STRINGSTRING
SMYD3-2 SMYD3-2 CAV2 CAV2 KLF5 KLF5 ENSCHIP00000009957 ENSCHIP00000009957 SIX4 SIX4 CD9 CD9 RIPOR2 RIPOR2 CDON CDON DOCK5 DOCK5 STAC3 STAC3 PPP3CB PPP3CB SKI SKI SORT1 SORT1 ITGB1 ITGB1 WNT10B WNT10B CAV3 CAV3 MYORG MYORG BCL9 BCL9 MYOD1 MYOD1 CD81 CD81 P2RX2 P2RX2 SMO SMO SHH SHH KEL KEL ENSCHIP00000028617 ENSCHIP00000028617 PLD3 PLD3 SIX1 SIX1 MYMK MYMK ADAMTS15 ADAMTS15 KLHL41 KLHL41 CNTNAP1 CNTNAP1 BARX2 BARX2 PLEC PLEC PLEKHO1 PLEKHO1 DOCK2 DOCK2 HOMER1 HOMER1 FER1L5 FER1L5 TANC1 TANC1 PPP3CA PPP3CA BIN3 BIN3 ENSCHIP00000023179 ENSCHIP00000023179 TMEM182 TMEM182 SELENON SELENON SMYD3 SMYD3 DNER DNER MYH9 MYH9 DOCK1 DOCK1 WNT1 WNT1 ADAMTS5 ADAMTS5 IGF1 IGF1 CAPN2 CAPN2 ACTA2 ACTA2 PTGFRN PTGFRN LMOD3 LMOD3 MYOF MYOF SPG11 SPG11 BCL2 BCL2 MEF2C MEF2C ACTN1 ACTN1 ADGRB3 ADGRB3 NPHS1 NPHS1 KLHL40 KLHL40 R3HDM2 R3HDM2 C9orf24 C9orf24 DYRK1B DYRK1B CACNA1S CACNA1S NFATC2 NFATC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMYD3-2MYND-type domain-containing protein. (159 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
KLF5Uncharacterized protein. (454 aa)
ENSCHIP00000009957Calponin-homology (CH) domain-containing protein. (123 aa)
SIX4SIX homeobox 4. (784 aa)
CD9Tetraspanin. (226 aa)
RIPOR2Uncharacterized protein. (1052 aa)
CDONCell adhesion associated, oncogene regulated. (1254 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1869 aa)
STAC3SH3 and cysteine rich domain 3. (357 aa)
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
SKISKI proto-oncogene. (729 aa)
SORT1Sortilin. (832 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
CD81Tetraspanin. (236 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (479 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
KELKell metallo-endopeptidase (Kell blood group). (703 aa)
ENSCHIP00000028617Uncharacterized protein. (75 aa)
PLD3Phospholipase D family member 3. (490 aa)
SIX1SIX homeobox 1. (284 aa)
MYMKMyomaker, myoblast fusion factor. (221 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (939 aa)
KLHL41Kelch like family member 41. (606 aa)
CNTNAP1Contactin associated protein 1. (1396 aa)
BARX2BARX homeobox 2. (278 aa)
PLECPlectin. (4150 aa)
PLEKHO1Pleckstrin homology domain containing O1. (409 aa)
DOCK2DHR-1 domain-containing protein; Belongs to the DOCK family. (846 aa)
HOMER1Homer scaffold protein 1. (359 aa)
FER1L5Fer-1 like family member 5. (1921 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1851 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
BIN3Bridging integrator 3. (253 aa)
ENSCHIP00000023179Uncharacterized protein. (330 aa)
TMEM182Transmembrane protein 182. (229 aa)
SELENONSelenoprotein N. (579 aa)
SMYD3SET and MYND domain containing 3. (301 aa)
DNERDelta/notch like EGF repeat containing. (728 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1888 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (934 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
PTGFRNProstaglandin F2 receptor inhibitor. (879 aa)
LMOD3Leiomodin 3. (567 aa)
MYOFMyoferlin. (2025 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2432 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
ACTN1Actinin alpha 1. (914 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1282 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1233 aa)
KLHL40Kelch like family member 40. (596 aa)
R3HDM2Uncharacterized protein. (1033 aa)
C9orf24Chromosome 9 open reading frame 24. (304 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1809 aa)
NFATC2Nuclear factor of activated T cells 2. (914 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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