURKA AURKA RMDN3 RMDN3 NIN NIN DYNC1LI1 DYNC1LI1 DCTN1 DCTN1 ENSCHIP00000029741 ENSCHIP00000029741 NEDD1 NEDD1 YPEL5 YPEL5 TUBGCP5 TUBGCP5 CTNNB1 CTNNB1 PLK2 PLK2 ENSCHIP00000031586 ENSCHIP00000031586 ZW10 ZW10 ENSCHIP00000031750 ENSCHIP00000031750 CEP44 CEP44 TMEM201 TMEM201 POC1B POC1B CEP128 CEP128 KLHL21 KLHL21 KATNB1 KATNB1 SBDS SBDS CCDC155 CCDC155 LATS1 LATS1 HAUS1 HAUS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAG2Stromal antigen 2. (1268 aa)
KLHL22Kelch like family member 22. (634 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (907 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
FAM110AFamily with sequence similarity 110 member A. (295 aa)
POC1APOC1 centriolar protein A. (407 aa)
ENSCHIP00000001650TCTP domain-containing protein; Belongs to the TCTP family. (154 aa)
TBCCD1TBCC domain containing 1. (557 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
MAP10Microtubule associated protein 10. (909 aa)
CETN1Centrin 1. (172 aa)
ENSCHIP00000003493MPN domain-containing protein. (262 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2115 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
CEP85Centrosomal protein 85. (728 aa)
SMC1AStructural maintenance of chromosomes protein. (1188 aa)
NUP62CLNsp1_C domain-containing protein. (304 aa)
BIRC6Baculoviral IAP repeat containing 6. (4878 aa)
IKIK cytokine. (530 aa)
ODF2Outer dense fiber of sperm tails 2. (829 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (562 aa)
NEK2NIMA related kinase 2. (445 aa)
HSF1HSF_DOMAIN domain-containing protein. (537 aa)
CDC14CCell division cycle 14C. (485 aa)
CALML5Calmodulin like 5. (149 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (359 aa)
BEX4Brain expressed X-linked 4. (120 aa)
LOC102168398TCTP domain-containing protein; Belongs to the TCTP family. (172 aa)
SMC6Structural maintenance of chromosomes 6. (1116 aa)
ASPMAbnormal spindle microtubule assembly. (3460 aa)
LOC102187271Rhodanese domain-containing protein. (506 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1497 aa)
RAD21RAD21 cohesin complex component. (630 aa)
KNTC1Kinetochore associated 1. (2134 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (150 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (159 aa)
SMC3Structural maintenance of chromosomes protein. (1231 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (442 aa)
CKAP2LCytoskeleton associated protein 2 like. (769 aa)
TPT1TCTP domain-containing protein; Belongs to the TCTP family. (172 aa)
BCCIP-2BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (305 aa)
LOC102189098MPN domain-containing protein. (291 aa)
NUP62Nucleoporin 62. (523 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
CENPFCentromere protein F. (3055 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1034 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
ENSCHIP00000011450Uncharacterized protein. (110 aa)
SGO1Shugoshin 1. (577 aa)
DYNC1I1WD_REPEATS_REGION domain-containing protein. (524 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1870 aa)
RSKRRibosomal protein S6 kinase related. (404 aa)
CEP89Centrosomal protein 89. (770 aa)
UNC119Unc-119 lipid binding chaperone. (248 aa)
EFHC1EF-hand domain containing 1. (640 aa)
TPT1-2TCTP domain-containing protein; Belongs to the TCTP family. (192 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (905 aa)
CDC14ACell division cycle 14A. (627 aa)
AUNIPAurora kinase A and ninein interacting protein. (357 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (603 aa)
UMODUromodulin. (643 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (614 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CDC25BRhodanese domain-containing protein. (564 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (666 aa)
CEP95Centrosomal protein 95. (820 aa)
UBXN2BUBX domain protein 2B. (318 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (931 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (298 aa)
