STRINGSTRING
ATG101 ATG101 ATG2A ATG2A NPRL2 NPRL2 PRKD1 PRKD1 VPS13D VPS13D VDAC1 VDAC1 SCOC SCOC ENSCHIP00000029131 ENSCHIP00000029131 TRIM21 TRIM21 GNAI3 GNAI3 NOD2 NOD2 ENSCHIP00000030535 ENSCHIP00000030535 CALCOCO2 CALCOCO2 TP53INP2 TP53INP2 SESN3 SESN3 PINK1 PINK1 FBXO7 FBXO7 TRIML1 TRIML1 PLK2 PLK2 ENSCHIP00000032547 ENSCHIP00000032547 ATG16L1 ATG16L1 SH3GLB1 SH3GLB1 HTT HTT ORMDL3 ORMDL3 TRIM68 TRIM68 RNF31 RNF31 GSK3A GSK3A FLCN FLCN TPCN1 TPCN1 TRIM8 TRIM8 RAB3GAP2 RAB3GAP2 NPRL3 NPRL3 SNX4 SNX4 DAPK1 DAPK1 SH3BP4 SH3BP4 WDR45 WDR45 CDK16 CDK16 TSC2 TSC2 PAFAH1B2 PAFAH1B2 LARP1 LARP1 PRKAA2 PRKAA2 ATG13 ATG13 TFEB TFEB C9orf72 C9orf72 ENSCHIP00000013480 ENSCHIP00000013480 ENSCHIP00000013894 ENSCHIP00000013894 TRIM6 TRIM6 KAT5 KAT5 HSPB8 HSPB8 HIF1A HIF1A LOC102169889 LOC102169889 MAPK3 MAPK3 ROCK1 ROCK1 PARK2 PARK2 DEPDC5 DEPDC5 IFNG IFNG DHRSX DHRSX SPTLC1 SPTLC1 HMOX1 HMOX1 UFL1 UFL1 BNIP3 BNIP3 AMBRA1 AMBRA1 SUPT5H SUPT5H SESN2 SESN2 EPM2A EPM2A BTNL9 BTNL9 PIP4K2B PIP4K2B TBK1 TBK1 PIP4K2A PIP4K2A WAC WAC WDR24 WDR24 LOC102173185 LOC102173185 TRIM65 TRIM65 ZC3H12A ZC3H12A SPTLC2 SPTLC2 LRRK2 LRRK2 STK11 STK11 LOC102170165 LOC102170165 BECN1 BECN1 CERS1 CERS1 SNX18 SNX18 ENSCHIP00000023383 ENSCHIP00000023383 MID2 MID2 LOC102170446 LOC102170446 ENDOG ENDOG SMCR8 SMCR8 MTDH MTDH NOD1 NOD1 BAG3 BAG3 IL4 IL4 RALB RALB TRIM38 TRIM38 ULK1 ULK1 SVIP SVIP ENSCHIP00000000605 ENSCHIP00000000605 ENSCHIP00000000923 ENSCHIP00000000923 PLK3 PLK3 TRIML2 TRIML2 SNX30 SNX30 PLEKHF1 PLEKHF1 RAB3GAP1 RAB3GAP1 KDR KDR ENSCHIP00000003779 ENSCHIP00000003779 ENSCHIP00000003952 ENSCHIP00000003952 FYCO1 FYCO1 MID2-2 MID2-2 CCNY CCNY TP53INP1 TP53INP1 TRIM27 TRIM27 TRIM32 TRIM32 ENSCHIP00000006356 ENSCHIP00000006356 PIP4K2C PIP4K2C STING1 STING1 TMEM59 TMEM59 TRIM13 TRIM13 SIRT1 SIRT1 RNF152 RNF152 LRSAM1 LRSAM1 RIPK2 RIPK2 ATF6 ATF6 FOXO3 FOXO3 FOXO1 FOXO1 WIPI1 WIPI1 DCN DCN SESN1 SESN1 RB1CC1 RB1CC1 PRKAA1 PRKAA1 SNX7 SNX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG101Autophagy related 101. (218 aa)
ATG2AAutophagy related 2A. (1927 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (380 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4396 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
SCOCShort coiled-coil protein. (159 aa)
ENSCHIP00000029131RUN domain-containing protein. (181 aa)
TRIM21Tripartite motif containing 21. (465 aa)
GNAI3G protein subunit alpha i3. (354 aa)
NOD2Uncharacterized protein. (982 aa)
ENSCHIP00000030535zf-RING_14 domain-containing protein. (149 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (448 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (224 aa)
SESN3Sestrin 3. (492 aa)
PINK1PTEN induced kinase 1. (587 aa)
FBXO7F-box protein 7. (523 aa)
TRIML1Tripartite motif family like 1. (474 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
ENSCHIP00000032547APG6 domain-containing protein. (249 aa)
ATG16L1Autophagy related 16 like 1. (607 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (402 aa)
HTTUncharacterized protein. (2830 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
TRIM68Tripartite motif containing 68. (494 aa)
RNF31Uncharacterized protein. (1066 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
TPCN1Two pore segment channel 1. (818 aa)
TRIM8Tripartite motif containing 8. (551 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1392 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
SNX4Sorting nexin 4. (450 aa)
DAPK1Death associated protein kinase 1. (1440 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
WDR45Uncharacterized protein. (360 aa)
CDK16Cyclin dependent kinase 16. (491 aa)
TSC2Rap-GAP domain-containing protein. (1817 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
LARP1La ribonucleoprotein domain family member 1. (1144 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (517 aa)
