STRINGSTRING
ENSCHIP00000001595 ENSCHIP00000001595 TIMELESS TIMELESS ACTR5 ACTR5 SMC3 SMC3 TERF1 TERF1 AICDA AICDA CDT1 CDT1 RFC3 RFC3 ZNF830 ZNF830 ENSCHIP00000010204 ENSCHIP00000010204 ESCO2 ESCO2 EHMT2 EHMT2 ENSCHIP00000011218 ENSCHIP00000011218 OBI1 OBI1 YY1 YY1 ATRX ATRX WAPL WAPL RBBP6 RBBP6 SMARCA5 SMARCA5 SSBP1 SSBP1 ENSCHIP00000012571 ENSCHIP00000012571 ZMPSTE24 ZMPSTE24 DSCC1 DSCC1 NRM NRM WRNIP1 WRNIP1 TSPYL2 TSPYL2 INO80D INO80D BLM BLM INO80 INO80 ZBTB38 ZBTB38 LOC102170015 LOC102170015 RFC2 RFC2 CHTF18 CHTF18 TICRR TICRR INO80C INO80C METTL4 METTL4 TIPIN TIPIN EREG EREG BCAR3 BCAR3 ENSCHIP00000001457 ENSCHIP00000001457 MEAF6 MEAF6 DACH1 DACH1 UCHL5 UCHL5 LOC106502849 LOC106502849 CDK2 CDK2 GLI1 GLI1 CIZ1 CIZ1 USP37 USP37 GMNN GMNN STN1 STN1 BAZ1A BAZ1A LOC108638223 LOC108638223 RUVBL1 RUVBL1 MCRS1 MCRS1 DNA2 DNA2 ACTL6A ACTL6A ATAD5 ATAD5 ORC5 ORC5 NUGGC NUGGC JADE1 JADE1 ACTR8 ACTR8 PCNA PCNA NUCKS1 NUCKS1 ENSCHIP00000015450 ENSCHIP00000015450 ESCO1 ESCO1 LOC108637664 LOC108637664 GINS2 GINS2 GINS4 GINS4 DHX9 DHX9 ENSCHIP00000019664 ENSCHIP00000019664 JADE3 JADE3 ANKRD17 ANKRD17 CCNA2 CCNA2 INO80E INO80E POLG2 POLG2 CHRAC1 CHRAC1 POLE3 POLE3 MCIDAS MCIDAS DONSON DONSON EGFR EGFR DBF4 DBF4 BRPF3 BRPF3 ENDOG ENDOG RAD17 RAD17 RFC4 RFC4 NFRKB NFRKB GINS3 GINS3 BRCA2 BRCA2 WBP1 WBP1 ATR ATR ENPP7 ENPP7 GMNC GMNC E2F8 E2F8 E2F7 E2F7 CDAN1 CDAN1 LIG3 LIG3 INO80B INO80B ORC3 ORC3 RUVBL2 RUVBL2 CTC1 CTC1 TFPT TFPT TP53 TP53 DERPC DERPC SMARCAL1 SMARCAL1 ZRANB3 ZRANB3 STOML2 STOML2 KAT7 KAT7 NPM2 NPM2 PDS5A PDS5A UCN UCN FBXO5 FBXO5 CDC7 CDC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCHIP00000001595Uncharacterized protein. (333 aa)
TIMELESSTimeless circadian regulator. (1206 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (615 aa)
SMC3Structural maintenance of chromosomes protein. (1231 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
CDT1Chromatin licensing and DNA replication factor 1. (637 aa)
RFC3Replication factor C subunit 3. (356 aa)
ZNF830Zinc finger protein 830. (361 aa)
ENSCHIP00000010204TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (275 aa)
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (610 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
ENSCHIP00000011218Uncharacterized protein. (167 aa)
OBI1ORC ubiquitin ligase 1. (718 aa)
YY1YY1 transcription factor. (415 aa)
ATRXATRX chromatin remodeler. (2105 aa)
WAPLWAPL cohesin release factor. (1193 aa)
RBBP6RB binding protein 6, ubiquitin ligase. (1797 aa)
SMARCA5Uncharacterized protein. (1052 aa)
SSBP1Uncharacterized protein. (148 aa)
ENSCHIP00000012571Uncharacterized protein. (386 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
DSCC1Uncharacterized protein. (388 aa)
NRMNurim. (262 aa)
WRNIP1WRN helicase interacting protein 1. (640 aa)
TSPYL2TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (699 aa)
INO80DINO80 complex subunit D. (1026 aa)
BLMBLM RecQ like helicase. (1429 aa)
INO80INO80 complex ATPase subunit. (1566 aa)
ZBTB38Zinc finger and BTB domain containing 38. (1203 aa)
LOC102170015Uncharacterized protein. (384 aa)
RFC2Replication factor C subunit 2. (352 aa)
CHTF18Chromosome transmission fidelity factor 18. (948 aa)
TICRRTOPBP1 interacting checkpoint and replication regulator. (1900 aa)
INO80CINO80 complex subunit C. (192 aa)
METTL4Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa)
EREGEpiregulin. (163 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (826 aa)
