STRINGSTRING
ENKUR ENKUR ENG ENG LOC102174584 LOC102174584 CCDC39 CCDC39 AHI1 AHI1 PSEN1 PSEN1 TMEM107 TMEM107 DNAI2 DNAI2 MICAL2 MICAL2 APLNR APLNR LBX1 LBX1 MKS1 MKS1 SHH SHH SMO SMO PSKH1 PSKH1 ACVR1 ACVR1 NOTCH2 NOTCH2 CLUAP1 CLUAP1 IFT52 IFT52 SUFU SUFU TBC1D32 TBC1D32 ZIC3 ZIC3 AP1B1 AP1B1 FOLR1 FOLR1 NOTCH1 NOTCH1 DNAH5 DNAH5 SOX17 SOX17 DPCD DPCD DLL1 DLL1 CC2D2A CC2D2A PKD2 PKD2 C15orf65 C15orf65 TDGF1 TDGF1 FOXF1 FOXF1 IFT57 IFT57 ENSCHIP00000017332 ENSCHIP00000017332 IFT140 IFT140 FGF8 FGF8 CFAP45 CFAP45 DNAAF2 DNAAF2 DNAAF4 DNAAF4 PCSK6 PCSK6 CER1 CER1 RPGRIP1L RPGRIP1L IHH IHH DISP1 DISP1 MEF2C MEF2C WNT3A WNT3A WNT5A WNT5A ALG5 ALG5 NPHP3 NPHP3 HIF1A HIF1A ARL13B ARL13B FOXH1 FOXH1 TTC25 TTC25 C9orf116 C9orf116 CCDC103 CCDC103 DNAI1 DNAI1 MEGF8 MEGF8 NEK8 NEK8 DAAM2 DAAM2 SMAD3 SMAD3 TBX6 TBX6 ANKS6 ANKS6 ENSCHIP00000010134 ENSCHIP00000010134 FGF10 FGF10 HAND2 HAND2 TBX3 TBX3 ENSCHIP00000009368 ENSCHIP00000009368 SRF SRF ENSCHIP00000008875 ENSCHIP00000008875 TGFBR2 TGFBR2 DNAH11 DNAH11 TBX20 TBX20 TBXT TBXT NKX3-2 NKX3-2 DNAAF3 DNAAF3 FOXJ1 FOXJ1 C2CD3 C2CD3 ASB2 ASB2 RTTN RTTN BICC1 BICC1 IFT74 IFT74 LRRC6 LRRC6 CFAP52 CFAP52 MESP1 MESP1 IER2 IER2 DNAAF1 DNAAF1 DYNC2LI1 DYNC2LI1 CCDC40 CCDC40 ARMC4 ARMC4 PCSK5 PCSK5 GJA1 GJA1 HAND1 HAND1 MIB1 MIB1 DRC1 DRC1 NODAL NODAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
ENGEndoglin. (649 aa)
LOC102174584EGF-like domain-containing protein. (208 aa)
CCDC39Coiled-coil domain containing 39. (931 aa)
AHI1Abelson helper integration site 1. (1194 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa)
TMEM107Transmembrane protein 107. (140 aa)
DNAI2Dynein axonemal intermediate chain 2. (514 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1122 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LBX1Ladybird homeobox 1. (281 aa)
MKS1MKS transition zone complex subunit 1. (645 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NOTCH2Notch receptor 2. (2471 aa)
CLUAP1Clusterin associated protein 1. (438 aa)
IFT52Intraflagellar transport 52. (448 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
TBC1D32TBC1 domain family member 32. (1300 aa)
ZIC3Zic family member 3. (465 aa)
AP1B1AP complex subunit beta. (946 aa)
FOLR1Folate_rec domain-containing protein. (251 aa)
NOTCH1Notch receptor 1. (2508 aa)
DNAH5Dynein axonemal heavy chain 5. (4619 aa)
SOX17SRY-box transcription factor 17. (410 aa)
DPCDDeleted in primary ciliary dyskinesia homolog (mouse). (203 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1616 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (978 aa)
C15orf65Chromosome 15 open reading frame 65. (122 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (186 aa)
FOXF1Forkhead box F1. (391 aa)
IFT57Intraflagellar transport 57. (429 aa)
ENSCHIP00000017332Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (185 aa)
IFT140Intraflagellar transport 140. (1457 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
CFAP45Cilia and flagella associated protein 45. (549 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (828 aa)
DNAAF4Dynein axonemal assembly factor 4. (421 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (965 aa)
CER1Cerberus 1, DAN family BMP antagonist. (263 aa)
RPGRIP1LRPGRIP1 like. (1295 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
DISP1Dispatched RND transporter family member 1. (1555 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
ALG5ALG5 dolichyl-phosphate beta-glucosyltransferase. (324 aa)
NPHP3TPR_REGION domain-containing protein. (1325 aa)
HIF1AUncharacterized protein. (823 aa)
ARL13BADP ribosylation factor like GTPase 13B. (429 aa)
FOXH1Forkhead box H1. (360 aa)
TTC25Tetratricopeptide repeat domain 25. (650 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
CCDC103Coiled-coil domain containing 103. (235 aa)
DNAI1Dynein axonemal intermediate chain 1. (701 aa)
MEGF8Multiple EGF like domains 8. (2836 aa)
NEK8NIMA related kinase 8. (696 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1087 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TBX6T-box transcription factor 6. (437 aa)
ANKS6Ankyrin repeat and sterile alpha motif domain containing 6. (873 aa)
ENSCHIP00000010134CFC domain-containing protein. (159 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
TBX3T-box transcription factor 3. (749 aa)
ENSCHIP00000009368Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (185 aa)
SRFSerum response factor. (509 aa)
ENSCHIP00000008875BMERB domain-containing protein. (705 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
DNAH11Dynein axonemal heavy chain 11. (4508 aa)
TBX20T-box transcription factor 20. (449 aa)
TBXTT-box transcription factor T. (435 aa)
NKX3-2NK3 homeobox 2. (330 aa)
DNAAF3Uncharacterized protein. (542 aa)
FOXJ1Forkhead box J1. (421 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2333 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (633 aa)
RTTNRotatin. (2228 aa)
BICC1BicC family RNA binding protein 1. (972 aa)
IFT74Intraflagellar transport 74. (600 aa)
LRRC6Leucine rich repeat containing 6. (474 aa)
CFAP52Cilia and flagella associated protein 52. (623 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (256 aa)
IER2Immediate early response 2. (224 aa)
DNAAF1Dynein assembly factor 1, axonemal. (643 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (353 aa)
CCDC40Coiled-coil domain containing 40. (937 aa)
ARMC4Armadillo repeat containing 4. (1045 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1884 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
DRC1Dynein regulatory complex subunit 1. (770 aa)
NODALNodal growth differentiation factor. (346 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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