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IGF1 IGF1 ENSCHIP00000020400 ENSCHIP00000020400 CHST10 CHST10 HS3ST5 HS3ST5 CHST8 CHST8 CHST7 CHST7 ENSCHIP00000022131 ENSCHIP00000022131 CHST3 CHST3 ACAN ACAN B3GAT1 B3GAT1 NDST1 NDST1 CANT1 CANT1 B4GALNT3 B4GALNT3 B3GAT3 B3GAT3 HS6ST1 HS6ST1 CHST9 CHST9 NDST2 NDST2 CHST13 CHST13 CSGALNACT1 CSGALNACT1 UGDH UGDH NDST4 NDST4 LOC108636856 LOC108636856 PXYLP1 PXYLP1 EXT2 EXT2 CHSY1 CHSY1 HS2ST1 HS2ST1 XYLT1 XYLT1 EXTL3 EXTL3 FAM20B FAM20B NDST3 NDST3 CHST11 CHST11 B4GALNT4 B4GALNT4 GLCE GLCE CHSY3 CHSY3 CHPF2 CHPF2 HS6ST3 HS6ST3 DSE DSE B3GALT6 B3GALT6 CHPF CHPF CSGALNACT2 CSGALNACT2 CYTL1 CYTL1 FOXL1 FOXL1 CHST14 CHST14 CHST12 CHST12 HS6ST2 HS6ST2 EXT1 EXT1 BMPR1B BMPR1B B4GALT7 B4GALT7 B3GAT2 B3GAT2 XYLT2 XYLT2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
ENSCHIP00000020400Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (292 aa)
CHST10Carbohydrate sulfotransferase. (355 aa)
HS3ST5Sulfotransferase; Belongs to the sulfotransferase 1 family. (345 aa)
CHST8Carbohydrate sulfotransferase. (424 aa)
CHST7Sulfotransferase; Belongs to the sulfotransferase 1 family. (486 aa)
ENSCHIP00000022131Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (236 aa)
CHST3Sulfotransferase; Belongs to the sulfotransferase 1 family. (479 aa)
ACANAggrecan. (2402 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (383 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
CANT1Calcium activated nucleotidase 1. (401 aa)
B4GALNT3Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (1003 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (416 aa)
CHST9Carbohydrate sulfotransferase. (442 aa)
NDST2Uncharacterized protein. (883 aa)
CHST13Carbohydrate sulfotransferase. (338 aa)
CSGALNACT1Hexosyltransferase. (524 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
NDST4N-deacetylase and N-sulfotransferase 4. (872 aa)
LOC108636856Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (301 aa)
PXYLP12-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. (480 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (737 aa)
CHSY1Hexosyltransferase. (802 aa)
HS2ST1Uncharacterized protein. (356 aa)
XYLT1Xylosyltransferase 1. (991 aa)
EXTL3Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (919 aa)
FAM20BFAM20B glycosaminoglycan xylosylkinase. (409 aa)
NDST3N-deacetylase and N-sulfotransferase 3. (887 aa)
CHST11Carbohydrate sulfotransferase. (362 aa)
B4GALNT4Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (909 aa)
GLCEGlucuronic acid epimerase. (617 aa)
CHSY3Uncharacterized protein. (313 aa)
CHPF2Hexosyltransferase. (769 aa)
HS6ST3Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (244 aa)
DSEDermatan sulfate epimerase. (989 aa)
B3GALT6Hexosyltransferase. (329 aa)
CHPFHexosyltransferase. (775 aa)
CSGALNACT2Hexosyltransferase. (540 aa)
CYTL1Cytokine like 1. (136 aa)
FOXL1Forkhead box L1. (346 aa)
CHST14Carbohydrate sulfotransferase. (376 aa)
CHST12Carbohydrate sulfotransferase. (419 aa)
HS6ST2Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (320 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (327 aa)
B3GAT2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (326 aa)
XYLT2Xylosyltransferase 2. (864 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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