(14 nodes) Specification of animal organ identity network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ISL1	ISL LIM homeobox 1. (349 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
	LRP2	LDL receptor related protein 2. (4649 aa)
	GLI3	GLI family zinc finger 3. (1614 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	FOXH1	Forkhead box H1. (360 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	MEF2C	MADS-box domain-containing protein. (441 aa)
	AXIN2	Axin 2. (844 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (256 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	BMP4	ENSCHIP00000022676	ENSCHIP00000023678	Axin 2.	Bone morphogenetic protein 4.	0.715
AXIN2	FGF10	ENSCHIP00000022676	ENSCHIP00000010028	Axin 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.417
AXIN2	GLI3	ENSCHIP00000022676	ENSCHIP00000014153	Axin 2.	GLI family zinc finger 3.	0.489
AXIN2	LRP2	ENSCHIP00000022676	ENSCHIP00000020275	Axin 2.	LDL receptor related protein 2.	0.488
AXIN2	WNT11	ENSCHIP00000022676	ENSCHIP00000024696	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.772
AXIN2	WNT5A	ENSCHIP00000022676	ENSCHIP00000015533	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.893
BMP4	AXIN2	ENSCHIP00000023678	ENSCHIP00000022676	Bone morphogenetic protein 4.	Axin 2.	0.715
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	FOXH1	ENSCHIP00000023678	ENSCHIP00000014519	Bone morphogenetic protein 4.	Forkhead box H1.	0.427
BMP4	GLI3	ENSCHIP00000023678	ENSCHIP00000014153	Bone morphogenetic protein 4.	GLI family zinc finger 3.	0.499
BMP4	ISL1	ENSCHIP00000023678	ENSCHIP00000025978	Bone morphogenetic protein 4.	ISL LIM homeobox 1.	0.733
BMP4	MEF2C	ENSCHIP00000023678	ENSCHIP00000015775	Bone morphogenetic protein 4.	MADS-box domain-containing protein.	0.577
BMP4	WNT11	ENSCHIP00000023678	ENSCHIP00000024696	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
BMP4	WNT5A	ENSCHIP00000023678	ENSCHIP00000015533	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.731
FGF10	AXIN2	ENSCHIP00000010028	ENSCHIP00000022676	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Axin 2.	0.417
FGF10	BMP4	ENSCHIP00000010028	ENSCHIP00000023678	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.887
FGF10	GLI3	ENSCHIP00000010028	ENSCHIP00000014153	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GLI family zinc finger 3.	0.421
FGF10	ISL1	ENSCHIP00000010028	ENSCHIP00000025978	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	ISL LIM homeobox 1.	0.561
FGF10	WNT11	ENSCHIP00000010028	ENSCHIP00000024696	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.541
FGF10	WNT5A	ENSCHIP00000010028	ENSCHIP00000015533	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.584