(70 nodes) Nerve development network (Capra hircus)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (258 aa)
	NAV2	Neuron navigator 2. (2452 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	POU4F1	POU domain protein. (421 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (241 aa)
	TIFAB	TIFA inhibitor. (197 aa)
	ATP8B1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa)
	SIX4	SIX homeobox 4. (784 aa)
	PLXNA1	Plexin_cytopl domain-containing protein. (255 aa)
	EDN1	Endothelin 1. (202 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (2993 aa)
	RPL24	Ribosomal protein L24. (158 aa)
	HOXD3	Homeobox D3. (433 aa)
	KCNA2	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
	RNF165	Ring finger protein 165. (347 aa)
	NTF4	Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
	FBXO45	F-box protein 45. (281 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
	TMEM126A	Uncharacterized protein. (197 aa)
	HOXB2	Homeobox B2. (354 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	LOC102177760	Plexin A1. (1661 aa)
	SIX1	SIX homeobox 1. (284 aa)
	GABRB2	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	ECE1	Endothelin converting enzyme 1. (767 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	NTRK1	Tyrosine-protein kinase receptor. (821 aa)
	EPHB2	EPH receptor B2. (1016 aa)
	ENSCHIP00000026159	Uncharacterized protein. (163 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	PLXNA3	Plexin A3. (1822 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
	LOC108634739	TGF_BETA_2 domain-containing protein. (197 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (764 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
	ATOH7	Atonal bHLH transcription factor 7. (145 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	EPHB1	EPH receptor B1. (984 aa)
	NGFR	Nerve growth factor receptor. (427 aa)
	EGR2	Early growth response 2. (472 aa)
	POU4F3	POU domain protein. (338 aa)
	ENSCHIP00000019526	Uncharacterized protein. (102 aa)
	TFAP2A	Transcription factor AP-2 alpha. (485 aa)
	ADARB1	Adenosine deaminase RNA specific B1. (701 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	PHOX2A	Paired like homeobox 2A. (284 aa)
	HOXB1	Homeobox B1. (302 aa)
	PHOX2B	Paired like homeobox 2B. (315 aa)
	ILK	Integrin linked kinase. (452 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	CNGB1	Cyclic nucleotide-binding domain-containing protein. (1344 aa)
	AFG3L2	AFG3 like matrix AAA peptidase subunit 2. (805 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (397 aa)
	DRGX	Dorsal root ganglia homeobox. (263 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (926 aa)
	COL25A1	Collagen type XXV alpha 1 chain. (391 aa)
	DAG1	Dystroglycan 1. (895 aa)
	GLI3	GLI family zinc finger 3. (1614 aa)
	SLC24A4	Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (603 aa)
	SULF2	Sulfatase 2. (864 aa)
	HOXA3	Homeobox A3. (437 aa)
	ERBB3	Erb-b2 receptor tyrosine kinase 3. (1344 aa)
	HOXB3	Homeobox B3. (426 aa)
	NPTX1	Neuronal pentraxin 1. (432 aa)
	NEUROG1	Neurogenin 1. (246 aa)
	MAFB	MAF bZIP transcription factor B. (329 aa)
	ENSCHIP00000010266	Plexin_cytopl domain-containing protein. (255 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	TMEM126A	ENSCHIP00000016510	ENSCHIP00000031928	AFG3 like matrix AAA peptidase subunit 2.	Uncharacterized protein.	0.535
ATOH7	ISL1	ENSCHIP00000021587	ENSCHIP00000025978	Atonal bHLH transcription factor 7.	ISL LIM homeobox 1.	0.817
ATOH7	POU4F1	ENSCHIP00000021587	ENSCHIP00000001764	Atonal bHLH transcription factor 7.	POU domain protein.	0.464
ATOH7	TFAP2A	ENSCHIP00000021587	ENSCHIP00000019210	Atonal bHLH transcription factor 7.	Transcription factor AP-2 alpha.	0.682
BDNF	CTNNB1	ENSCHIP00000003028	ENSCHIP00000031016	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Catenin beta 1.	0.551
BDNF	EDN1	ENSCHIP00000003028	ENSCHIP00000008821	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Endothelin 1.	0.424
BDNF	EGR2	ENSCHIP00000003028	ENSCHIP00000019933	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Early growth response 2.	0.441
BDNF	ERBB3	ENSCHIP00000003028	ENSCHIP00000012135	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Erb-b2 receptor tyrosine kinase 3.	0.727
BDNF	GABRA5	ENSCHIP00000003028	ENSCHIP00000028092	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.440
BDNF	ISL1	ENSCHIP00000003028	ENSCHIP00000025978	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	ISL LIM homeobox 1.	0.513
BDNF	LOC108634739	ENSCHIP00000003028	ENSCHIP00000025024	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	TGF_BETA_2 domain-containing protein.	0.732
BDNF	NEUROG1	ENSCHIP00000003028	ENSCHIP00000011136	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Neurogenin 1.	0.470
BDNF	NGF	ENSCHIP00000003028	ENSCHIP00000003583	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Nerve growth factor; Belongs to the NGF-beta family.	0.822
BDNF	NGFR	ENSCHIP00000003028	ENSCHIP00000020406	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Nerve growth factor receptor.	0.975
BDNF	NTF3	ENSCHIP00000003028	ENSCHIP00000009504	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.	0.925
BDNF	NTF4	ENSCHIP00000003028	ENSCHIP00000005302	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Neurotrophin 4; Belongs to the NGF-beta family.	0.935
BDNF	NTRK1	ENSCHIP00000003028	ENSCHIP00000027302	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Tyrosine-protein kinase receptor.	0.942
BDNF	SEMA3F	ENSCHIP00000003028	ENSCHIP00000025018	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Semaphorin 3F; Belongs to the semaphorin family.	0.433
BDNF	SLC1A3	ENSCHIP00000003028	ENSCHIP00000017001	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Amino acid transporter.	0.451
CHD7	CTNNB1	ENSCHIP00000008650	ENSCHIP00000031016	Chromodomain helicase DNA binding protein 7.	Catenin beta 1.	0.576