STRINGSTRING
LUC7L3 LUC7L3 PPIE PPIE SNRPG SNRPG RBM8A RBM8A LOC102172949 LOC102172949 PRPF40A PRPF40A EFTUD2 EFTUD2 XAB2 XAB2 BUD13 BUD13 SRRM2 SRRM2 SF3B2 SF3B2 LSM4 LSM4 ENSCHIP00000006634 ENSCHIP00000006634 PRPF39 PRPF39 SNW1 SNW1 SF3B6 SF3B6 LOC102172789 LOC102172789 SNRNP40 SNRNP40 DHX8 DHX8 SNRPB2 SNRPB2 ENSCHIP00000004875 ENSCHIP00000004875 IK IK LOC102174442 LOC102174442 SF3B5 SF3B5 CASC3 CASC3 SNRPD1 SNRPD1 SNRPC SNRPC ENSCHIP00000002186 ENSCHIP00000002186 ENSCHIP00000001288 ENSCHIP00000001288 PRPF18 PRPF18 HTATSF1 HTATSF1 SNRPD3 SNRPD3 MAGOHB MAGOHB SMU1 SMU1 ENSCHIP00000033192 ENSCHIP00000033192 DHX15 DHX15 SNRPB SNRPB AQR AQR PRPF38A PRPF38A PRPF4 PRPF4 LSM3 LSM3 ENSCHIP00000029494 ENSCHIP00000029494 EIF4A3 EIF4A3 PRPF40B PRPF40B ENSCHIP00000028361 ENSCHIP00000028361 LSM7 LSM7 U2AF2 U2AF2 ENSCHIP00000026270 ENSCHIP00000026270 BCAS2 BCAS2 CDC5L CDC5L PRPF31 PRPF31 SYF2 SYF2 SNRNP200 SNRNP200 SF3A3 SF3A3 SF3B3 SF3B3 TXNL4A TXNL4A RNF113A RNF113A SF3A1 SF3A1 SNRNP70 SNRNP70 PRPF19 PRPF19 SF3A2 SF3A2 PRPF6 PRPF6 CDC40 CDC40 PRPF8 PRPF8 SNRPN SNRPN LUC7L LUC7L CWC22 CWC22 TFIP11 TFIP11 SNRPF SNRPF YJU2 YJU2 LOC102173595 LOC102173595 SNRPD2-2 SNRPD2-2 SART1 SART1 SNRPA1 SNRPA1 CWC27 CWC27 LSM2 LSM2 ENSCHIP00000015364 ENSCHIP00000015364 GCFC2 GCFC2 SNU13 SNU13 PHF5A PHF5A SNRPD2 SNRPD2 LOC102186560 LOC102186560 RBM22 RBM22 PRPF3 PRPF3 BUD31 BUD31 SF3B1 SF3B1 CWC25 CWC25 ZMAT2 ZMAT2 ENSCHIP00000013274 ENSCHIP00000013274 CCDC12 CCDC12 ENSCHIP00000012479 ENSCHIP00000012479 LSM8 LSM8 PLRG1 PLRG1 MFAP1 MFAP1 CCDC130 CCDC130 SNIP1 SNIP1 DHX16 DHX16 CRNKL1 CRNKL1 WBP4 WBP4 LOC102174705 LOC102174705 ENSCHIP00000009900 ENSCHIP00000009900
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (491 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (292 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
LOC102172949U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (890 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
XAB2XPA binding protein 2. (892 aa)
BUD13BUD13 homolog. (653 aa)
SRRM2Serine/arginine repetitive matrix 2. (2680 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa)
ENSCHIP00000006634Uncharacterized protein. (132 aa)
PRPF39Pre-mRNA processing factor 39. (667 aa)
SNW1SNW domain containing 1. (536 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
LOC102172789Uncharacterized protein. (376 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (358 aa)
DHX8DEAH-box helicase 8. (1216 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
ENSCHIP00000004875Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
IKIK cytokine. (530 aa)
LOC102174442Uncharacterized protein. (284 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
CASC3CASC3 exon junction complex subunit. (700 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa)
ENSCHIP00000002186Uncharacterized protein. (123 aa)
ENSCHIP00000001288Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
PRPF18SFM domain-containing protein. (351 aa)
HTATSF1HIV-1 Tat specific factor 1. (774 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
MAGOHBUncharacterized protein. (148 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
ENSCHIP00000033192WD_REPEATS_REGION domain-containing protein. (219 aa)
DHX15DEAH-box helicase 15. (795 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1471 aa)
PRPF38APre-mRNA processing factor 38A. (312 aa)
PRPF4WD_REPEATS_REGION domain-containing protein. (522 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
ENSCHIP00000029494Sm domain-containing protein. (73 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (865 aa)
ENSCHIP00000028361Uncharacterized protein. (251 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (426 aa)
ENSCHIP00000026270Sm domain-containing protein. (62 aa)
BCAS2Uncharacterized protein. (225 aa)
CDC5LCell division cycle 5 like. (802 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2146 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
RNF113AUncharacterized protein. (343 aa)
SF3A1Splicing factor 3a subunit 1. (808 aa)
SNRNP70RRM domain-containing protein. (166 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
SF3A2Splicing factor 3a subunit 2. (477 aa)
PRPF6Pre-mRNA processing factor 6. (948 aa)
CDC40Cell division cycle 40. (592 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (240 aa)
LUC7LLUC7 like. (369 aa)
CWC22CWC22 spliceosome associated protein homolog. (900 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
SNRPFSm domain-containing protein. (68 aa)
YJU2Uncharacterized protein. (320 aa)
LOC102173595Uncharacterized protein. (314 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (96 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (796 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
CWC27CWC27 spliceosome associated cyclophilin. (473 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa)
ENSCHIP00000015364Ribosomal_L7Ae domain-containing protein. (112 aa)
GCFC2GC-rich sequence DNA-binding factor 2. (782 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (129 aa)
PHF5APHD finger protein 5A. (107 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (119 aa)
LOC102186560Uncharacterized protein. (340 aa)
RBM22RNA binding motif protein 22. (420 aa)
PRPF3Pre-mRNA processing factor 3. (683 aa)
BUD31BUD31 homolog. (144 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
CWC25CWC25 spliceosome associated protein homolog. (425 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
ENSCHIP00000013274Sm domain-containing protein. (87 aa)
CCDC12Coiled-coil domain containing 12. (168 aa)
ENSCHIP00000012479Uncharacterized protein. (215 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
MFAP1Microfibril associated protein 1. (439 aa)
CCDC130Coiled-coil domain containing 130. (399 aa)
SNIP1Smad nuclear interacting protein 1. (429 aa)
DHX16DEAH-box helicase 16. (1058 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (693 aa)
WBP4WW domain binding protein 4. (377 aa)
LOC102174705Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
ENSCHIP00000009900Uncharacterized protein. (130 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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