55 items (Capra hircus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	GCAT	Glycine C-acetyltransferase. (433 aa)
	ETNPPL	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
	GOT1L1	Glutamic-oxaloacetic transaminase 1 like 1. (404 aa)
	OAT	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (568 aa)
	DDC	Dopa decarboxylase. (519 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	ALAS2	5-aminolevulinate synthase. (587 aa)
	ISM1	Isthmin 1. (464 aa)
	PYGM	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (857 aa)
	CBS	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (586 aa)
	ACCSL	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like. (611 aa)
	PDXDC1	Pyridoxal dependent decarboxylase domain containing 1. (794 aa)
	ENSCHIP00000005391	Aminotran_1_2 domain-containing protein. (403 aa)
	SPTLC3	Serine palmitoyltransferase long chain base subunit 3. (549 aa)
	PNPO	Pyridoxamine 5'-phosphate oxidase. (261 aa)
	ALAS1	5-aminolevulinate synthase. (647 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (889 aa)
	MTARC1	MOSC domain-containing protein. (337 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	ACCS	1-aminocyclopropane-1-carboxylate synthase homolog (inactive). (492 aa)
	PYGB	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (846 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (467 aa)
	AADAT	Aminotran_1_2 domain-containing protein. (425 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	PLPBP	Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (275 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	AGXT	Serine--pyruvate aminotransferase. (414 aa)
	CSAD	Cysteine sulfinic acid decarboxylase. (493 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
	LOC108636344	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
	SPTLC1	Serine palmitoyltransferase long chain base subunit 1. (480 aa)
	KYAT1	Aminotran_1_2 domain-containing protein. (425 aa)
	GADL1	Glutamate decarboxylase like 1. (627 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
	SPTLC2	Serine palmitoyltransferase long chain base subunit 2. (562 aa)
	SDS	Serine dehydratase. (326 aa)
	MARC2	Mitochondrial amidoxime reducing component 2. (336 aa)
	LOC102176752	Uncharacterized protein. (539 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	THNSL2	Threonine synthase like 2. (484 aa)
	KYAT3	Kynurenine aminotransferase 3. (476 aa)
	CTH	Cystathionine gamma-lyase. (415 aa)
	ALB	Serum albumin. (608 aa)
	TAT	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (447 aa)
	NFS1	Aminotran_5 domain-containing protein. (457 aa)
	GAD1	Glutamate decarboxylase 1. (594 aa)
	SRR	Serine racemase. (334 aa)
	HDC	Histidine decarboxylase. (658 aa)
	GPT2	Glutamic--pyruvic transaminase 2. (523 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	KYAT1	ENSCHIP00000030168	ENSCHIP00000015233	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.931
AADAT	KYAT3	ENSCHIP00000030168	ENSCHIP00000021831	Aminotran_1_2 domain-containing protein.	Kynurenine aminotransferase 3.	0.938
AADAT	KYNU	ENSCHIP00000030168	ENSCHIP00000031339	Aminotran_1_2 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.	0.947
AADAT	PLPBP	ENSCHIP00000030168	ENSCHIP00000027948	Aminotran_1_2 domain-containing protein.	Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.	0.574
AADAT	THNSL2	ENSCHIP00000030168	ENSCHIP00000022285	Aminotran_1_2 domain-containing protein.	Threonine synthase like 2.	0.680
ABAT	AGXT	ENSCHIP00000025460	ENSCHIP00000025932	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine--pyruvate aminotransferase.	0.531
ABAT	AGXT2	ENSCHIP00000025460	ENSCHIP00000025513	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.935
ABAT	CSAD	ENSCHIP00000025460	ENSCHIP00000032241	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Cysteine sulfinic acid decarboxylase.	0.451
ABAT	DDC	ENSCHIP00000025460	ENSCHIP00000011590	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dopa decarboxylase.	0.452
ABAT	GAD1	ENSCHIP00000025460	ENSCHIP00000018351	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 1.	0.965
ABAT	GAD2	ENSCHIP00000025460	ENSCHIP00000023476	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 2.	0.963
ABAT	GADL1	ENSCHIP00000025460	ENSCHIP00000014738	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase like 1.	0.942
ABAT	GOT1	ENSCHIP00000025460	ENSCHIP00000029101	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase.	0.523
ABAT	GOT1L1	ENSCHIP00000025460	ENSCHIP00000013967	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamic-oxaloacetic transaminase 1 like 1.	0.421
ABAT	HDC	ENSCHIP00000025460	ENSCHIP00000017431	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Histidine decarboxylase.	0.446
ABAT	LOC102176752	ENSCHIP00000025460	ENSCHIP00000023551	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.986
ABAT	SGPL1	ENSCHIP00000025460	ENSCHIP00000012320	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Sphingosine-1-phosphate lyase 1.	0.640
ACCS	CTH	ENSCHIP00000032194	ENSCHIP00000021417	1-aminocyclopropane-1-carboxylate synthase homolog (inactive).	Cystathionine gamma-lyase.	0.456
ACCS	KYNU	ENSCHIP00000032194	ENSCHIP00000031339	1-aminocyclopropane-1-carboxylate synthase homolog (inactive).	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.	0.560
ACCS	THNSL2	ENSCHIP00000032194	ENSCHIP00000022285	1-aminocyclopropane-1-carboxylate synthase homolog (inactive).	Threonine synthase like 2.	0.597