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| | PIH1D2 | PIH1 domain containing 2. (315 aa) |
| | EIF3L | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (564 aa) |
| | LOC102171492 | Ribosomal_L18_c domain-containing protein. (285 aa) |
| | LOC102176107 | Uncharacterized protein. (361 aa) |
| | CPSF7 | Cleavage and polyadenylation specific factor 7. (471 aa) |
| | ENSCHIP00000013170 | Uncharacterized protein. (147 aa) |
| | MRTO4 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa) |
| | ENSCHIP00000013274 | Sm domain-containing protein. (87 aa) |
| | ENSCHIP00000013280 | Ribosomal_L23eN domain-containing protein. (144 aa) |
| | BRIX1 | Biogenesis of ribosomes BRX1. (344 aa) |
| | FASTKD2 | FAST kinase domains 2. (688 aa) |
| | ZNHIT3 | HIT-type domain-containing protein. (173 aa) |
| | RPL6 | 60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (287 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1304 aa) |
| | RPLP0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa) |
| | RPL5 | Ribosomal_L18_c domain-containing protein. (296 aa) |
| | CELF2 | CUGBP Elav-like family member 2. (521 aa) |
| | PRPF3 | Pre-mRNA processing factor 3. (683 aa) |
| | LOC102176643 | Tudor domain-containing protein. (295 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (119 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (129 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1922 aa) |
| | SRSF6 | Uncharacterized protein. (345 aa) |
| | GCFC2 | GC-rich sequence DNA-binding factor 2. (782 aa) |
| | ENSCHIP00000015364 | Ribosomal_L7Ae domain-containing protein. (112 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (94 aa) |
| | ENSCHIP00000015549 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (71 aa) |
| | MCTS1 | Malignant T-cell-amplified sequence. (182 aa) |
| | SNRPD2-2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (96 aa) |
| | ENSCHIP00000016090 | RRM domain-containing protein. (582 aa) |
| | LOC102173595 | Uncharacterized protein. (314 aa) |
| | SCAF11 | SR-related CTD associated factor 11. (1456 aa) |
| | EIF3A | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1368 aa) |
| | ENSCHIP00000016343 | RL10P_insert domain-containing protein. (264 aa) |
| | PSIP1 | PWWP domain-containing protein. (530 aa) |
| | ENSCHIP00000016839 | Uncharacterized protein. (240 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | YJU2 | Uncharacterized protein. (320 aa) |
| | SNRPF | Sm domain-containing protein. (68 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1175 aa) |
| | NOL3 | Nucleolar protein 3. (230 aa) |
| | LUC7L | LUC7 like. (369 aa) |
| | ENSCHIP00000017505 | Uncharacterized protein. (228 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa) |
| | DHX30 | DExH-box helicase 30. (1248 aa) |
| | RPS28 | Uncharacterized protein. (69 aa) |
| | ENSCHIP00000018433 | Ribosomal_L23eN domain-containing protein. (145 aa) |
| | ENSCHIP00000018473 | PCI domain-containing protein. (322 aa) |
| | CCDC105 | Coiled-coil domain containing 105. (500 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (948 aa) |
| | SF3A2 | Splicing factor 3a subunit 2. (477 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | NAF1 | Nuclear assembly factor 1 ribonucleoprotein. (387 aa) |
| | RBM5 | RNA binding motif protein 5. (815 aa) |
| | ENSCHIP00000019526 | Uncharacterized protein. (102 aa) |
| | SF3A1 | Splicing factor 3a subunit 1. (808 aa) |
| | NOP2 | SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (823 aa) |
| | DHX9 | DExH-box helicase 9. (1271 aa) |
| | LOC108634721 | Tr-type G domain-containing protein. (473 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | LOC102176283 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | RPS5 | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa) |
| | ENSCHIP00000021672 | Uncharacterized protein. (209 aa) |
| | ZNHIT6 | Zinc finger HIT-type containing 6. (460 aa) |
| | ENSCHIP00000022029 | HIT-type domain-containing protein. (153 aa) |
| | LOC102189373 | 40S ribosomal protein S27. (91 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (795 aa) |
| | EIF3F | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa) |
| | RPL11 | Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (178 aa) |
| | EIF4H | Eukaryotic translation initiation factor 4H. (214 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (501 aa) |
| | SNRNP200 | Small nuclear ribonucleoprotein U5 subunit 200. (2146 aa) |
| | ENSCHIP00000022906 | Ribosomal_L6e_N domain-containing protein. (253 aa) |
| | SETX | Senataxin. (2659 aa) |
| | MDN1 | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5586 aa) |
| | USP39 | Ubiquitin specific peptidase 39. (565 aa) |
| | PRPF31 | Pre-mRNA processing factor 31. (499 aa) |
| | AAR2 | AAR2 splicing factor. (384 aa) |
| | EIF5 | W2 domain-containing protein. (430 aa) |
| | LOC102190239 | PWWP domain-containing protein. (512 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa) |
| | ENSCHIP00000024316 | Malignant T-cell-amplified sequence. (182 aa) |
| | EIF3I | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa) |