ENSCHIP00000001457PAPA-1 domain-containing protein. (349 aa)
MEAF6MYST/Esa1 associated factor 6. (201 aa)
DACH1Dachshund family transcription factor 1. (761 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (325 aa)
LOC106502849Uncharacterized protein. (242 aa)
CDK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
GLI1GLI family zinc finger 1. (1105 aa)
CIZ1CDKN1A interacting zinc finger protein 1. (842 aa)
USP37Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
GMNNGeminin DNA replication inhibitor. (186 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa)
BAZ1ABromodomain adjacent to zinc finger domain 1A. (1558 aa)
LOC108638223Uncharacterized protein. (145 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MCRS1Microspherule protein 1. (462 aa)
DNA2DNA replication helicase/nuclease 2. (1062 aa)
ACTL6AActin like 6A; Belongs to the actin family. (458 aa)
ATAD5ATPase family AAA domain containing 5. (1894 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
NUGGCNuclear GTPase, germinal center associated. (794 aa)
JADE1Jade family PHD finger 1. (863 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
NUCKS1Uncharacterized protein. (248 aa)
ENSCHIP00000015450BRCT domain-containing protein. (152 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (841 aa)
LOC108637664Uncharacterized protein. (1041 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
DHX9DExH-box helicase 9. (1271 aa)
ENSCHIP00000019664CBFD_NFYB_HMF domain-containing protein. (126 aa)
JADE3Jade family PHD finger 3. (859 aa)
ANKRD17Ankyrin repeat domain 17. (2604 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (430 aa)
INO80EINO80 complex subunit E. (241 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (485 aa)
CHRAC1CBFD_NFYB_HMF domain-containing protein. (130 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (147 aa)
MCIDASMulticiliate differentiation and DNA synthesis associated cell cycle protein. (374 aa)
DONSONDownstream neighbor of SON. (561 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
DBF4DBF4 zinc finger. (675 aa)
BRPF3Bromodomain and PHD finger containing 3. (1208 aa)
ENDOGEndonuclease. (299 aa)
RAD17RAD17 checkpoint clamp loader component. (709 aa)
RFC4Replication factor C subunit 4. (364 aa)
NFRKBNuclear factor related to kappaB binding protein. (1298 aa)
GINS3GINS complex subunit 3. (216 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
WBP1WW domain binding protein 1. (303 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (435 aa)
GMNCGeminin coiled-coil domain containing. (336 aa)
E2F8E2F transcription factor 8. (866 aa)
E2F7E2F transcription factor 7. (911 aa)
CDAN1Codanin 1. (1230 aa)
LIG3DNA ligase. (1004 aa)
INO80BPAPA-1 domain-containing protein. (373 aa)
ORC3Origin recognition complex subunit 3. (712 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (471 aa)
CTC1CST telomere replication complex component 1. (1210 aa)
TFPTTCF3 fusion partner. (254 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
DERPCDERPC proline and glycine rich nuclear protein. (520 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1070 aa)
STOML2Stomatin like 2. (356 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
NPM2Nucleophosmin/nucleoplasmin 2. (197 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
UCNUrocortin. (124 aa)
FBXO5F-box protein 5. (448 aa)
CDC7Cell division cycle 7. (576 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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