EML1EMAP like 1. (835 aa)
BOD1L1Uncharacterized protein. (2004 aa)
DLGAP5DLG associated protein 5. (843 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1055 aa)
WDR60Uncharacterized protein. (1068 aa)
BRCC3MPN domain-containing protein. (288 aa)
PKP4Plakophilin 4. (1193 aa)
CKAP5Cytoskeleton associated protein 5. (2040 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (336 aa)
ENSCHIP00000020042MPN domain-containing protein. (245 aa)
ENSCHIP00000020312TCTP domain-containing protein; Belongs to the TCTP family. (123 aa)
AAASAladin WD repeat nucleoporin. (547 aa)
YPELProtein yippee-like; Belongs to the yippee family. (118 aa)
ALPK1Alpha kinase 1. (1241 aa)
WDR62WD repeat domain 62. (1516 aa)
LOC108634984Uncharacterized protein. (140 aa)
LATS2Large tumor suppressor kinase 2. (1015 aa)
ENSCHIP00000023367Calponin-homology (CH) domain-containing protein. (228 aa)
PSRC1Proline and serine rich coiled-coil 1. (326 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (826 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
TUBGCP6Tubulin gamma complex associated protein 6. (1584 aa)
WDR73WD repeat domain 73. (370 aa)
RAE1Ribonucleic acid export 1. (368 aa)
CALM1Calmodulin 2; Belongs to the calmodulin family. (149 aa)
BOD1Uncharacterized protein. (185 aa)
MISPMitotic spindle positioning. (689 aa)
UXTUbiquitously expressed prefoldin like chaperone. (156 aa)
ABRAXAS2MPN domain-containing protein. (404 aa)
ENSCHIP00000024778Uncharacterized protein; Belongs to the calmodulin family. (134 aa)
GIT1GIT ArfGAP 1. (738 aa)
RMDN1Regulator of microtubule dynamics 1. (317 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (725 aa)
RMDN2Uncharacterized protein. (410 aa)
GPSM2G protein signaling modulator 2. (689 aa)
EMDEmerin. (261 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
ENSCHIP00000026753Uncharacterized protein. (107 aa)
MTCL1Microtubule crosslinking factor 1. (1913 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
FBF1Fas binding factor 1. (1033 aa)
PLK4Polo like kinase 4. (933 aa)
FAM83DFamily with sequence similarity 83 member D. (582 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1193 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa)
CEP19Centrosomal protein 19. (163 aa)
ENSCHIP00000027893Uncharacterized protein. (123 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
PLK5Protein kinase domain-containing protein. (562 aa)
TPX2TPX2 microtubule nucleation factor. (746 aa)
SPAG5Sperm associated antigen 5. (1198 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (273 aa)
EFCAB3EF-hand calcium binding domain 3. (438 aa)
KATNA1-2Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (479 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
RMDN3Regulator of microtubule dynamics 3. (471 aa)
NINNinein. (2137 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
DCTN1CAP-Gly domain-containing protein. (1262 aa)
ENSCHIP00000029741Uncharacterized protein. (105 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (659 aa)
YPEL5Yippee domain-containing protein. (287 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa)
CTNNB1Catenin beta 1. (781 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
ENSCHIP00000031586Uncharacterized protein. (337 aa)
ZW10Zw10 kinetochore protein. (779 aa)
ENSCHIP00000031750SMC_N domain-containing protein. (189 aa)
CEP44Centrosomal protein 44. (414 aa)
TMEM201Transmembrane protein 201. (672 aa)
POC1BPOC1 centriolar protein B. (478 aa)
CEP128Centrosomal protein 128. (1232 aa)
KLHL21Kelch like family member 21. (597 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (663 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
CCDC155Coiled-coil domain containing 155. (505 aa)
LATS1Large tumor suppressor kinase 1. (1145 aa)
HAUS1HAUS augmin like complex subunit 1. (278 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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