| | LOC102169534 | 40S_SA_C domain-containing protein. (256 aa) |
| | RPL23A | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (178 aa) |
| | ERAL1 | Era like 12S mitochondrial rRNA chaperone 1. (437 aa) |
| | MRPS11 | Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (197 aa) |
| | ENSCHIP00000025104 | Uncharacterized protein. (62 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (736 aa) |
| | STRAP | Serine/threonine kinase receptor associated protein. (350 aa) |
| | EIF3J-2 | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (262 aa) |
| | ENSCHIP00000025506 | Uncharacterized protein. (59 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | ENSCHIP00000025772 | Uncharacterized protein. (71 aa) |
| | CLNS1A | Chloride nucleotide-sensitive channel 1A. (237 aa) |
| | ENSCHIP00000025864 | Uncharacterized protein. (90 aa) |
| | RPF2 | Ribosome production factor 2 homolog. (296 aa) |
| | ENSCHIP00000026066 | Ribosomal_L6e_N domain-containing protein. (229 aa) |
| | ENSCHIP00000026270 | Sm domain-containing protein. (62 aa) |
| | EIF3F-2 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (334 aa) |
| | KHDC4 | KH domain containing 4, pre-mRNA splicing factor. (614 aa) |
| | LOC102174301 | RL10P_insert domain-containing protein. (281 aa) |
| | ENSCHIP00000026982 | Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (173 aa) |
| | EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) |
| | RPS15 | Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (144 aa) |
| | ENSCHIP00000027351 | Uncharacterized protein. (150 aa) |
| | LOC102189480 | Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (163 aa) |
| | SRPK2 | SRSF protein kinase 2. (697 aa) |
| | CLP1 | Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa) |
| | ENSCHIP00000027702 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (68 aa) |
| | C12orf45 | Chromosome 12 open reading frame 45. (192 aa) |
| | EIF3J | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (242 aa) |
| | ENSCHIP00000028439 | Uncharacterized protein. (65 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (471 aa) |
| | CELF1 | CUGBP Elav-like family member 1. (513 aa) |
| | PTBP2 | Polypyrimidine tract binding protein 2. (537 aa) |
| | RPS19 | Uncharacterized protein. (119 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (231 aa) |
| | DENR | Density-regulated protein; Belongs to the DENR family. (198 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | ENSCHIP00000031419 | Uncharacterized protein. (69 aa) |
| | CELF3 | CUGBP Elav-like family member 3. (462 aa) |
| | TARBP2 | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (370 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1508 aa) |
| | GEMIN4 | Gem nuclear organelle associated protein 4. (1059 aa) |
| | EIF2S2 | eIF2B_5 domain-containing protein. (340 aa) |
| | PWP2 | WD_REPEATS_REGION domain-containing protein. (907 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (875 aa) |
| | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa) |
| | RRP7A | Ribosomal RNA processing 7 homolog A. (280 aa) |
| | ENSCHIP00000033224 | Uncharacterized protein. (125 aa) |
| | RPL38 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (69 aa) |
| | ENSCHIP00000033286 | Uncharacterized protein. (101 aa) |
| | MRPS7 | Mitochondrial ribosomal protein S7. (242 aa) |
| | ENSCHIP00000033775 | Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (127 aa) |
| | LOC102175840 | Uncharacterized protein. (365 aa) |
| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa) |
| | CXHXorf66 | Uncharacterized protein. (379 aa) |
| | MAP7D3 | Uncharacterized protein. (959 aa) |
| | PRPF18 | SFM domain-containing protein. (351 aa) |
| | LOC102187846 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | LOC102182120 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | PUF60 | Poly(U) binding splicing factor 60. (601 aa) |
| | ENSCHIP00000001288 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | ENSCHIP00000001299 | HA2 domain-containing protein. (363 aa) |
| | SRPK3 | SRSF protein kinase 3. (565 aa) |
| | LOC102172658 | 40S ribosomal protein S27. (83 aa) |
| | LOC102185325 | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | LOC102173098 | Ribosomal_L23eN domain-containing protein. (156 aa) |
| | LOC102189548 | Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (145 aa) |
| | RPL10L | Ribosomal protein L10 like. (214 aa) |
| | EIF3G | Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa) |
| | LOC102191473 | 40S ribosomal protein S27. (84 aa) |
| | EIF2S3 | Tr-type G domain-containing protein. (472 aa) |
| | CELF5 | CUGBP Elav-like family member 5. (479 aa) |
| | ENSCHIP00000001936 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | ENSCHIP00000002037 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | DDX39B | DExD-box helicase 39B. (428 aa) |
| | SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa) |
| | LOC108638228 | 40S ribosomal protein S27. (84 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | YTHDC1 | YTH domain containing 1. (698 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa) |