TFEBTranscription factor EB. (478 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
ENSCHIP00000013480PX domain-containing protein. (325 aa)
ENSCHIP00000013894Uncharacterized protein. (463 aa)
TRIM6Tripartite motif containing 6. (487 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
HIF1AUncharacterized protein. (823 aa)
LOC102169889TRIM5 alpha. (509 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PARK2Ubiquitin-like domain-containing protein. (293 aa)
DEPDC5DEP domain-containing protein. (1563 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
DHRSXDehydrogenase/reductase X-linked. (335 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (480 aa)
HMOX1Heme oxygenase 1. (288 aa)
UFL1UFM1 specific ligase 1. (792 aa)
BNIP3BCL2 interacting protein 3. (193 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1300 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
SESN2Sestrin 2. (471 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
BTNL9Butyrophilin like 9. (538 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
TBK1TANK binding kinase 1. (734 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa)
WACWW domain containing adaptor with coiled-coil. (647 aa)
WDR24WD repeat domain 24. (790 aa)
LOC102173185Uncharacterized protein. (509 aa)
TRIM65Tripartite motif containing 65. (511 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (562 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
LOC102170165Uncharacterized protein. (475 aa)
BECN1Uncharacterized protein. (448 aa)
CERS1TLC domain-containing protein. (333 aa)
SNX18Sorting nexin. (626 aa)
ENSCHIP00000023383RBR-type E3 ubiquitin transferase. (84 aa)
MID2Midline 2. (463 aa)
LOC102170446Uncharacterized protein. (489 aa)
ENDOGEndonuclease. (299 aa)
SMCR8SMCR8-C9orf72 complex subunit. (938 aa)
MTDHMetadherin. (583 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
BAG3BCL2 associated athanogene 3. (576 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
RALBRAS like proto-oncogene B. (206 aa)
TRIM38Tripartite motif containing 38. (460 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
SVIPSmall VCP interacting protein. (77 aa)
ENSCHIP00000000605Uncharacterized protein. (418 aa)
ENSCHIP00000000923Uncharacterized protein. (467 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
TRIML2Tripartite motif family like 2. (438 aa)
SNX30Sorting nexin family member 30. (437 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (279 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
ENSCHIP00000003779Uncharacterized protein. (330 aa)
ENSCHIP00000003952B30.2/SPRY domain-containing protein. (197 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1438 aa)
MID2-2RING-type domain-containing protein. (240 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
TRIM27Tripartite motif containing 27. (513 aa)
TRIM32Tripartite motif containing 32. (695 aa)
ENSCHIP00000006356Uncharacterized protein. (101 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
STING1Transmembrane protein 173. (378 aa)
TMEM59Transmembrane protein 59. (335 aa)
TRIM13Tripartite motif containing 13. (407 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
RNF152Ring finger protein 152. (204 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (728 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
ATF6Activating transcription factor 6. (664 aa)
FOXO3Forkhead box O3. (672 aa)
FOXO1Forkhead box O1. (668 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (447 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
SESN1Sestrin 1. (552 aa)
RB1CC1RB1 inducible coiled-coil 1. (1589 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
SNX7PX domain-containing protein. (471 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.