STRINGSTRING
ADPRHL1 ADPRHL1 BMPR1A BMPR1A LRRC10B LRRC10B HAND1 HAND1 POU4F1 POU4F1 TCAP TCAP ENSCHIP00000002011 ENSCHIP00000002011 ACTC1 ACTC1 LRRC10 LRRC10 HNRNPU HNRNPU PDGFRA PDGFRA PGM5 PGM5 JARID2 JARID2 VWA5B2 VWA5B2 MESP1 MESP1 TREX1 TREX1 BVES BVES S1PR1 S1PR1 GJC1 GJC1 NOG NOG BMP7 BMP7 CAV3 CAV3 ACTN2 ACTN2 ZFPM1 ZFPM1 ASB2 ASB2 GREM1 GREM1 MYH11 MYH11 EYA2 EYA2 ARID2 ARID2 SGCG SGCG ITGB1 ITGB1 WNT2 WNT2 SGCZ SGCZ TBX20 TBX20 SMAD1 SMAD1 IFT20 IFT20 PRKAR1A PRKAR1A PLN PLN CHD7 CHD7 RARB RARB TGFB1 TGFB1 TBX18 TBX18 SRF SRF TBX3 TBX3 ENSCHIP00000009957 ENSCHIP00000009957 SAV1 SAV1 BMP2 BMP2 SIK1 SIK1 NPRL3 NPRL3 DSP DSP MYL3 MYL3 CDC42 CDC42 ZMPSTE24 ZMPSTE24 NEB NEB TBX2 TBX2 GATA5 GATA5 PKP2 PKP2 CBY1 CBY1 RARA RARA LOC102181663 LOC102181663 IRX3 IRX3 PRMT1 PRMT1 ENSCHIP00000013896 ENSCHIP00000013896 DLL4 DLL4 FOXH1 FOXH1 NDUFV2 NDUFV2 ZFPM2 ZFPM2 ALPK3 ALPK3 EGLN1 EGLN1 SHOX2 SHOX2 WNT5A WNT5A WNT3A WNT3A DSG2 DSG2 MEF2C MEF2C TNNI1 TNNI1 ENSCHIP00000016978 ENSCHIP00000016978 MYLK2 MYLK2 SEMA3C SEMA3C KDM6B KDM6B MYH6 MYH6 NKX2-5 NKX2-5 ENSCHIP00000018633 ENSCHIP00000018633 TSC1 TSC1 MAPK11 MAPK11 ANKRD1 ANKRD1 GATA6 GATA6 DIPK2A DIPK2A LRP2 LRP2 SMAD4 SMAD4 TNNC1 TNNC1 SGCD SGCD SMAD7 SMAD7 MYLK3 MYLK3 ATG5 ATG5 VWA5A VWA5A EDNRA EDNRA MTOR MTOR NRAP NRAP TNNT2 TNNT2 FGF9 FGF9 ADRA1A ADRA1A BMP4 BMP4 NOTCH1 NOTCH1 MYOCD MYOCD MYH7 MYH7 PROX1 PROX1 NOX4 NOX4 ZIC3 ZIC3 EYA1 EYA1 MYL7 MYL7 MYBPC3 MYBPC3 FHOD3 FHOD3 PLEC PLEC TGFBR1 TGFBR1 ISL1 ISL1 CXADR CXADR TGFB2 TGFB2 LMNA LMNA CSRP3 CSRP3 NEBL-2 NEBL-2 NKX2-6 NKX2-6 MYO18B MYO18B SHH SHH NEBL NEBL SLC9A1 SLC9A1 VWA5B1 VWA5B1 TBX5 TBX5 MED1 MED1 ADPRH ADPRH ALPK2 ALPK2 MEF2A MEF2A ENSCHIP00000029659 ENSCHIP00000029659 MAML1 MAML1 MYL10 MYL10 FHL2 FHL2 PPP1R13L PPP1R13L ALDH1A2 ALDH1A2 ENSCHIP00000031821 ENSCHIP00000031821 BMP10 BMP10 ENG ENG HEY2 HEY2 TENM4 TENM4 IFRD2 IFRD2 RYR2 RYR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADPRHL1ADP-ribosylhydrolase like 1. (354 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
POU4F1POU domain protein. (421 aa)
TCAPUncharacterized protein. (167 aa)
ENSCHIP00000002011Formin_GBD_N domain-containing protein. (88 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
LRRC10Leucine rich repeat containing 10. (279 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1258 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1254 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (256 aa)
TREX1Three prime repair exonuclease 1. (315 aa)
BVESBlood vessel epicardial substance. (360 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ACTN2Actinin alpha 2. (902 aa)
ZFPM1Zinc finger protein, FOG family member 1. (988 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (633 aa)
GREM1Gremlin. (184 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (552 aa)
ARID2AT-rich interaction domain 2. (1835 aa)
SGCGSarcoglycan gamma. (291 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SGCZSarcoglycan zeta. (264 aa)
TBX20T-box transcription factor 20. (449 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
IFT20Intraflagellar transport 20. (156 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (380 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2993 aa)
RARBRetinoic acid receptor beta. (448 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TBX18T-box transcription factor 18. (612 aa)
SRFSerum response factor. (509 aa)
TBX3T-box transcription factor 3. (749 aa)
ENSCHIP00000009957Calponin-homology (CH) domain-containing protein. (123 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
SIK1Uncharacterized protein. (778 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
DSPDesmoplakin. (2892 aa)
MYL3Myosin light chain 3. (194 aa)