| | ENSCHIP00000002449 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (60 aa) |
| | LOC102186858 | Brix domain-containing protein. (469 aa) |
| | NUFIP1 | Nuclear FMR1 interacting protein 1. (493 aa) |
| | CELF4 | CUGBP Elav-like family member 4. (475 aa) |
| | LOC102175621 | Uncharacterized protein. (69 aa) |
| | LOC102190997 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | ENSCHIP00000003544 | Uncharacterized protein. (128 aa) |
| | LOC102173699 | 60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (287 aa) |
| | LOC102174442 | Uncharacterized protein. (284 aa) |
| | LOC102187701 | Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (133 aa) |
| | SFSWAP | Splicing factor SWAP. (994 aa) |
| | ENSCHIP00000004875 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) |
| | ENSCHIP00000004999 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (139 aa) |
| | ENSCHIP00000005003 | Uncharacterized protein. (345 aa) |
| | CELF6 | Uncharacterized protein. (459 aa) |
| | ENSCHIP00000005161 | 40S ribosomal protein S27. (83 aa) |
| | EIF2D | Eukaryotic translation initiation factor 2D. (699 aa) |
| | NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (479 aa) |
| | GEMIN8 | Gem nuclear organelle associated protein 8. (234 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (695 aa) |
| | ENSCHIP00000005535 | Uncharacterized protein. (62 aa) |
| | LOC102190045 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | DDX28 | DEAD-box helicase 28. (545 aa) |
| | LOC102172789 | Uncharacterized protein. (376 aa) |
| | ENSCHIP00000005868 | Sm domain-containing protein. (52 aa) |
| | GEMIN2 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (269 aa) |
| | ZNHIT2 | Zinc finger HIT-type containing 2. (399 aa) |
| | LOC102175427 | Uncharacterized protein. (246 aa) |
| | GEMIN7 | Gem nuclear organelle associated protein 7. (128 aa) |
| | EIF3B | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (788 aa) |
| | PRPF39 | Pre-mRNA processing factor 39. (667 aa) |
| | LOC102183623 | Uncharacterized protein. (261 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa) |
| | LOC102171808 | 40S ribosomal protein S27. (84 aa) |
| | MRPL20 | Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family. (149 aa) |
| | ENSCHIP00000006986 | RL10P_insert domain-containing protein. (210 aa) |
| | ENSCHIP00000007008 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (71 aa) |
| | CPSF6 | Cleavage and polyadenylation specific factor 6. (588 aa) |
| | SRSF1 | Uncharacterized protein. (248 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa) |
| | DDX20 | DEAD-box helicase 20. (825 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | ENSCHIP00000008108 | CS domain-containing protein. (116 aa) |
| | LOC102179869 | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | XAB2 | XPA binding protein 2. (892 aa) |
| | LOC102173750 | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | RPL24 | Ribosomal protein L24. (158 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa) |
| | LOC108633166 | eIF2B_5 domain-containing protein. (333 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | LOC102189741 | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | AGO1 | Uncharacterized protein; Belongs to the argonaute family. (916 aa) |
| | RPSA | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (294 aa) |
| | EIF3M | Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (374 aa) |
| | LOC102172949 | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa) |
| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa) |
| | ENSCHIP00000009343 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (69 aa) |
| | SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor. (638 aa) |
| | ENSCHIP00000009539 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (60 aa) |
| | EIF4B | RRM domain-containing protein. (615 aa) |
| | RPS14 | Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (151 aa) |
| | SNRPG | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | NLE1 | Notchless homolog 1. (487 aa) |
| | ENSCHIP00000009864 | Uncharacterized protein. (130 aa) |
| | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor. (491 aa) |
| | RPS27L | 40S ribosomal protein S27. (82 aa) |
| | ABT1 | Activator of basal transcription 1. (275 aa) |
| | ENSCHIP00000010524 | Ribosomal_L6e_N domain-containing protein. (228 aa) |
| | LOC102174705 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | GEMIN6 | Gem nuclear organelle associated protein 6. (166 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (693 aa) |
| | MRM2 | FtsJ domain-containing protein. (254 aa) |
| | LOC102172503 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa) |
| | BOP1 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (721 aa) |
| | DHX29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1362 aa) |
| | ENSCHIP00000011638 | DUF1785 domain-containing protein. (242 aa) |
| | ENSCHIP00000011658 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (79 aa) |
| | SLU7 | SLU7 homolog, splicing factor. (586 aa) |
| | SRPK1 | SRSF protein kinase 1. (645 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4117 aa) |
