26 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	GLS2	Glutaminase 2. (605 aa)
	GLUD1	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (561 aa)
	SIRT4	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa)
	ENSCHIP00000033303	Uncharacterized protein. (177 aa)
	CTPS1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
	ENSCHIP00000032125	Asparagine synthetase domain-containing protein. (158 aa)
	GFPT2	Glutamine-fructose-6-phosphate transaminase 2. (676 aa)
	GLUL	Glutamine synthetase. (373 aa)
	NIT2	Nitrilase family member 2. (283 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	ASNSD1	Glutamine amidotransferase type-2 domain-containing protein. (638 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (481 aa)
	GMPS	Guanine monophosphate synthase. (693 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2242 aa)
	GFPT1	Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
	ENSCHIP00000020653	Glutamine amidotransferase type-2 domain-containing protein. (361 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	ENSCHIP00000015922	Asparagine synthetase domain-containing protein. (156 aa)
	ASL	Uncharacterized protein. (473 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	ENSCHIP00000011073	Uncharacterized protein. (200 aa)
	PFAS	Phosphoribosylformylglycinamidine synthase. (1372 aa)
	ENSCHIP00000005654	Uncharacterized protein. (132 aa)
	GLS	Glutaminase. (673 aa)
	ENSCHIP00000004162	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (515 aa)
	CTPS2	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASL	CAD	ENSCHIP00000014908	ENSCHIP00000025740	Uncharacterized protein.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.775
ASL	CPS1	ENSCHIP00000014908	ENSCHIP00000030166	Uncharacterized protein.	Carbamoyl-phosphate synthase 1.	0.919
ASL	GLS	ENSCHIP00000014908	ENSCHIP00000004326	Uncharacterized protein.	Glutaminase.	0.630
ASL	GLS2	ENSCHIP00000014908	ENSCHIP00000006059	Uncharacterized protein.	Glutaminase 2.	0.508
ASL	GLUD1	ENSCHIP00000014908	ENSCHIP00000000388	Uncharacterized protein.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.536
ASL	GLUL	ENSCHIP00000014908	ENSCHIP00000030828	Uncharacterized protein.	Glutamine synthetase.	0.559
ASNS	CAD	ENSCHIP00000012001	ENSCHIP00000025740	Asparagine synthetase [glutamine-hydrolyzing].	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.916
ASNS	CTPS1	ENSCHIP00000012001	ENSCHIP00000032816	Asparagine synthetase [glutamine-hydrolyzing].	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.446
ASNS	ENSCHIP00000004162	ENSCHIP00000012001	ENSCHIP00000004162	Asparagine synthetase [glutamine-hydrolyzing].	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.474
ASNS	ENSCHIP00000011073	ENSCHIP00000012001	ENSCHIP00000011073	Asparagine synthetase [glutamine-hydrolyzing].	Uncharacterized protein.	0.488
ASNS	GLUD1	ENSCHIP00000012001	ENSCHIP00000000388	Asparagine synthetase [glutamine-hydrolyzing].	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.474
ASNS	GLUL	ENSCHIP00000012001	ENSCHIP00000030828	Asparagine synthetase [glutamine-hydrolyzing].	Glutamine synthetase.	0.548
ASNS	GMPS	ENSCHIP00000012001	ENSCHIP00000026603	Asparagine synthetase [glutamine-hydrolyzing].	Guanine monophosphate synthase.	0.449
ASNS	PHGDH	ENSCHIP00000012001	ENSCHIP00000019405	Asparagine synthetase [glutamine-hydrolyzing].	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.818
ASNSD1	ENSCHIP00000004162	ENSCHIP00000027061	ENSCHIP00000004162	Glutamine amidotransferase type-2 domain-containing protein.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.429
ASNSD1	ENSCHIP00000011073	ENSCHIP00000027061	ENSCHIP00000011073	Glutamine amidotransferase type-2 domain-containing protein.	Uncharacterized protein.	0.429
ASNSD1	GLUD1	ENSCHIP00000027061	ENSCHIP00000000388	Glutamine amidotransferase type-2 domain-containing protein.	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.429
ASNSD1	GLUL	ENSCHIP00000027061	ENSCHIP00000030828	Glutamine amidotransferase type-2 domain-containing protein.	Glutamine synthetase.	0.429
CAD	ASL	ENSCHIP00000025740	ENSCHIP00000014908	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Uncharacterized protein.	0.775
CAD	ASNS	ENSCHIP00000025740	ENSCHIP00000012001	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Asparagine synthetase [glutamine-hydrolyzing].	0.916