12 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCHIP00000028513	Uncharacterized protein. (129 aa)
	ENSCHIP00000024573	Uncharacterized protein. (60 aa)
	PCBD1	Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa)
	LOC102169668	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (188 aa)
	DHFR	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
	GCH1	GTP cyclohydrolase 1. (248 aa)
	QDPR	Quinoid dihydropteridine reductase. (242 aa)
	ENSCHIP00000021405	DHFR domain-containing protein. (156 aa)
	PTS	6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
	LOC108634131	Uncharacterized protein. (125 aa)
	SPR	Sepiapterin reductase. (267 aa)
	PCBD2	Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR	GCH1	ENSCHIP00000015609	ENSCHIP00000020290	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	GTP cyclohydrolase 1.	0.751
DHFR	QDPR	ENSCHIP00000015609	ENSCHIP00000006722	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Quinoid dihydropteridine reductase.	0.949
DHFR	SPR	ENSCHIP00000015609	ENSCHIP00000028646	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Sepiapterin reductase.	0.941
ENSCHIP00000024573	QDPR	ENSCHIP00000024573	ENSCHIP00000006722	Uncharacterized protein.	Quinoid dihydropteridine reductase.	0.549
ENSCHIP00000024573	SPR	ENSCHIP00000024573	ENSCHIP00000028646	Uncharacterized protein.	Sepiapterin reductase.	0.485
ENSCHIP00000028513	GCH1	ENSCHIP00000028513	ENSCHIP00000020290	Uncharacterized protein.	GTP cyclohydrolase 1.	0.808
ENSCHIP00000028513	SPR	ENSCHIP00000028513	ENSCHIP00000028646	Uncharacterized protein.	Sepiapterin reductase.	0.682
GCH1	DHFR	ENSCHIP00000020290	ENSCHIP00000015609	GTP cyclohydrolase 1.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.751
GCH1	ENSCHIP00000028513	ENSCHIP00000020290	ENSCHIP00000028513	GTP cyclohydrolase 1.	Uncharacterized protein.	0.808
GCH1	LOC108634131	ENSCHIP00000020290	ENSCHIP00000030316	GTP cyclohydrolase 1.	Uncharacterized protein.	0.808
GCH1	PTS	ENSCHIP00000020290	ENSCHIP00000031005	GTP cyclohydrolase 1.	6-pyruvoyl tetrahydrobiopterin synthase.	0.984
GCH1	QDPR	ENSCHIP00000020290	ENSCHIP00000006722	GTP cyclohydrolase 1.	Quinoid dihydropteridine reductase.	0.500
GCH1	SPR	ENSCHIP00000020290	ENSCHIP00000028646	GTP cyclohydrolase 1.	Sepiapterin reductase.	0.727
LOC108634131	GCH1	ENSCHIP00000030316	ENSCHIP00000020290	Uncharacterized protein.	GTP cyclohydrolase 1.	0.808
LOC108634131	SPR	ENSCHIP00000030316	ENSCHIP00000028646	Uncharacterized protein.	Sepiapterin reductase.	0.682
PCBD1	PCBD2	ENSCHIP00000023608	ENSCHIP00000028161	Pterin-4 alpha-carbinolamine dehydratase 1.	Pterin-4 alpha-carbinolamine dehydratase 2.	0.926
PCBD1	QDPR	ENSCHIP00000023608	ENSCHIP00000006722	Pterin-4 alpha-carbinolamine dehydratase 1.	Quinoid dihydropteridine reductase.	0.958
PCBD1	SPR	ENSCHIP00000023608	ENSCHIP00000028646	Pterin-4 alpha-carbinolamine dehydratase 1.	Sepiapterin reductase.	0.549
PCBD2	PCBD1	ENSCHIP00000028161	ENSCHIP00000023608	Pterin-4 alpha-carbinolamine dehydratase 2.	Pterin-4 alpha-carbinolamine dehydratase 1.	0.926
PCBD2	QDPR	ENSCHIP00000028161	ENSCHIP00000006722	Pterin-4 alpha-carbinolamine dehydratase 2.	Quinoid dihydropteridine reductase.	0.950