STRINGSTRING
SMC5 SMC5 RAD51D RAD51D XRCC1 XRCC1 XRCC3 XRCC3 BRCA2 BRCA2 MSH2 MSH2 RAD50 RAD50 ENSCHIP00000003676 ENSCHIP00000003676 RAD52 RAD52 SMC6 SMC6 GEN1 GEN1 RAD51 RAD51 NSMCE2 NSMCE2 MSH3 MSH3 TEP1 TEP1 TPRKB TPRKB ERCC4 ERCC4 DMC1 DMC1 ERCC1 ERCC1 RAD51C RAD51C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMC5AAA_23 domain-containing protein. (1104 aa)
RAD51DDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (338 aa)
XRCC1X-ray repair cross complementing 1. (632 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (341 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
RAD50Zinc-hook domain-containing protein. (1332 aa)
ENSCHIP00000003676RECA_2 domain-containing protein. (278 aa)
RAD52RAD52 homolog, DNA repair protein. (416 aa)
SMC6Structural maintenance of chromosomes 6. (1116 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (931 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (277 aa)
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa)
TEP1Telomerase associated protein 1. (2633 aa)
TPRKBTP53RK binding protein; Belongs to the CGI121/TPRKB family. (175 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
RAD51CRAD51 paralog C. (371 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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