Your Input: | |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2534 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1062 aa) |
| | TMEM41B | Transmembrane protein 41B. (291 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | UBXN2B | UBX domain protein 2B. (318 aa) |
| | GAA | Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (935 aa) |
| | PARK2 | Ubiquitin-like domain-containing protein. (293 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | UFL1 | UFM1 specific ligase 1. (792 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (101 aa) |
| | SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2432 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1300 aa) |
| | HDAC10 | Histone deacetylase 10. (672 aa) |
| | MTM1 | Myotubularin 1. (621 aa) |
| | ATG2A | Autophagy related 2A. (1927 aa) |
| | PHB2 | Prohibitin. (289 aa) |
| | ATG101 | Autophagy related 101. (218 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) |
| | SNX7 | PX domain-containing protein. (471 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (441 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (410 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1589 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (472 aa) |
| | SNX14 | Sorting nexin 14. (966 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (731 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (376 aa) |
| | LOC102176530 | Uncharacterized protein. (296 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (447 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (816 aa) |
| | SNAP29 | Synaptosome associated protein 29. (258 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | LOC108635484 | Protein kinase domain-containing protein. (677 aa) |
| | WDR45B | WD repeat domain 45B. (344 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (722 aa) |
| | ULK1 | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa) |
| | ENSCHIP00000020708 | Protein kinase domain-containing protein. (969 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (954 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | ENSCHIP00000021951 | Uncharacterized protein. (85 aa) |
| | RAB33B | RAB33B, member RAS oncogene family. (229 aa) |
| | UFC1 | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa) |
| | EI24 | Uncharacterized protein. (340 aa) |
| | CLN3 | Battenin. (442 aa) |
| | RAB1B | RAB1B, member RAS oncogene family. (201 aa) |
| | CHMP4A | Charged multivesicular body protein 4A. (222 aa) |
| | ATG2B | Autophagy related 2B. (2056 aa) |
| | ENSCHIP00000023383 | RBR-type E3 ubiquitin transferase. (84 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (404 aa) |
| | RETREG3 | Reticulophagy regulator family member 3. (466 aa) |
| | NPC1 | SSD domain-containing protein. (1297 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | BECN1 | Uncharacterized protein. (448 aa) |
| | RETREG1 | Reticulophagy regulator 1. (479 aa) |
| | LOC108635483 | Uncharacterized protein. (156 aa) |
| | ENSCHIP00000024900 | Autophagy_N domain-containing protein. (127 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) |
| | LGALS8 | Galectin. (319 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (331 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3509 aa) |
| | ATG10 | Autophagy related 10. (234 aa) |
| | ENSCHIP00000027249 | Protein kinase domain-containing protein. (292 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (988 aa) |
| | ULK3 | Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa) |
| | KIAA1324 | KIAA1324. (1013 aa) |
| | MAP1LC3C | Microtubule associated protein 1 light chain 3 gamma. (148 aa) |
| | MFSD8 | Major facilitator superfamily domain containing 8. (519 aa) |
| | ENSCHIP00000029131 | RUN domain-containing protein. (181 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (274 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (929 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | LOC102188868 | Uncharacterized protein. (222 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (117 aa) |
| | ENSCHIP00000030535 | zf-RING_14 domain-containing protein. (149 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1026 aa) |
| | CALCOCO2 | Calcium binding and coiled-coil domain 2. (448 aa) |
| | TECPR1 | Tectonin beta-propeller repeat containing 1. (1089 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (436 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (224 aa) |
| | ENSCHIP00000030862 | Uncharacterized protein. (274 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (247 aa) |
| | PINK1 | PTEN induced kinase 1. (587 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1310 aa) |
| | UVRAG | UV radiation resistance associated. (699 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | VMP1 | Vacuole membrane protein 1. (406 aa) |
| | ENSCHIP00000032031 | Uncharacterized protein. (135 aa) |
| | NSFL1C | NSFL1 cofactor. (372 aa) |
| | ENSCHIP00000032547 | APG6 domain-containing protein. (249 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (607 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | VTI1B | t-SNARE coiled-coil homology domain-containing protein. (232 aa) |
| | MAP1LC3B | Uncharacterized protein. (143 aa) |
| | WDR81 | WD repeat domain 81. (1932 aa) |
| | LIX1 | Limb and CNS expressed 1. (282 aa) |
| | ENSCHIP00000000416 | NPC1_N domain-containing protein. (171 aa) |
| | ENSCHIP00000000483 | Uncharacterized protein. (304 aa) |
| | C5orf51 | Chromosome 5 open reading frame 51. (293 aa) |
| | ATG16L2 | Autophagy related 16 like 2. (616 aa) |
| | RAB7A | Uncharacterized protein. (207 aa) |
| | TEX264 | Testis expressed 264, ER-phagy receptor. (314 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (213 aa) |
| | EPG5 | Ectopic P-granules autophagy protein 5 homolog. (2578 aa) |
| | SNX30 | Sorting nexin family member 30. (437 aa) |
| | MCOLN1 | Mucolipin 1. (580 aa) |
| | UBXN6 | UBX domain protein 6. (441 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (236 aa) |
| | RAB19 | RAB19, member RAS oncogene family. (227 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | ENSCHIP00000003525 | Uncharacterized protein. (344 aa) |
| | EMC6 | ER membrane protein complex subunit 6. (110 aa) |
| | TMEM74 | Transmembrane protein 74. (306 aa) |
| | UBXN2A | UBX domain protein 2A. (258 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | RETREG2 | Reticulophagy regulator family member 2. (540 aa) |
| | DDRGK1 | DDRGK domain containing 1. (298 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (237 aa) |
| | LOC102182337 | t-SNARE coiled-coil homology domain-containing protein. (227 aa) |
| | STING1 | Transmembrane protein 173. (378 aa) |
| | ATP13A2 | ATPase cation transporting 13A2. (1035 aa) |
| | TRAPPC8 | Trafficking protein particle complex 8. (1428 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (801 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (789 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | STBD1 | Starch binding domain 1. (334 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (662 aa) |
| | ENSCHIP00000009861 | Protein kinase domain-containing protein. (292 aa) |
| | LIX1L | Limb and CNS expressed 1 like. (337 aa) |
| | ENSCHIP00000009885 | Uncharacterized protein. (198 aa) |
| | GSAP | Gamma-secretase activating protein. (854 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (494 aa) |
| | UFM1 | Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes. (85 aa) |
| | ATG3 | Uncharacterized protein. (158 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (226 aa) |
| | YOD1 | YOD1 deubiquitinase. (348 aa) |
| | RAB1A | Uncharacterized protein. (206 aa) |
| | WDR45 | Uncharacterized protein. (360 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (517 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (875 aa) |
| | ENSCHIP00000013480 | PX domain-containing protein. (325 aa) |
| | PLAA | Phospholipase A2 activating protein. (796 aa) |
| | STX17 | Syntaxin 17; Belongs to the syntaxin family. (301 aa) |
| | UBQLN1 | Ubiquilin 1. (589 aa) |
| | ENSCHIP00000014358 | Uncharacterized protein. (90 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa) |
| | GABARAPL2 | Uncharacterized protein. (117 aa) |
| | ARFIP2 | ADP ribosylation factor interacting protein 2. (341 aa) |
