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APRT APRT ENSCHIP00000019684 ENSCHIP00000019684 TIPARP TIPARP PRTFDC1 PRTFDC1 VWA5A VWA5A SIRT2 SIRT2 GXYLT1 GXYLT1 QPRT QPRT POGLUT3 POGLUT3 TNKS2 TNKS2 LARGE2 LARGE2 ART3 ART3 ANKRD39 ANKRD39 ENSCHIP00000026638 ENSCHIP00000026638 LACC1 LACC1 VWA5B1 VWA5B1 XXYLT1 XXYLT1 POGLUT2 POGLUT2 PARP2 PARP2 FAM162A FAM162A ART5 ART5 UMPS UMPS ENSCHIP00000030793 ENSCHIP00000030793 LOC102169399 LOC102169399 ZC3HAV1 ZC3HAV1 SIRT6 SIRT6 XYLT1 XYLT1 PARP6 PARP6 LOC102178093 LOC102178093 CENPO CENPO QTRT1 QTRT1 PPAT PPAT NAMPT NAMPT FAM162B FAM162B POGLUT1 POGLUT1 PNP PNP PARP16 PARP16 GXYLT2 GXYLT2 ART1 ART1 ART4 ART4 LOC102176691 LOC102176691 PARP10 PARP10 TNKS TNKS VWA5B2 VWA5B2 ENSCHIP00000002983 ENSCHIP00000002983 LOC102169116 LOC102169116 SIRT4 SIRT4 NAPRT NAPRT UPP1 UPP1 PARP12 PARP12 MTAP MTAP MROH6 MROH6 LARGE1 LARGE1 HPRT1 HPRT1 PARP3 PARP3 PARP4 PARP4 PARP9 PARP9 QTRT2 QTRT2 PARP8 PARP8 RXYLT1 RXYLT1 UPP2 UPP2 PARP1 PARP1 PARP14 PARP14 XYLT2 XYLT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APRTAdenine phosphoribosyltransferase. (180 aa)
ENSCHIP00000019684Uncharacterized protein. (287 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (656 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
VWA5AVon Willebrand factor A domain containing 5A. (783 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
GXYLT1Glucoside xylosyltransferase 1. (485 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (295 aa)
POGLUT3Protein O-glucosyltransferase 3. (508 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
LARGE2LARGE xylosyl- and glucuronyltransferase 2. (724 aa)
ART3NAD(P)(+)--arginine ADP-ribosyltransferase. (387 aa)
ANKRD39Ankyrin repeat domain 39. (183 aa)
ENSCHIP00000026638Uncharacterized protein. (190 aa)
LACC1Uncharacterized protein. (426 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1183 aa)
XXYLT1Xyloside xylosyltransferase 1. (393 aa)
POGLUT2Protein O-glucosyltransferase 2. (502 aa)
PARP2Poly [ADP-ribose] polymerase. (533 aa)
FAM162AFamily with sequence similarity 162 member A. (154 aa)
ART5NAD(P)(+)--arginine ADP-ribosyltransferase. (311 aa)
UMPSUridine monophosphate synthetase. (507 aa)
ENSCHIP00000030793Amidophosphoribosyltransferase. (439 aa)
LOC102169399NAD(P)(+)--arginine ADP-ribosyltransferase. (314 aa)
ZC3HAV1Poly [ADP-ribose] polymerase. (892 aa)
SIRT6Sirtuin 6. (335 aa)
XYLT1Xylosyltransferase 1. (991 aa)
PARP6Poly [ADP-ribose] polymerase. (610 aa)
LOC102178093NAD(P)(+)--arginine ADP-ribosyltransferase. (310 aa)
CENPOUncharacterized protein. (296 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (514 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
FAM162BFamily with sequence similarity 162 member B. (163 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
PARP16Poly [ADP-ribose] polymerase. (324 aa)
GXYLT2Glucoside xylosyltransferase 2. (443 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (326 aa)
ART4NAD(P)(+)--arginine ADP-ribosyltransferase. (322 aa)
LOC102176691Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
PARP10Poly [ADP-ribose] polymerase. (969 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1254 aa)
ENSCHIP00000002983Glutamine amidotransferase type-2 domain-containing protein. (272 aa)
LOC102169116NAD(P)(+)--arginine ADP-ribosyltransferase. (316 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (527 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (312 aa)
PARP12Poly(ADP-ribose) polymerase family member 12. (699 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa)
MROH6Maestro heat like repeat family member 6. (693 aa)
LARGE1LARGE xylosyl- and glucuronyltransferase 1. (756 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
PARP3Poly [ADP-ribose] polymerase. (525 aa)
PARP4Poly [ADP-ribose] polymerase. (1739 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (855 aa)
QTRT2Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (414 aa)
PARP8Poly [ADP-ribose] polymerase. (893 aa)
RXYLT1Ribitol xylosyltransferase 1. (443 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (330 aa)
PARP1Poly [ADP-ribose] polymerase. (1020 aa)
PARP14Poly [ADP-ribose] polymerase. (1795 aa)
XYLT2Xylosyltransferase 2. (864 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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