CDC42Uncharacterized protein. (191 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
NEBNebulin. (6655 aa)
TBX2T-box transcription factor 2. (771 aa)
GATA5GATA binding protein 5. (403 aa)
PKP2Plakophilin 2. (851 aa)
CBY1Uncharacterized protein. (127 aa)
RARARetinoic acid receptor alpha. (462 aa)
LOC102181663Uncharacterized protein. (119 aa)
IRX3Iroquois homeobox 3. (503 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
ENSCHIP00000013896Uncharacterized protein. (179 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
FOXH1Forkhead box H1. (360 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1022 aa)
ALPK3Alpha kinase 3. (1840 aa)
EGLN1Uncharacterized protein. (422 aa)
SHOX2Short stature homeobox 2. (319 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
DSG2Desmoglein 2. (1119 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
ENSCHIP00000016978Uncharacterized protein. (243 aa)
MYLK2Myosin light chain kinase 2. (632 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (765 aa)
KDM6BLysine demethylase 6B. (1685 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
NKX2-5NK2 homeobox 5. (323 aa)
ENSCHIP00000018633Uncharacterized protein. (240 aa)
TSC1Uncharacterized protein. (1158 aa)
MAPK11Mitogen-activated protein kinase. (417 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
GATA6GATA binding protein 6. (592 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
LRP2LDL receptor related protein 2. (4649 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
TNNC1Uncharacterized protein. (154 aa)
SGCDSarcoglycan delta. (289 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
MYLK3Myosin light chain kinase 3. (786 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
VWA5AVon Willebrand factor A domain containing 5A. (783 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
NRAPNebulin related anchoring protein. (1730 aa)
TNNT2Troponin T2, cardiac type. (267 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
MYOCDMyocardin. (982 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
PROX1Prospero homeobox 1. (734 aa)
NOX4NADPH oxidase 4. (578 aa)
ZIC3Zic family member 3. (465 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
MYL7Myosin light chain 7. (175 aa)
MYBPC3Myosin binding protein C, cardiac. (1303 aa)
FHOD3Formin homology 2 domain containing 3. (1541 aa)
PLECPlectin. (4150 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ISL1ISL LIM homeobox 1. (349 aa)
CXADRUncharacterized protein. (416 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
NEBL-2Uncharacterized protein. (270 aa)
NKX2-6NK2 homeobox 6. (300 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2518 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
NEBLNebulette. (662 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1183 aa)
TBX5T-box transcription factor 5. (594 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1577 aa)
ADPRHADP-ribosylarginine hydrolase. (354 aa)
ALPK2Alpha kinase 2. (2148 aa)
MEF2AMADS-box domain-containing protein. (500 aa)
ENSCHIP00000029659Uncharacterized protein. (202 aa)
MAML1Mastermind like transcriptional coactivator 1. (1018 aa)
MYL10Myosin light chain 10. (222 aa)
FHL2Four and a half LIM domains 2. (279 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (823 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSCHIP00000031821Uncharacterized protein. (189 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ENGEndoglin. (649 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TENM4Teneurin transmembrane protein 4. (2855 aa)
IFRD2Interferon related developmental regulator 2. (442 aa)
RYR2Ryanodine receptor 2. (4943 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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