21 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EXO1	Exonuclease 1. (835 aa)
	MLH1	MutL homolog 1. (758 aa)
	MSH3	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa)
	MSH2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	MUTYH	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (605 aa)
	MLH3	MutL homolog 3. (1463 aa)
	ENSCHIP00000002654	Uncharacterized protein. (121 aa)
	RPA3	Uncharacterized protein. (121 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	MSH4	MutS homolog 4. (930 aa)
	MSH5	DNA_MISMATCH_REPAIR_2 domain-containing protein. (821 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2556 aa)
	MCM9	Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1137 aa)
	XPC	XPC complex subunit, DNA damage recognition and repair factor. (877 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (887 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	TDG	Thymine DNA glycosylase. (403 aa)
	RNASEH2A	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (301 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
	PMS1	PMS1 homolog 1, mismatch repair system component. (932 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCHIP00000002654	ERCC1	ENSCHIP00000002654	ENSCHIP00000031141	Uncharacterized protein.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.479
ENSCHIP00000002654	EXO1	ENSCHIP00000002654	ENSCHIP00000010493	Uncharacterized protein.	Exonuclease 1.	0.519
ENSCHIP00000002654	MCM9	ENSCHIP00000002654	ENSCHIP00000019444	Uncharacterized protein.	Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.	0.539
ENSCHIP00000002654	MLH1	ENSCHIP00000002654	ENSCHIP00000008937	Uncharacterized protein.	MutL homolog 1.	0.496
ENSCHIP00000002654	MSH2	ENSCHIP00000002654	ENSCHIP00000025009	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.476
ENSCHIP00000002654	MSH6	ENSCHIP00000002654	ENSCHIP00000012330	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.470
ENSCHIP00000002654	PCNA	ENSCHIP00000002654	ENSCHIP00000015091	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.622
ENSCHIP00000002654	PMS1	ENSCHIP00000002654	ENSCHIP00000011013	Uncharacterized protein.	PMS1 homolog 1, mismatch repair system component.	0.435
ENSCHIP00000002654	PMS2	ENSCHIP00000002654	ENSCHIP00000017031	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.455
ENSCHIP00000002654	RPA1	ENSCHIP00000002654	ENSCHIP00000032279	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.975
ENSCHIP00000002654	XPC	ENSCHIP00000002654	ENSCHIP00000018162	Uncharacterized protein.	XPC complex subunit, DNA damage recognition and repair factor.	0.435
ERCC1	ENSCHIP00000002654	ENSCHIP00000031141	ENSCHIP00000002654	ERCC excision repair 1, endonuclease non-catalytic subunit.	Uncharacterized protein.	0.479
ERCC1	EXO1	ENSCHIP00000031141	ENSCHIP00000010493	ERCC excision repair 1, endonuclease non-catalytic subunit.	Exonuclease 1.	0.811
ERCC1	MLH1	ENSCHIP00000031141	ENSCHIP00000008937	ERCC excision repair 1, endonuclease non-catalytic subunit.	MutL homolog 1.	0.663
ERCC1	MLH3	ENSCHIP00000031141	ENSCHIP00000005791	ERCC excision repair 1, endonuclease non-catalytic subunit.	MutL homolog 3.	0.541
ERCC1	MSH2	ENSCHIP00000031141	ENSCHIP00000025009	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.896
ERCC1	MSH3	ENSCHIP00000031141	ENSCHIP00000032746	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.843
ERCC1	MSH4	ENSCHIP00000031141	ENSCHIP00000032331	ERCC excision repair 1, endonuclease non-catalytic subunit.	MutS homolog 4.	0.572
ERCC1	MSH6	ENSCHIP00000031141	ENSCHIP00000012330	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.818
ERCC1	PMS1	ENSCHIP00000031141	ENSCHIP00000011013	ERCC excision repair 1, endonuclease non-catalytic subunit.	PMS1 homolog 1, mismatch repair system component.	0.602