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| | TCF7 | Transcription factor 7. (418 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (535 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | LOC108635164 | AIG1-type G domain-containing protein. (314 aa) |
| | PSMB11 | Proteasome subunit beta 11. (336 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1123 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (378 aa) |
| | CD3D | CD3d molecule. (167 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | CTSV | Uncharacterized protein; Belongs to the peptidase C1 family. (334 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | ENSCHIP00000005136 | JmjC domain-containing protein. (236 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | ENSCHIP00000005590 | AIG1-type G domain-containing protein. (278 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (617 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (538 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | FUT7 | Fucosyltransferase 7. (342 aa) |
| | CD4 | CD4 molecule. (455 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (844 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | CLEC4D | C-type lectin domain family 4 member D. (212 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2993 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SRF | Serum response factor. (509 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa) |
| | ZAP70 | Tyrosine-protein kinase. (622 aa) |
| | IL6R | Interleukin 6 receptor. (441 aa) |
| | CD3E | CD3e molecule. (194 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (645 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (356 aa) |
| | SOX13 | SRY-box transcription factor 13. (592 aa) |
| | MAFB | MAF bZIP transcription factor B. (329 aa) |
| | IL7 | Interleukin 7. (181 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | SOX4 | SRY-box transcription factor 4. (504 aa) |
| | ENSCHIP00000011371 | Uncharacterized protein. (193 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (212 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (417 aa) |
| | LCK | Tyrosine-protein kinase. (509 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | CD74 | CD74 molecule. (261 aa) |
| | HLX | H2.0 like homeobox. (488 aa) |
| | FOXP3 | Forkhead box P3. (463 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (795 aa) |
| | CCR9 | C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | GLI3 | GLI family zinc finger 3. (1614 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (76 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (492 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa) |
| | RAB44 | RAB44, member RAS oncogene family. (976 aa) |
| | LY9 | Ig-like domain-containing protein. (511 aa) |
| | RUNX2 | RUNX family transcription factor 2. (585 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | BCL2 | BH4_2 domain-containing protein. (229 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa) |
| | RIPK3 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (243 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | IRF4 | Interferon regulatory factor 4. (450 aa) |
| | RABL3 | RAB, member of RAS oncogene family like 3. (236 aa) |
| | LOC102178162 | AIG1-type G domain-containing protein. (302 aa) |
| | AIRE | Autoimmune regulator. (548 aa) |
| | CD83 | CD83 molecule. (199 aa) |
| | NKX2-3 | NK2 homeobox 3. (367 aa) |
| | LOC102188370 | Uncharacterized protein. (455 aa) |
| | LOC106503900 | AIG1-type G domain-containing protein. (294 aa) |
| | CRACR2A | Calcium release activated channel regulator 2A. (723 aa) |
| | TSC1 | Uncharacterized protein. (1158 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (774 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1189 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (572 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (905 aa) |
| | THEMIS | Thymocyte selection associated. (641 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | TNFSF8 | TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa) |
| | PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (687 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | FOXN1 | Forkhead box N1. (645 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa) |
| | STAT5B | Signal transducer and activator of transcription. (808 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (364 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa) |
| | TBX21 | T-box transcription factor 21. (533 aa) |
| | JMJD6 | JmjC domain-containing protein. (414 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1067 aa) |
| | DOCK2 | DHR-1 domain-containing protein; Belongs to the DOCK family. (846 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (762 aa) |
| | GPR18 | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase. (380 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (157 aa) |
| | LEPR | Leptin receptor. (1166 aa) |
| | ENSCHIP00000027739 | Uncharacterized protein. (501 aa) |
| | ZNF683 | Uncharacterized protein. (489 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (513 aa) |
| | GIMAP1 | AIG1-type G domain-containing protein. (302 aa) |
| | SP3 | Sp3 transcription factor. (778 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (161 aa) |
| | CD28 | CD28 molecule. (228 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (527 aa) |
| | EOMES | Eomesodermin. (701 aa) |
| | SLAMF6 | Ig-like domain-containing protein. (351 aa) |
| | ZFP36L2 | ZFP36 ring finger protein like 2. (490 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | GATA3 | GATA binding protein 3. (467 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (291 aa) |
| | PAX1 | Paired box 1. (443 aa) |
| | LEF1 | HMG box domain-containing protein. (430 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | STAT6 | Signal transducer and activator of transcription. (841 aa) |
| | MR1 | Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (336 aa) |
| | PRR7 | Proline rich 7, synaptic. (270 aa) |
| | RORA | Uncharacterized protein. (527 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (539 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1250 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ARMC5 | Armadillo repeat containing 5. (939 aa) |
| | CD8A | CD8a molecule. (233 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | ADA | Adenosine deaminase. (400 aa) |
