43 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TYK2	Tyrosine-protein kinase. (1186 aa)
	ITK	Tyrosine-protein kinase. (619 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	MELK	Non-specific serine/threonine protein kinase. (650 aa)
	DYRK1A	Dual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
	PTK6	Tyrosine-protein kinase. (450 aa)
	AMOT	Angiomotin. (854 aa)
	BLK	Tyrosine-protein kinase. (501 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	TEC	Tyrosine-protein kinase. (632 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	HCK	Tyrosine-protein kinase. (528 aa)
	ABL1	Tyrosine-protein kinase. (1151 aa)
	PEAK1	Pseudopodium enriched atypical kinase 1. (1747 aa)
	BTK	Tyrosine-protein kinase. (658 aa)
	BMX	Tyrosine-protein kinase. (655 aa)
	WEE2	Wee1-like protein kinase. (566 aa)
	NDRG3	NDRG family member 3. (375 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
	WEE1	Wee1-like protein kinase. (645 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (804 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
	FGR	Tyrosine-protein kinase. (527 aa)
	MATK	Tyrosine-protein kinase. (485 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa)
	SRMS	Tyrosine-protein kinase. (494 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	TXK	Tyrosine-protein kinase. (527 aa)
	JAK1	Tyrosine-protein kinase. (1159 aa)
	ABL2	Tyrosine-protein kinase. (1182 aa)
	TNK2	Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
	ZAP70	Tyrosine-protein kinase. (622 aa)
	SYK	Spleen associated tyrosine kinase. (636 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (493 aa)
	JAK3	Tyrosine-protein kinase. (1138 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	TNK1	Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (644 aa)
	FRK	Tyrosine-protein kinase. (515 aa)
	SRC	Tyrosine-protein kinase. (538 aa)
	STYK1	Serine/threonine/tyrosine kinase 1. (426 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	LOC102176379	Wee1-like protein kinase. (549 aa)
	YES1	Tyrosine-protein kinase. (541 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSCHIP00000024651	ENSCHIP00000009993	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.941
ABL1	FGR	ENSCHIP00000024651	ENSCHIP00000014330	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.483
ABL1	JAK2	ENSCHIP00000024651	ENSCHIP00000001875	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.559
ABL1	SYK	ENSCHIP00000024651	ENSCHIP00000009361	Tyrosine-protein kinase.	Spleen associated tyrosine kinase.	0.485
ABL1	ZAP70	ENSCHIP00000024651	ENSCHIP00000009493	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.417
ABL2	ABL1	ENSCHIP00000009993	ENSCHIP00000024651	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.941
BLK	CSK	ENSCHIP00000027296	ENSCHIP00000026709	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.627
BLK	MATK	ENSCHIP00000027296	ENSCHIP00000013015	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.632
BLK	PTK2	ENSCHIP00000027296	ENSCHIP00000012150	Tyrosine-protein kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.544
BLK	PTK2B	ENSCHIP00000027296	ENSCHIP00000032215	Tyrosine-protein kinase.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.544
BLK	SYK	ENSCHIP00000027296	ENSCHIP00000009361	Tyrosine-protein kinase.	Spleen associated tyrosine kinase.	0.551
BLK	ZAP70	ENSCHIP00000027296	ENSCHIP00000009493	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.496
BMX	HCK	ENSCHIP00000023320	ENSCHIP00000024781	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.402
BMX	LCK	ENSCHIP00000023320	ENSCHIP00000011857	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.408
BMX	LYN	ENSCHIP00000023320	ENSCHIP00000025862	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.610
BMX	PTK2	ENSCHIP00000023320	ENSCHIP00000012150	Tyrosine-protein kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.460
BMX	SYK	ENSCHIP00000023320	ENSCHIP00000009361	Tyrosine-protein kinase.	Spleen associated tyrosine kinase.	0.634
BMX	ZAP70	ENSCHIP00000023320	ENSCHIP00000009493	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.483
BTK	FGR	ENSCHIP00000023722	ENSCHIP00000014330	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.428
BTK	FYN	ENSCHIP00000023722	ENSCHIP00000004966	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.566